Styrene-oxide N-terminal valine haemoglobin adducts as biomarkers of occupational exposure to styrene

International Journal of Hygiene and Environmental Health

Volumn 211, Issue 1-2, 2008, Pages 59-62

  Teixeira, J P ^a   Silva, S ^a   Torres, J ^a   Gaspar, J ^b   Roach, J ^c   Farmer, P B ^c   Rueff, J ^b   Mayan, O ^a  

^a NATIONAL INSTITUTE OF HEALTH   (Portugal)

^b NOVA MEDICAL SCHOOL   (Portugal)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Haemoglobin adducts; Occupational exposure; Styrene

Indexed keywords

EID: 39049108666     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2007.02.008     Document Type: Article

References (12)

1. ACGIH (American Conference of the Governmental Industrial Hygienists), 2003. Styrene, monomer in ACGIH documentation of the threshold limit values and biological exposure indices. Science Group ACGIH, Cincinnati, OH.
2. Bond J. Review of the toxicology of styrene. Crit. Rev. Toxicol. 19 (1989) 227-249
3. Christakopoulos A., Bergmark E., Zorcec V., Norppa H., Maki-Paakkanen J., and Osterman-Golkar S. Monitoring of occupational exposure to styrene from hemoglobin adducts and metabolites in blood. Scand. J. Work Environ. Health 19 (1993) 255-263
4. Farmer P.B., Bailey E., Naylor S., Anderson D., Brooks A., Cushnir J., Lamb J.H., Sepai O., and Tang Y. Identification of endogenous electrophiles by means of mass spectrometric determination of protein and DNA adducts. Environ. Health Perspect. 99 (1993) 19-24
5. Fustinoni S., Colosio C., Colombi A., Lastrucci L., Yeowell-O′Connel K., and Rappaport S.M. Albumin and hemoglobin adducts as biomarkers of exposure to styrene in fiberglass-reinforced-plastics workers. Int. Arch. Occup. Environ. Health 71 (1998) 35-41
6. Guillemin M., Bauer D., Martin B., and Marazzi A. Human exposure to styrene. IV. Industrial hygiene investigations and biological monitoring in the polyester industry. Int. Arch. Occup. Environ. Health 51 (1982) 139-150
7. Kensler T.W., Groopman J.D., and Wogan G.N. Use of carcinogen-DNA and carcinogen-protein adduct biomarkers for cohort selection and as modifiable end points in chemoprevention trials. In: Stewart B.W., McGregor D., and Kleihues P. (Eds). Principles of Chemoprevention (1996), IARC, Lyon 237-248
8. Kivisto H., Pekari K., and Aitio A. Analysis and stability of phenylglyoxylic and mandelic acids in urine of styrene-exposed people. Int. Arch. Environ. Health 64 (1993) 399-403
9. Laffon B., Pasaro E., and Mendez J. Evaluation of genotoxic effects in a group of workers exposed to low levels of styrene. Toxicology 171 (2002) 175-186
10. Pauwels W., Farmer P.B., Osterman-Golkar S., Severi M., Cordero R., Bailey E., and Veulemans H. Ring test for the determination of N-terminal valine adducts of styrene 7,8-oxide with haemoglobin by the modified Edman degradation technique. J. Chromatogr. 702 (1997) 77-83
11. Rappaport S.M., Yeowell-O'Connell K., Bodell W., Yager J.W., and Symanski E. An investigation of cancer biomarkers among workers exposed to styrene and styrene-7,8-oxide. Cancer Res. 56 (1996) 5410-5416
12. Skipper P.L., and Tannenbaum S.R. Protein adducts in the molecular dosimetry of chemical carcinogens. Carcinogenesis 11 (1990) 507-518