메뉴 건너뛰기




Volumn 7, Issue 1, 2008, Pages 83-88

Boron neutron capture therapy for glioblastoma: Is it worth pursuing?

Author keywords

BNCT; Brain tumors; Glioblastoma; Radiotherapy

Indexed keywords

4 BORONOPHENYLALANINE; BORON; EPIDERMAL GROWTH FACTOR RECEPTOR; SODIUM MERCAPTODODECABORATE; UNCLASSIFIED DRUG;

EID: 39049086861     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.1177/153303460800700110     Document Type: Review
Times cited : (10)

References (36)
  • 2
    • 0037693088 scopus 로고    scopus 로고
    • Assessment of the results from the phase I/II boron neutron capture therapy trials at the Brookhaven National Laboratory from a clinician's point of view
    • Diaz, A. Z. Assessment of the results from the phase I/II boron neutron capture therapy trials at the Brookhaven National Laboratory from a clinician's point of view. J Neuro-Oncol 62, 101-109 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 101-109
    • Diaz, A.Z.1
  • 3
    • 0031657111 scopus 로고    scopus 로고
    • Radiobiology with heavy charged particles: A historic review
    • Skarsgard, L. D. Radiobiology with heavy charged particles: a historic review. Phys Med 14 (suppl 1), 1-19 (1998).
    • (1998) Phys Med , vol.14 , Issue.SUPPL. 1 , pp. 1-19
    • Skarsgard, L.D.1
  • 4
    • 84960987433 scopus 로고
    • Neutron capture with boron in the treatment of glioblastoma multiforme
    • Farr, L. E., Sweet, W. H., Robertson, J. S., et al. Neutron capture with boron in the treatment of glioblastoma multiforme. Am J Roentenol Rad Ther Nucl Med 71, 279-291 (1954).
    • (1954) Am J Roentenol Rad Ther Nucl Med , vol.71 , pp. 279-291
    • Farr, L.E.1    Sweet, W.H.2    Robertson, J.S.3
  • 5
    • 20344394447 scopus 로고    scopus 로고
    • Boron neutron capture therapy of cancer: Current status and future prospects
    • Barth, R. F., Coderre, J. A., Vicente, M. G., Blue, T. E. Boron neutron capture therapy of cancer: current status and future prospects. Clin Cancer Res 11, 3987-4002 (2005).
    • (2005) Clin Cancer Res , vol.11 , pp. 3987-4002
    • Barth, R.F.1    Coderre, J.A.2    Vicente, M.G.3    Blue, T.E.4
  • 6
    • 0038031736 scopus 로고    scopus 로고
    • Common challenges and problems in clinical trials of boron neutron capture therapy of brain tumors
    • Gupta, N., Gahbauer, R. A., Blue, T. E., Albertson, B. Common challenges and problems in clinical trials of boron neutron capture therapy of brain tumors. J Neuro-Oncol 62, 197-210 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 197-210
    • Gupta, N.1    Gahbauer, R.A.2    Blue, T.E.3    Albertson, B.4
  • 7
    • 0035890743 scopus 로고    scopus 로고
    • Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: Relevance to neutron capture therapy
    • Smith, D. R., Chandra, S., Barth, R. F., et al. Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: relevance to neutron capture therapy. Cancer Res 61, 8179-8187 (2001).
    • (2001) Cancer Res , vol.61 , pp. 8179-8187
    • Smith, D.R.1    Chandra, S.2    Barth, R.F.3
  • 8
    • 0028625761 scopus 로고
    • Preloading with L-tyrosine increases the uptake of boronophenylalanine in mouse melanoma cells
    • Papaspyrou, M., Feinendegen, L. E., Müller-Gärtner, H. W. Preloading with L-tyrosine increases the uptake of boronophenylalanine in mouse melanoma cells. Cancer Res 54, 6311-6314 (1994).
    • (1994) Cancer Res , vol.54 , pp. 6311-6314
    • Papaspyrou, M.1    Feinendegen, L.E.2    Müller-Gärtner, H.W.3
  • 9
    • 0016584877 scopus 로고
    • Boron neutron capture therapy of cerebral gliomas-II. Utilization of the blood-brain barrier and tumor-specific antigens for the selective concentration of boron in gliomas
    • Tolpin, E. I., Wellum, G. R., Dohan, F. C. Jr, et al. Boron neutron capture therapy of cerebral gliomas-II. Utilization of the blood-brain barrier and tumor-specific antigens for the selective concentration of boron in gliomas. Oncology 32, 223-246 (1975).
    • (1975) Oncology , vol.32 , pp. 223-246
    • Tolpin, E.I.1    Wellum, G.R.2    Dohan Jr, F.C.3
  • 10
    • 0031883597 scopus 로고    scopus 로고
    • Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: Boron concentration correlates with tumor cellularity
    • Coderre, J. A., Chanana, A. D., Joel, D. D., et al. Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: boron concentration correlates with tumor cellularity. Rad Res 149, 163-170 (1998).
    • (1998) Rad Res , vol.149 , pp. 163-170
    • Coderre, J.A.1    Chanana, A.D.2    Joel, D.D.3
  • 11
    • 3042736593 scopus 로고    scopus 로고
    • Accumulation of boron in human malignant glioma cells in vitro is cell type dependent
    • Dahlström, M., Capala, J., Lindström, P., et al. Accumulation of boron in human malignant glioma cells in vitro is cell type dependent. J Neuro-Oncol 68, 199-205 (2004).
    • (2004) J Neuro-Oncol , vol.68 , pp. 199-205
    • Dahlström, M.1    Capala, J.2    Lindström, P.3
  • 12
    • 33847215805 scopus 로고    scopus 로고
    • Boron neutron capture therapy for the treatment of glioblastomas and extracranial tumours: As effective, more effective or less effective than photon irradiation?
    • Barth, R. F., Joensuu, H. Boron neutron capture therapy for the treatment of glioblastomas and extracranial tumours: as effective, more effective or less effective than photon irradiation? Radiother Oncol 82, 119-122 (2007).
    • (2007) Radiother Oncol , vol.82 , pp. 119-122
    • Barth, R.F.1    Joensuu, H.2
  • 13
    • 0038708292 scopus 로고    scopus 로고
    • Rat brain tumor models to assess the efficacy of boron neutron capture therapy: A critical evaluation
    • Barth, R. F., Yang, W., Coderre, J. A. Rat brain tumor models to assess the efficacy of boron neutron capture therapy: a critical evaluation. J Neuro-Oncol 62, 61-74 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 61-74
    • Barth, R.F.1    Yang, W.2    Coderre, J.A.3
  • 14
    • 0038030964 scopus 로고    scopus 로고
    • A critical assessment of boron target compounds for boron neutron capture therapy
    • Hawthorne, M. F., Lee, M. W. A critical assessment of boron target compounds for boron neutron capture therapy. J Neuro-Oncol 62, 33-45 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 33-45
    • Hawthorne, M.F.1    Lee, M.W.2
  • 15
    • 0036606584 scopus 로고    scopus 로고
    • Molecular targeting of the epidermal growth factor receptor for neutron capture therapy of gliomas
    • Barth, R. F., Yang, W., Adams, D. M., et al. Molecular targeting of the epidermal growth factor receptor for neutron capture therapy of gliomas. Cancer Res 62, 3159-3166 (2002).
    • (2002) Cancer Res , vol.62 , pp. 3159-3166
    • Barth, R.F.1    Yang, W.2    Adams, D.M.3
  • 16
    • 0023630565 scopus 로고
    • The Monte Carlo simulation of the biological effect of the 10B(n, alpha)7Li reaction in cells and tissue and its implication for boron neutron capture therapy
    • Gabel, D., Foster, S., Fairchild, R. G. The Monte Carlo simulation of the biological effect of the 10B(n, alpha)7Li reaction in cells and tissue and its implication for boron neutron capture therapy. Rad Res 111, 14-25 (1987).
    • (1987) Rad Res , vol.111 , pp. 14-25
    • Gabel, D.1    Foster, S.2    Fairchild, R.G.3
  • 17
    • 0035098777 scopus 로고    scopus 로고
    • Microdosimetry model for boron neutron capture therapy: I. Determination of microscopic quantities of heavy particles on a cellular scale
    • van Vliet-Vroegindeweij, C., Wheeler, F., Stecher-Rasmussen, F., et al. Microdosimetry model for boron neutron capture therapy: I. Determination of microscopic quantities of heavy particles on a cellular scale. Rad Res 155, 490-497 (2001).
    • (2001) Rad Res , vol.155 , pp. 490-497
    • van Vliet-Vroegindeweij, C.1    Wheeler, F.2    Stecher-Rasmussen, F.3
  • 19
    • 0028297726 scopus 로고
    • Clinical results of long-surviving brain tumor patients who underwent boron neutron capture therapy
    • Hatanaka, H., Nakagawa, Y. Clinical results of long-surviving brain tumor patients who underwent boron neutron capture therapy. Int J Rad Oncol Biol Phys 30, 1061-1066 (1994).
    • (1994) Int J Rad Oncol Biol Phys , vol.30 , pp. 1061-1066
    • Hatanaka, H.1    Nakagawa, Y.2
  • 20
    • 0030935441 scopus 로고    scopus 로고
    • Boron neutron capture therapy. Clinical brain tumor studies
    • Nakagawa, Y., Hatanaka, H. Boron neutron capture therapy. Clinical brain tumor studies. J Neuro-Oncol 33, 105-115 (1997).
    • (1997) J Neuro-Oncol , vol.33 , pp. 105-115
    • Nakagawa, Y.1    Hatanaka, H.2
  • 21
    • 0016737844 scopus 로고
    • A revised boron-neutron capture therapy for malignant brain tumors. II. Interim clinical result with the patients excluding previous treatments
    • Hatanaka, H. A revised boron-neutron capture therapy for malignant brain tumors. II. Interim clinical result with the patients excluding previous treatments. J Neurol 209, 81-94 (1975).
    • (1975) J Neurol , vol.209 , pp. 81-94
    • Hatanaka, H.1
  • 22
    • 0024518397 scopus 로고
    • Fractionation and other clinical considerations in boron neutron capture therapy
    • Durrant, K. R., Hopewell, J. W. Fractionation and other clinical considerations in boron neutron capture therapy. Strahlenther Onkol 165, 231-233 (1989).
    • (1989) Strahlenther Onkol , vol.165 , pp. 231-233
    • Durrant, K.R.1    Hopewell, J.W.2
  • 23
    • 8244247686 scopus 로고
    • Clinical implementation of boron neutron capture therapy in Europe
    • Eds, Amaldi, U, Larsson, B. Amsterdam, Elsevier Science
    • Gabel, D., Sauerwein, W. Clinical implementation of boron neutron capture therapy in Europe. In Hadrontherapy in Oncology, pp. 509-517. Eds., Amaldi, U., Larsson, B. Amsterdam, Elsevier Science (1994).
    • (1994) Hadrontherapy in Oncology , pp. 509-517
    • Gabel, D.1    Sauerwein, W.2
  • 24
    • 0029811117 scopus 로고    scopus 로고
    • Boron neutron capture therapy (BNCT) for high-grade gliomas of the brain: A cautionary note
    • Laramore, G. E., Spence, A. M. Boron neutron capture therapy (BNCT) for high-grade gliomas of the brain: a cautionary note. Int J Rad Oncol Biol Phys 36, 241-246 (1996).
    • (1996) Int J Rad Oncol Biol Phys , vol.36 , pp. 241-246
    • Laramore, G.E.1    Spence, A.M.2
  • 25
    • 0038707548 scopus 로고    scopus 로고
    • Clinical review of the Japanese experience with boron neutron capture therapy and a proposed strategy using epithermal neutron beams
    • Nakagawa, Y., Pooh, K., Kobayashi, T., et al. Clinical review of the Japanese experience with boron neutron capture therapy and a proposed strategy using epithermal neutron beams. J Neuro-Oncol 62, 87-99 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 87-99
    • Nakagawa, Y.1    Pooh, K.2    Kobayashi, T.3
  • 26
    • 0038523780 scopus 로고    scopus 로고
    • Boron neutron capture therapy of brain tumors: Clinical trials at the Finnish facility using boronophenylalanine
    • Joensuu, H., Kankaanranta, L., Seppala, T., et al. Boron neutron capture therapy of brain tumors: clinical trials at the Finnish facility using boronophenylalanine. J Neuro-Oncol 62, 123-134 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 123-134
    • Joensuu, H.1    Kankaanranta, L.2    Seppala, T.3
  • 27
    • 0037847454 scopus 로고    scopus 로고
    • Boron neutron capture therapy for glioblastoma multiforme: Clinical studies in Sweden
    • Capala, J., Stenstam, B. H., Skold, K., et al. Boron neutron capture therapy for glioblastoma multiforme: clinical studies in Sweden. J Neuro-Oncol 62, 135-144 (2003).
    • (2003) J Neuro-Oncol , vol.62 , pp. 135-144
    • Capala, J.1    Stenstam, B.H.2    Skold, K.3
  • 28
    • 0026570684 scopus 로고
    • Selection bias, survival, and brachytherapy for glioma
    • Florell, R. C., Macdonald, D. R., Irish, W. D., et al. Selection bias, survival, and brachytherapy for glioma. J Neurosurg 76, 179-183 (1992).
    • (1992) J Neurosurg , vol.76 , pp. 179-183
    • Florell, R.C.1    Macdonald, D.R.2    Irish, W.D.3
  • 29
    • 0025651304 scopus 로고
    • Results of stereotactic brachytherapy used in the initial management of patients with glioblastoma
    • Loeffler, J. S., Alexander, E., Wen, P. Y., et al. Results of stereotactic brachytherapy used in the initial management of patients with glioblastoma. J Natl Cancer Inst 82, 1918-1921 (1990).
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1918-1921
    • Loeffler, J.S.1    Alexander, E.2    Wen, P.Y.3
  • 30
    • 0035889392 scopus 로고    scopus 로고
    • Implant volume as a prognostic variable in brachytherapy decision-making for malignant gliomas stratified by the RTOG recursive partitioning analysis
    • Videtic, G. M., Gaspar, L. E., Zamorano, L., et al. Implant volume as a prognostic variable in brachytherapy decision-making for malignant gliomas stratified by the RTOG recursive partitioning analysis. Int J Rad Oncol Biol Phys 51, 963-968 (2001).
    • (2001) Int J Rad Oncol Biol Phys , vol.51 , pp. 963-968
    • Videtic, G.M.1    Gaspar, L.E.2    Zamorano, L.3
  • 31
    • 85036938854 scopus 로고    scopus 로고
    • Available at, Accessed January 29, 2007
    • Moss, R., McGarry, D. Boron neutron capture therapy. Available at http://ie.jrc.cec.eu.int/publications/info_sheets_docs/Info%20Sheet%20BNCT.pdf. Accessed January 29, 2007.
    • Boron neutron capture therapy
    • Moss, R.1    McGarry, D.2
  • 32
    • 85036955774 scopus 로고    scopus 로고
    • Henriksson, R., Capala, J., H-Stenstam, B., et al. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase 2 study evaluating a prolonged high dose of boronophenylalanine (BPA). Radiother Oncol 79, 150-157 (2006) (RETRACTED Sep. 2006).
    • Henriksson, R., Capala, J., H-Stenstam, B., et al. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase 2 study evaluating a prolonged high dose of boronophenylalanine (BPA). Radiother Oncol 79, 150-157 (2006) (RETRACTED Sep. 2006).
  • 33
    • 2442652800 scopus 로고    scopus 로고
    • Advantage and limitations of weighting factors and weighted dose quantities and their units in boron neutron capture therapy
    • Rassow, J., Sauerwein, W., Wittig, A., et al. Advantage and limitations of weighting factors and weighted dose quantities and their units in boron neutron capture therapy. Med Phys 31, 1128-1134 (2004).
    • (2004) Med Phys , vol.31 , pp. 1128-1134
    • Rassow, J.1    Sauerwein, W.2    Wittig, A.3
  • 34
    • 85036942113 scopus 로고    scopus 로고
    • Ono K, Ueda S, Oda Y, et al. Boron neutron capture therapy for malignant glioma at Kyoto University Reactor [abstract]. In: Seventh International Symposium on Neutron Capture Therapy for Cancer. Zurich, 4-7 Sept. 1996, pp. 161. Eds., Larsson, B., Crawford, J. (1996).
    • Ono K, Ueda S, Oda Y, et al. Boron neutron capture therapy for malignant glioma at Kyoto University Reactor [abstract]. In: Seventh International Symposium on Neutron Capture Therapy for Cancer. Zurich, 4-7 Sept. 1996, pp. 161. Eds., Larsson, B., Crawford, J. (1996).
  • 35
    • 4143154029 scopus 로고    scopus 로고
    • Current clinical results of the Tsukuba BNCT trial
    • Yamamoto, T., Matsumura, A., Nakai, K., et al. Current clinical results of the Tsukuba BNCT trial. Applied Radiat Isotopes 61, 1089-1093 (2004).
    • (2004) Applied Radiat Isotopes , vol.61 , pp. 1089-1093
    • Yamamoto, T.1    Matsumura, A.2    Nakai, K.3
  • 36
    • 19944430891 scopus 로고    scopus 로고
    • Radiologic findings in patients treated with boron neutron capture therapy for glioblastoma multiforme within EORTC trial 11961
    • Vos, M. J., Turowski, B., Zanella, F. E., et al. Radiologic findings in patients treated with boron neutron capture therapy for glioblastoma multiforme within EORTC trial 11961. Int J Rad Oncol Biol Phys 61, 392-399 (2005).
    • (2005) Int J Rad Oncol Biol Phys , vol.61 , pp. 392-399
    • Vos, M.J.1    Turowski, B.2    Zanella, F.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.