메뉴 건너뛰기




Volumn 19, Issue 3, 2008, Pages 329-337

Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra

Author keywords

Alendronate; Anti remodeling; Bone markers; Pentosidine; Raloxifene; Risedronate

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN; DEOXYPYRIDINOLINE; PENTOSIDINE; PYRIDINOLINE; RALOXIFENE; RISEDRONIC ACID;

EID: 39049106609     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-007-0533-7     Document Type: Article
Times cited : (118)

References (55)
  • 2
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: A randomized controlled trial. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
    • Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T, Keller M, Chesnut CH 3rd, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 282:1344-1352
    • (1999) JAMA , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3    McKeever, C.D.4    Hangartner, T.5    Keller, M.6    Chesnut III, C.H.7    Brown, J.8    Eriksen, E.F.9    Hoseyni, M.S.10    Axelrod, D.W.11    Miller, P.D.12
  • 3
    • 12944291524 scopus 로고    scopus 로고
    • Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group
    • Reginster J, Minne HW, Sorensen OH, Hooper M, Roux C, Brandi ML, Lund B, Ethgen D, Pack S, Roumagnac I, Eastell R (2000) Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group. Osteoporos Int 11:83-91
    • (2000) Osteoporos Int , vol.11 , pp. 83-91
    • Reginster, J.1    Minne, H.W.2    Sorensen, O.H.3    Hooper, M.4    Roux, C.5    Brandi, M.L.6    Lund, B.7    Ethgen, D.8    Pack, S.9    Roumagnac, I.10    Eastell, R.11
  • 5
    • 1842610920 scopus 로고    scopus 로고
    • Alendronate produces greater effects than raloxifene on bone density and bone turnover in postmenopausal women with low bone density: Results of EFFECT (Efficacy of FOSAMAX versus EVISTA Comparison Trial) International
    • Sambrook PN, Geusens P, Ribot C, Solimano JA, Ferrer-Barriendos J, Gaines K, Verbruggen N, Melton ME (2004) Alendronate produces greater effects than raloxifene on bone density and bone turnover in postmenopausal women with low bone density: results of EFFECT (Efficacy of FOSAMAX versus EVISTA Comparison Trial) International. J Intern Med 255:503-511
    • (2004) J Intern Med , vol.255 , pp. 503-511
    • Sambrook, P.N.1    Geusens, P.2    Ribot, C.3    Solimano, J.A.4    Ferrer-Barriendos, J.5    Gaines, K.6    Verbruggen, N.7    Melton, M.E.8
  • 7
    • 0034080243 scopus 로고    scopus 로고
    • How does antiresorptive therapy decrease the risk of fracture in women with osteoporosis?
    • Delmas PD (2000) How does antiresorptive therapy decrease the risk of fracture in women with osteoporosis? Bone 27:1-3
    • (2000) Bone , vol.27 , pp. 1-3
    • Delmas, P.D.1
  • 8
    • 1642292806 scopus 로고    scopus 로고
    • Changes in bone mineral density explain little of the reduction in vertebral or nonvertebral fracture risk with anti-resorptive therapy
    • Delmas PD, Seeman E (2004) Changes in bone mineral density explain little of the reduction in vertebral or nonvertebral fracture risk with anti-resorptive therapy. Bone 34:599-604
    • (2004) Bone , vol.34 , pp. 599-604
    • Delmas, P.D.1    Seeman, E.2
  • 10
    • 0033755981 scopus 로고    scopus 로고
    • Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women
    • Boivin GY, Chavassieux PM, Santora AC, Yates J, Meunier PJ (2000) Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women. Bone 27:687-694
    • (2000) Bone , vol.27 , pp. 687-694
    • Boivin, G.Y.1    Chavassieux, P.M.2    Santora, A.C.3    Yates, J.4    Meunier, P.J.5
  • 11
    • 0032851002 scopus 로고    scopus 로고
    • Intermittent and continuous administration of the bisphosphonate ibandronate in ovariohysterectomized beagle dogs: Effects on bone morphometry and mineral properties
    • Monier-Faugere MC, Geng Z, Paschalis EP, Qi Q, Arnala I, Bauss F, Boskey AL, Malluche HH (1999) Intermittent and continuous administration of the bisphosphonate ibandronate in ovariohysterectomized beagle dogs: effects on bone morphometry and mineral properties. J Bone Miner Res 14:1768-1778
    • (1999) J Bone Miner Res , vol.14 , pp. 1768-1778
    • Monier-Faugere, M.C.1    Geng, Z.2    Paschalis, E.P.3    Qi, Q.4    Arnala, I.5    Bauss, F.6    Boskey, A.L.7    Malluche, H.H.8
  • 13
    • 0034141218 scopus 로고    scopus 로고
    • Collagen fragments in urine derived from bone resorption are highly racemized and isomerized: A biological clock of protein aging with clinical potential
    • Pt 3
    • Cloos PA, Fledelius C (2000) Collagen fragments in urine derived from bone resorption are highly racemized and isomerized: a biological clock of protein aging with clinical potential. Biochem J 345(Pt 3):473-480
    • (2000) Biochem J , vol.345 , pp. 473-480
    • Cloos, P.A.1    Fledelius, C.2
  • 14
    • 0030763499 scopus 로고    scopus 로고
    • Decreased beta-isomerization of the C-terminal telopeptide of type I collagen alpha 1 chain in Paget's disease of bone
    • Garnero P, Fledelius C, Gineyts E, Serre CM, Vignot E, Delmas PD (1997) Decreased beta-isomerization of the C-terminal telopeptide of type I collagen alpha 1 chain in Paget's disease of bone. J Bone Miner Res 12:1407-1415
    • (1997) J Bone Miner Res , vol.12 , pp. 1407-1415
    • Garnero, P.1    Fledelius, C.2    Gineyts, E.3    Serre, C.M.4    Vignot, E.5    Delmas, P.D.6
  • 15
    • 0036309121 scopus 로고    scopus 로고
    • The contribution of the organic matrix to bone's material properties
    • Burr D (2002) The contribution of the organic matrix to bone's material properties. Bone 31:8-11
    • (2002) Bone , vol.31 , pp. 8-11
    • Burr, D.1
  • 16
    • 33748175899 scopus 로고    scopus 로고
    • Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate
    • Allen MR, Iwata K, Phipps R, Burr DB (2006) Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate. Bone 39:872-879
    • (2006) Bone , vol.39 , pp. 872-879
    • Allen, M.R.1    Iwata, K.2    Phipps, R.3    Burr, D.B.4
  • 17
    • 33749537051 scopus 로고    scopus 로고
    • Raloxifene enhances vertebral mechanical properties independent of bone density
    • Allen MR, Iwata K, Sato M, Burr DB (2006) Raloxifene enhances vertebral mechanical properties independent of bone density. Bone 39:1130-1135
    • (2006) Bone , vol.39 , pp. 1130-1135
    • Allen, M.R.1    Iwata, K.2    Sato, M.3    Burr, D.B.4
  • 19
    • 0034065559 scopus 로고    scopus 로고
    • Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib
    • Mashiba T, Hirano T, Turner CH, Forwood MR, Johnston CC, Burr DB (2000) Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res 15:613-620
    • (2000) J Bone Miner Res , vol.15 , pp. 613-620
    • Mashiba, T.1    Hirano, T.2    Turner, C.H.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 20
    • 0035004850 scopus 로고    scopus 로고
    • Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles
    • Mashiba T, Turner CH, Hirano T, Forwood MR, Johnston CC, Burr DB (2001) Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles. Bone 28:524-531
    • (2001) Bone , vol.28 , pp. 524-531
    • Mashiba, T.1    Turner, C.H.2    Hirano, T.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 21
    • 39049098906 scopus 로고    scopus 로고
    • Mineralization, Microdamage, and matrix: How bisphosphonates influence material properties of bone
    • Allen MR, Burr DB (2007) Mineralization, microdamage, and matrix: how bisphosphonates influence material properties of bone. BoneKEy 4:49-60; http://www.bonekey-ibms.org/cgi/content/abstract/ibmske;44/42/49
    • (2007) BoneKEy , vol.4 , pp. 49-60
    • Allen, M.R.1    Burr, D.B.2
  • 23
    • 33749518488 scopus 로고    scopus 로고
    • Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae
    • Viguet-Carrin S, Roux JP, Arlot ME, Merabet Z, Leeming DJ, Byrjalsen I, Delmas PD, Bouxsein ML (2006) Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 39:1073-1079
    • (2006) Bone , vol.39 , pp. 1073-1079
    • Viguet-Carrin, S.1    Roux, J.P.2    Arlot, M.E.3    Merabet, Z.4    Leeming, D.J.5    Byrjalsen, I.6    Delmas, P.D.7    Bouxsein, M.L.8
  • 24
    • 0025948114 scopus 로고
    • Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors
    • Grandhee SK, Monnier VM (1991) Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors. J Biol Chem 266:11649-11653
    • (1991) J Biol Chem , vol.266 , pp. 11649-11653
    • Grandhee, S.K.1    Monnier, V.M.2
  • 25
    • 3042730990 scopus 로고    scopus 로고
    • An immunoassay for measuring fragments of newly synthesized collagen type I produced during metastatic invasion of bone
    • Cloos PA, Lyubimova N, Solberg H, Qvist P, Christiansen C, Byrjalsen I, Christgau S (2004) An immunoassay for measuring fragments of newly synthesized collagen type I produced during metastatic invasion of bone. Clin Lab 50:279-289
    • (2004) Clin Lab , vol.50 , pp. 279-289
    • Cloos, P.A.1    Lyubimova, N.2    Solberg, H.3    Qvist, P.4    Christiansen, C.5    Byrjalsen, I.6    Christgau, S.7
  • 27
    • 0019465480 scopus 로고
    • The influence of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on lysine hydroxylation and cross-link formation in rat bone, cartilage and skin collagen
    • Guenther HL, Guenther HE, Fleisch H (1981) The influence of 1-hydroxyethane-1,1-diphosphonate and dichloromethanediphosphonate on lysine hydroxylation and cross-link formation in rat bone, cartilage and skin collagen. Biochem J 196:303-310
    • (1981) Biochem J , vol.196 , pp. 303-310
    • Guenther, H.L.1    Guenther, H.E.2    Fleisch, H.3
  • 28
    • 0029987370 scopus 로고    scopus 로고
    • Molecular site specificity of pyridinoline and pyrrole cross-links in type I collagen of human bone
    • Hanson DA, Eyre DR (1996) Molecular site specificity of pyridinoline and pyrrole cross-links in type I collagen of human bone. J Biol Chem 271:26508-26516
    • (1996) J Biol Chem , vol.271 , pp. 26508-26516
    • Hanson, D.A.1    Eyre, D.R.2
  • 29
    • 0036708153 scopus 로고    scopus 로고
    • Mechanical properties of adult vertebral cancellous bone: Correlation with collagen intermolecular cross-links
    • Banse X, Sims TJ, Bailey AJ (2002) Mechanical properties of adult vertebral cancellous bone: correlation with collagen intermolecular cross-links. J Bone Miner Res 17:1621-1628
    • (2002) J Bone Miner Res , vol.17 , pp. 1621-1628
    • Banse, X.1    Sims, T.J.2    Bailey, A.J.3
  • 30
    • 0032788395 scopus 로고    scopus 로고
    • Age-related changes in the biochemical properties of human cancellous bone collagen: Relationship to bone strength
    • Bailey AJ, Sims TJ, Ebbesen EN, Mansell JP, Thomsen JS, Mosekilde L (1999) Age-related changes in the biochemical properties of human cancellous bone collagen: relationship to bone strength. Calcif Tissue Int 65:203-210
    • (1999) Calcif Tissue Int , vol.65 , pp. 203-210
    • Bailey, A.J.1    Sims, T.J.2    Ebbesen, E.N.3    Mansell, J.P.4    Thomsen, J.S.5    Mosekilde, L.6
  • 31
    • 0028801170 scopus 로고
    • Reduced concentrations of collagen cross-links are associated with reduced strength of bone
    • Oxlund H, Barckman M, Ortoft G, Andreassen TT (1995) Reduced concentrations of collagen cross-links are associated with reduced strength of bone. Bone 17:365S-371S
    • (1995) Bone , vol.17
    • Oxlund, H.1    Barckman, M.2    Ortoft, G.3    Andreassen, T.T.4
  • 32
    • 0029955513 scopus 로고    scopus 로고
    • Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis
    • Oxlund H, Mosekilde L, Ortoft G (1996) Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis. Bone 19:479-484
    • (1996) Bone , vol.19 , pp. 479-484
    • Oxlund, H.1    Mosekilde, L.2    Ortoft, G.3
  • 33
    • 0026681853 scopus 로고
    • Post-translational modifications in the collagen of human osteoporotic femoral head
    • Bailey AJ, Wotton SF, Sims TJ, Thompson PW (1992) Post-translational modifications in the collagen of human osteoporotic femoral head. Biochem Biophys Res Commun 185:801-805
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 801-805
    • Bailey, A.J.1    Wotton, S.F.2    Sims, T.J.3    Thompson, P.W.4
  • 34
    • 0025023054 scopus 로고
    • BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: Corresponding variation of sonic velocity and equatorial diffraction spacing
    • Lees S, Eyre DR, Barnard SM (1990) BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing. Connect Tissue Res 24:95-105
    • (1990) Connect Tissue Res , vol.24 , pp. 95-105
    • Lees, S.1    Eyre, D.R.2    Barnard, S.M.3
  • 35
    • 0024376778 scopus 로고
    • Toward a Maillard reaction theory of aging
    • Monnier VM (1989) Toward a Maillard reaction theory of aging. Prog Clin Biol Res 304:1-22
    • (1989) Prog Clin Biol Res , vol.304 , pp. 1-22
    • Monnier, V.M.1
  • 36
    • 0032401898 scopus 로고    scopus 로고
    • Mechanisms of maturation and ageing of collagen
    • Bailey AJ, Paul RG, Knott L (1998) Mechanisms of maturation and ageing of collagen. Mech Ageing Dev 106:1-56
    • (1998) Mech Ageing Dev , vol.106 , pp. 1-56
    • Bailey, A.J.1    Paul, R.G.2    Knott, L.3
  • 37
    • 33749526693 scopus 로고    scopus 로고
    • Age-related loss in bone toughness is explained by non-enzymatic glycation of collagen
    • Vashishth D, Wu P, Gibson G (2004) Age-related loss in bone toughness is explained by non-enzymatic glycation of collagen. Trans Orthop Res Soc 29
    • (2004) Trans Orthop Res Soc , vol.29
    • Vashishth, D.1    Wu, P.2    Gibson, G.3
  • 38
    • 33645453283 scopus 로고    scopus 로고
    • Loading on non-enzymatically glycated and damaged bone results in an instantaneous fracture
    • Wu P, Koharski C, Nonnenmann H, Vashishth D (2003) Loading on non-enzymatically glycated and damaged bone results in an instantaneous fracture. Trans Orthop Res Soc 28:404
    • (2003) Trans Orthop Res Soc , vol.28 , pp. 404
    • Wu, P.1    Koharski, C.2    Nonnenmann, H.3    Vashishth, D.4
  • 39
    • 0033300122 scopus 로고    scopus 로고
    • Increased cross-linking by non-enzymatic glycation reduces the ductility of bone and bone collagen
    • Catanese J, Bank R, Tekoppele J, Keaveny T (1999) Increased cross-linking by non-enzymatic glycation reduces the ductility of bone and bone collagen. Proc ASME 1999 Bioengineering Conference 42:267-268
    • (1999) Proc ASME 1999 Bioengineering Conference , vol.42 , pp. 267-268
    • Catanese, J.1    Bank, R.2    Tekoppele, J.3    Keaveny, T.4
  • 41
    • 33645461167 scopus 로고    scopus 로고
    • Nonenzymatic glycation affects bone fracture by modifying creep and inelastic properties of collagen
    • Boxberger J, Vashishth D (2004) Nonenzymatic glycation affects bone fracture by modifying creep and inelastic properties of collagen. Trans Orthop Res Soc 29
    • (2004) Trans Orthop Res Soc , vol.29
    • Boxberger, J.1    Vashishth, D.2
  • 42
    • 32844457410 scopus 로고    scopus 로고
    • Nonenzymatic glycation causes loss of toughening mechanisms in human cancellous bone
    • Tang S, Sharan A, Novak E, Ford T, Vashishth D (2005) Nonenzymatic glycation causes loss of toughening mechanisms in human cancellous bone. Trans Orthop Res Soc 30
    • (2005) Trans Orthop Res Soc , vol.30
    • Tang, S.1    Sharan, A.2    Novak, E.3    Ford, T.4    Vashishth, D.5
  • 43
    • 0036313364 scopus 로고    scopus 로고
    • Age-related changes in the collagen network and toughness of bone
    • Wang X, Shen X, Li X, Agrawal CM (2002) Age-related changes in the collagen network and toughness of bone. Bone 31:1-7
    • (2002) Bone , vol.31 , pp. 1-7
    • Wang, X.1    Shen, X.2    Li, X.3    Agrawal, C.M.4
  • 45
    • 33748955018 scopus 로고    scopus 로고
    • Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls
    • Saito M, Fujii K, Marumo K (2006) Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls. Calcif Tissue Int 79:160-168
    • (2006) Calcif Tissue Int , vol.79 , pp. 160-168
    • Saito, M.1    Fujii, K.2    Marumo, K.3
  • 46
    • 39049133255 scopus 로고    scopus 로고
    • A ductile-to-brittle transition in bone failure due to non-enzymatic collagen-crosslinks - A computational study
    • Siegmund T, Allen MR, Burr D (2007) A ductile-to-brittle transition in bone failure due to non-enzymatic collagen-crosslinks - A computational study. Trans Orthop Res Soc 32:1360
    • (2007) Trans Orthop Res Soc , vol.32 , pp. 1360
    • Siegmund, T.1    Allen, M.R.2    Burr, D.3
  • 47
    • 0142091200 scopus 로고    scopus 로고
    • Effect of hormone replacement therapy on bone quality in early postmenopausal women
    • Paschalis EP, Boskey AL, Kassem M, Eriksen EF (2003) Effect of hormone replacement therapy on bone quality in early postmenopausal women. J Bone Miner Res 18:955-959
    • (2003) J Bone Miner Res , vol.18 , pp. 955-959
    • Paschalis, E.P.1    Boskey, A.L.2    Kassem, M.3    Eriksen, E.F.4
  • 49
    • 0030700363 scopus 로고    scopus 로고
    • FTIR microspectroscopic analysis of human iliac crest biopsies from untreated osteoporotic bone
    • Paschalis EP, Betts F, DiCarlo E, Mendelsohn R, Boskey AL (1997) FTIR microspectroscopic analysis of human iliac crest biopsies from untreated osteoporotic bone. Calcif Tissue Int 61:487-492
    • (1997) Calcif Tissue Int , vol.61 , pp. 487-492
    • Paschalis, E.P.1    Betts, F.2    Dicarlo, E.3    Mendelsohn, R.4    Boskey, A.L.5
  • 52
    • 0036133350 scopus 로고    scopus 로고
    • Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy
    • Sarkar S, Mitlak BH, Wong M, Stock JL, Black DM, Harper KD (2002) Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. J Bone Miner Res 17:1-10
    • (2002) J Bone Miner Res , vol.17 , pp. 1-10
    • Sarkar, S.1    Mitlak, B.H.2    Wong, M.3    Stock, J.L.4    Black, D.M.5    Harper, K.D.6
  • 53
    • 0036119735 scopus 로고    scopus 로고
    • Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs
    • Cummings SR, Karpf DB, Harris F, Genant HK, Ensrud K, LaCroix AZ, Black DM (2002) Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs. Am J Med 112:281-289
    • (2002) Am J Med , vol.112 , pp. 281-289
    • Cummings, S.R.1    Karpf, D.B.2    Harris, F.3    Genant, H.K.4    Ensrud, K.5    Lacroix, A.Z.6    Black, D.M.7
  • 54
    • 0035889539 scopus 로고    scopus 로고
    • A method to assess the proportion of treatment effect explained by a surrogate endpoint
    • Li Z, Meredith MP, Hoseyni MS (2001) A method to assess the proportion of treatment effect explained by a surrogate endpoint. Stat Med 20:3175-3188
    • (2001) Stat Med , vol.20 , pp. 3175-3188
    • Li, Z.1    Meredith, M.P.2    Hoseyni, M.S.3
  • 55
    • 4444238224 scopus 로고    scopus 로고
    • Relationship between changes in bone mineral density and vertebral fracture risk associated with risedronate: Greater increases in bone mineral density do not relate to greater decreases in fracture risk
    • Watts NB, Cooper C, Lindsay R, Eastell R, Manhart MD, Barton IP, van Staa TP, Adachi JD (2004) Relationship between changes in bone mineral density and vertebral fracture risk associated with risedronate: greater increases in bone mineral density do not relate to greater decreases in fracture risk. J Clin Densitom 7:255-261
    • (2004) J Clin Densitom , vol.7 , pp. 255-261
    • Watts, N.B.1    Cooper, C.2    Lindsay, R.3    Eastell, R.4    Manhart, M.D.5    Barton, I.P.6    Van Staa, T.P.7    Adachi, J.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.