Fetal stem-cell transplantation

Best Practice and Research in Clinical Obstetrics and Gynaecology

Volumn 22, Issue 1, 2008, Pages 189-201

  Tiblad, Eleonor ^a   Westgren, Magnus ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

fetal stem cell transplantation; hematopoietic stem cell transplantation; in utero transplantation

Indexed keywords

ALLOANTIGEN;

ALLOGENEIC STEM CELL TRANSPLANTATION; CELL MATURATION; CELL MIGRATION; FETUS; HEMATOLOGIC DISEASE; HUMAN; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IN UTERO STEM CELL TRANSPLANTATION; METABOLIC DISORDER; NONHUMAN; PRENATAL PERIOD; PRIORITY JOURNAL; REVIEW; TRANSPLANTATION TOLERANCE;

ANIMALS; DISEASE MODELS, ANIMAL; FETAL DISEASES; FETAL STEM CELLS; FETUS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNE SYSTEM; MICE; SHEEP;

EID: 39049115047     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2007.07.007     Document Type: Review

References (78)

1. Flake A.W., and Zanjani E.D. In utero hematopoietic stem cell transplantation: ontogenic opportunities and biologic barriers. Blood 94 (1999) 2179-2191
2. Harrison M.R. Fetal surgery. West J Med 159 (1993) 341-349
3. Harrison M.R., Golbus M.S., and Filly R.A. Management of the fetus with a correctable congenital defect. JAMA 246 (1981) 774-777
4. Davies J. Clinicopathological conference. A case of haemolytic disease with congenital rubella demonstrated at the royal postgraduate medical school. Br Med J 2 (1967) 819-822
5. Touraine J.L., Raudrant D., Royo C., et al. In-utero transplantation of stem cells in bare lymphocyte syndrome. Lancet 1 (1989) 1382
6. Flake A.W., Roncarolo M.G., Puck J.M., et al. Treatment of x-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. N Engl J Med 335 (1996) 1806-1810
7. Lanfranchi A., Neva A., Tettoni K., et al. In utero transplantation (iut) of parental cd34+ cells in patient affected by primary immunodeficiencies. Bone Marrow Transplant 21 (1998) S127
8. Westgren M., Ringden O., Bartmann P., et al. Prenatal t-cell reconstitution after in utero transplantation with fetal liver cells in a patient with x-linked severe combined immunodeficiency. Am J Obstet Gynecol 187 (2002) 475-482
9. Burt R.K. Clinical utility in maximizing cd34+ cell count in stem cell grafts. Stem Cells 17 (1999) 373-376
10. Billingham R.E., Brent L., and Medawar P.B. 'actively acquired tolerance' of foreign cells. 1953. Transplantation 76 (2003) 1409-1412
11. Blazar B.R., Taylor P.A., and Vallera D.A. In utero transfer of adult bone marrow cells into recipients with severe combined immunodeficiency disorder yields lymphoid progeny with t- and b-cell functional capabilities. Blood 86 (1995) 4353-4366
12. Fleischman R.A., and Mintz B. Prevention of genetic anemias in mice by microinjection of normal hematopoietic stem cells into the fetal placenta. Proc Natl Acad Sci U S A 76 (1979) 5736-5740
13. Mintz B., Anthony K., and Litwin S. Monoclonal derivation of mouse myeloid and lymphoid lineages from totipotent hematopoietic stem cells experimentally engrafted in fetal hosts. Proc Natl Acad Sci U S A 81 (1984) 7835-7839
14. Carrier E., Lee T.H., Busch M.P., et al. Induction of tolerance in nondefective mice after in utero transplantation of major histocompatibility complex-mismatched fetal hematopoietic stem cells. Blood 86 (1995) 4681-4690
15. Hajdu K., Tanigawara S., McLean L.K., et al. In utero allogeneic hematopoietic stem cell transplantation to induce tolerance. Fetal Diagn Ther 11 (1996) 241-248
16. Kim H.B., Shaaban A.F., Yang E.Y., et al. Microchimerism and tolerance after in utero bone marrow transplantation in mice. J Surg Res 77 (1998) 1-5
17. Brecher G., Tjio J.H., Haley J.E., et al. Transplantation of murine bone marrow without prior host irradiation. Blood Cells 5 (1979) 237-246
18. Slavin S., Nagler A., Aker M., et al. Non-myeloablative stem cell transplantation and donor lymphocyte infusion for the treatment of cancer and life-threatening non-malignant disorders. Rev Clin Exp Hematol 5 (2001) 135-146
19. Stewart F.M., Crittenden R.B., Lowry P.A., et al. Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice. Blood 81 (1993) 2566-2571
20. Sykes M., Preffer F., McAfee S., et al. Mixed lymphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and hla-mismatched bone-marrow transplantation. Lancet 353 (1999) 1755-1759
21. Hayashi S., Peranteau W.H., Shaaban A.F., et al. Complete allogeneic hematopoietic chimerism achieved by a combined strategy of in utero hematopoietic stem cell transplantation and postnatal donor lymphocyte infusion. Blood 100 (2002) 804-812
22. Peranteau W.H., Hayashi S., Hsieh M., et al. High-level allogeneic chimerism achieved by prenatal tolerance induction and postnatal nonmyeloablative bone marrow transplantation. Blood 100 (2002) 2225-2234
23. Flake A.W., Harrison M.R., Adzick N.S., et al. Transplantation of fetal hematopoietic stem cells in utero: the creation of hematopoietic chimeras. Science 233 (1986) 776-778
24. Zanjani E.D., Ascensao J.L., Flake A.W., et al. The fetus as an optimal donor and recipient of hemopoietic stem cells. Bone Marrow Transplant 10 Suppl 1 (1992) 107-114
25. Zanjani E.D., Ascensao J.L., and Tavassoli M. Liver-derived fetal hematopoietic stem cells selectively and preferentially home to the fetal bone marrow. Blood 81 (1993) 399-404
26. Crombleholme T.M., Harrison M.R., and Zanjani E.D. In utero transplantation of hematopoietic stem cells in sheep: the role of t cells in engraftment and graft-versus-host disease. J Pediatr Surg 25 (1990) 885-892
27. Zanjani E.D., Almeida-Porada G., Ascensao J.L., et al. Transplantation of hematopoietic stem cells in utero. Stem Cells 15 Suppl 1 (1997) 79-92 discussion 93
28. Hedrick M.H., Rice H.E., MacGillivray T.E., et al. Hematopoietic chimerism achieved by in utero hematopoietic stem cell injection does not induce donor-specific tolerance for renal allografts in sheep. Transplantation 58 (1994) 110-111
29. Flake A.W., Hendrick M.H., Rice H.E., et al. Enhancement of human hematopoiesis by mast cell growth factor in human-sheep chimeras created by the in utero transplantation of human fetal hematopoietic cells. Exp Hematol 23 (1995) 252-257
30. Zanjani E.D., Flake A.W., Rice H., et al. Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep. J Clin Invest 93 (1994) 1051-1055
31. Pearce R.D., Kiehm D., Armstrong D.T., et al. Induction of hemopoietic chimerism in the caprine fetus by intraperitoneal injection of fetal liver cells. Experientia 45 (1989) 307-308
32. Westlake V.J., Jolly R.D., Jones B.R., et al. Hematopoietic cell transplantation in fetal lambs with ceroid-lipofuscinosis. Am J Med Genet 57 (1995) 365-368
33. Almeida-Porada G., Flake A.W., Glimp H.A., et al. Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero. Exp Hematol 27 (1999) 1569-1575
34. Almeida-Porada G., Porada C.D., Tran N., et al. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation. Blood 95 (2000) 3620-3627
35. Blakemore K., Hattenburg C., Stetten G., et al. In utero hematopoietic stem cell transplantation with haploidentical donor adult bone marrow in a canine model. Am J Obstet Gynecol 190 (2004) 960-973
36. Harrison M.R., Slotnick R.N., Crombleholme T.M., et al. In-utero transplantation of fetal liver haemopoietic stem cells in monkeys. Lancet 2 (1989) 1425-1427
37. Brent L., Linch D.C., Rodeck C.H., et al. On the feasibility of inducing tolerance in man: A study in the cynomolgus monkey. Immunol Lett 21 (1989) 55-61
38. Roodman G.D., Kuehl T.J., Vandeberg J.L., et al. In utero bone marrow transplantation of fetal baboons with mismatched adult baboon marrow. Blood Cells 17 (1991) 367-375
39. Cowan M.J., Tarantal A.F., Capper J., et al. Long-term engraftment following in utero t cell-depleted parental marrow transplantation into fetal rhesus monkeys. Bone Marrow Transplant 17 (1996) 1157-1165
40. Shields L.E., Gaur L.K., Gough M., et al. In utero hematopoietic stem cell transplantation in nonhuman primates: The role of t cells. Stem Cells 21 (2003) 304-314
41. Shields L.E., Gaur L., Delio P., et al. Fetal immune suppression as adjunctive therapy for in utero hematopoietic stem cell transplantation in nonhuman primates. Stem Cells 22 (2004) 759-769
42. Forestier F., Daffos F., Catherine N., et al. Developmental hematopoiesis in normal human fetal blood. Blood 77 (1991) 2360-2363
43. Clerici M., DePalma L., Roilides E., et al. Analysis of t helper and antigen-presenting cell functions in cord blood and peripheral blood leukocytes from healthy children of different ages. J Clin Invest 91 (1993) 2829-2836
44. Serushago B., Issekutz A.C., Lee S.H., et al. Deficient tumor necrosis factor secretion by cord blood mononuclear cells upon in vitro stimulation with listeria monocytogenes. J Interferon Cytokine Res 16 (1996) 381-387
45. Weston W.L., Carson B.S., Barkin R.M., et al. Monocyte-macrophage function in the newborn. Am J Dis Child 131 (1977) 1241-1242
46. Uksila J., Lassila O., Hirvonen T., et al. Development of natural killer cell function in the human fetus. J Immunol 130 (1983) 153-156
47. Thilaganathan B., Abbas A., and Nicolaides K.H. Fetal blood natural killer cells in human pregnancy. Fetal Diagn Ther 8 (1993) 149-153
48. Renda M.C., Fecarotta E., Dieli F., et al. Evidence of alloreactive t lymphocytes in fetal liver: implications for fetal hematopoietic stem cell transplantation. Bone Marrow Transplant 25 (2000) 135-141
49. Stites D.P., Carr M.C., and Fudenberg H.H. Ontogeny of cellular immunity in the human fetus: development of responses to phytohemagglutinin and to allogeneic cells. Cell Immunol 11 (1974) 257-271
50. Toivanen P., Uksila J., Leino A., et al. Development of mitogen responding t cells and natural killer cells in the human fetus. Immunol Rev 57 (1981) 89-105
51. von Hoegen P., Sarin S., and Krowka J.F. Deficiency in t cell responses of human fetal lymph node cells: a lack of accessory cells. Immunol Cell Biol 73 (1995) 353-361
52. Lindton B., Markling L., Ringden O., et al. Mixed lymphocyte culture of human fetal liver cells. Fetal Diagn Ther 15 (2000) 71-78
53. Thilaganathan B., Nicolaides K.H., Mansur C.A., et al. Fetal b lymphocyte subpopulations in normal pregnancies. Fetal Diagn Ther 8 (1993) 15-21
54. Anasetti C., Amos D., Beatty P.G., et al. Effect of hla compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma. N Engl J Med 320 (1989) 197-204
55. Beatty P.G., Clift R.A., Mickelson E.M., et al. Marrow transplantation from related donors other than hla-identical siblings. N Engl J Med 313 (1985) 765-771
56. Jankowski R.A., and Ildstad S.T. Chimerism and tolerance: From freemartin cattle and neonatal mice to humans. Hum Immunol 52 (1997) 155-161
57. Hayward A., Ambruso D., Battaglia F., et al. Microchimerism and tolerance following intrauterine transplantation and transfusion for alpha-thalassemia-1. Fetal Diagn Ther 13 (1998) 8-14
58. Westgren M., Ringden O., Eik-Nes S., et al. Lack of evidence of permanent engraftment after in utero fetal stem cell transplantation in congenital hemoglobinopathies. Transplantation 61 (1996) 1176-1179
59. Diukman R., and Golbus M.S. In utero stem cell therapy. J Reprod Med 37 (1992) 515-520
60. Monni G., Ibba R.M., Zoppi M.A., et al. In utero stem cell transplantation. Croat Med J 39 (1998) 220-223
61. Cowan M.J., and Golbus M. In utero hematopoietic stem cell transplantation for inherited diseases. Am J Pediatr Hematol Oncol 16 (1994) 35-42
62. Slavin S., Naparstek E., Ziegler M., et al. Clinical application of intrauterine bone marrow transplantation for treatment of genetic diseases-feasibility studies. Bone Marrow Transplant 9 Suppl 1 (1992) 189-190
63. Touraine J.L., Raudrant D., Golfier F., et al. Reappraisal of in utero stem cell transplantation based on long-term results. Fetal Diagn Ther 19 (2004) 305-312
64. Touraine J.L., Raudrant D., Royo C., et al. In utero transplantation of hemopoietic stem cells in humans. Transplant Proc 23 (1991) 1706-1708
65. Renda M.C., Daimiani G., Fecarotta E., et al. In utero stem cell transplantation after a mild immunosuppression:evidence of paternal ABO cDNA in B -thalassemia affected fetus. Blood Transfus 3 (2005) 55-65
66. Bambach B.J., Moser H.W., Blakemore K., et al. Engraftment following in utero bone marrow transplantation for globoid cell leukodystrophy. Bone Marrow Transplant 19 (1997) 399-402
67. Muench M.O., Rae J., Barcena A., et al. Transplantation of a fetus with paternal thy-1(+)cd34(+)cells for chronic granulomatous disease. Bone Marrow Transplant 27 (2001) 355-364
68. Porta F., Mazzolari E., Zucca S., et al. Prenatal transplant in a fetus affected by omenn syndrome. Bone Marrow Transplant 25 S (2000) S43
69. Wengler G.S., Lanfranchi A., Frusca T., et al. In-utero transplantation of parental cd34 haematopoietic progenitor cells in a patient with x-linked severe combined immunodeficiency (scidxi). Lancet 348 (1996) 1484-1487
70. Flake A.W., and Zanjani E.D. In utero hematopoietic stem cell transplantation. A status report. JAMA 278 (1997) 932-937
71. Leung W., Blakemore K., Jones R.J., et al. A human-murine chimera model for in utero human hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 5 (1999) 1-7
72. Le Blanc K., Gotherstrom C., Ringden O., et al. Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation 79 (2005) 1607-1614
73. Di Nicola M., Carlo-Stella C., Magni M., et al. Human bone marrow stromal cells suppress t-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99 (2002) 3838-3843
74. Gotherstrom C., Ringden O., Tammik C., et al. Immunologic properties of human fetal mesenchymal stem cells. Am J Obstet Gynecol 190 (2004) 239-245
75. Gotherstrom C., Ringden O., Westgren M., et al. Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells. Bone Marrow Transplant 32 (2003) 265-272
76. Orlandi F., Giambona A., Messana F., et al. Evidence of induced non-tolerance in HLA-identical twins with hemoglobinopathy after in utero fetal transplantation. Bone Marrow Transplant 18 3 (1996) 637-639
77. Linch D.S., Rodeck C.H., and Nicolaides K. Attempted bone-marrow transplantation in a 17-week fetus. Lancet 2 (1986) 1453
78. Thiliaganathan B., and Nicolaides K. Intrauterine bone marrow transplantationb at 12 weeks geatation. Lancet 342 (1993) 243