Effects of muscle metabolites on responses of muscle sympathetic nerve activity to mechanoreceptor(s) stimulation in healthy humans

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 2, 2008, Pages

  Cui, Jian ^a   Mascarenhas, Vernon ^a   Moradkhan, Raman ^a   Blaha, Cheryl ^a   Sinoway, Lawrence I ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Autonomic nervous system; Exercise pressor reflex; Muscle afferent

Indexed keywords

ADULT; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; HAND GRIP; HEMODYNAMIC PARAMETERS; HUMAN; HUMAN EXPERIMENT; MALE; MECHANORECEPTOR; MUSCLE INNERVATION; MUSCLE METABOLISM; MUSCLE STRETCHING; NERVE CONDUCTION; NORMAL HUMAN; PRIORITY JOURNAL; SYMPATHETIC NERVE;

ADULT; BLOOD PRESSURE; EXERCISE; FEMALE; HAND STRENGTH; HEART RATE; HUMANS; ISCHEMIA; ISOMETRIC CONTRACTION; LACTIC ACID; MALE; MECHANORECEPTORS; MUSCLE FATIGUE; MUSCLE, SKELETAL; SYMPATHETIC NERVOUS SYSTEM;

EID: 38949177047     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00475.2007     Document Type: Article

References (40)

1. Adreani CM, Hill JM, Kaufman MP. Responses of group III and IV muscle afferents to dynamic exercise. J Appl Physiol 82: 1811-1817, 1997.
2. Adreani CM, Kaufman MP. Effect of arterial occlusion on responses of group III and IV afferents to dynamic exercise. J Appl Physiol 84: 1827-1833, 1998.
3. Batman BA, Hardy JC, Leuenberger UA, Smith MB, Yang QX, Sinoway LI. Sympathetic nerve activity during prolonged rhythmic forearm exercise. J Appl Physiol 76: 1077-1081, 1994.
4. Baum K, Selle K, Leyk D, Essfeld D. Comparison of blood pressure and heart rate responses to isometric exercise and passive muscle stretch in humans. Eur J Appl Physiol Occup Physiol 70: 240-245, 1995.
5. Bell MP, White MJ. Cardiovascular responses to external compression of human calf muscle vary during graded metaboreflex stimulation. Exp Physiol 90: 383-391, 2005.
6. Cui J, Blaha C, Moradkhan M, Gray K, Sinoway L. Muscle sympathetic nerve activity responses to dynamic passive muscle stretch in humans. J Physiol 576: 625-634, 2006.
7. Cui J, Wilson TE, Shibasaki M, Hodges NA, Crandall CG. Baroreflex modulation of muscle sympathetic nerve activity during posthandgrip muscle ischemia in humans. J Appl Physiol 91: 1679-1686, 2001.
8. Cui J, Zhang R, Wilson TE, Crandall CG. Spectral analysis of muscle sympathetic nerve activity in heat-stressed humans. Am J Physiol Heart Circ Physiol 286: H1101-H1106, 2004.
9. Fisher JP, Bell MP, White MJ. Cardiovascular responses to human calf muscle stretch during varying levels of muscle metaboreflex activation. Exp Physiol 90: 773-781, 2005.
10. Gladwell VF, Coote JH. Heart rate at the onset of muscle contraction and during passive muscle stretch in humans: a role for mechanoreceptors. J Physiol 540: 1095-1102, 2002.
11. Halliwill JR. Segregated signal averaging of sympathetic baroreflex responses in humans. J Appl Physiol 88: 767-773, 2000.
12. Hayashi N, Hayes SG, Kaufman MP. Comparison of the exercise pressor reflex between forelimb and hindlimb muscles in cats. Am J Physiol Regul Integr Comp Physiol 281: R1127-R1133, 2001.
13. Hayes SG, Kaufman MP. Gadolinium attenuates exercise pressor reflex in cats. Am J Physiol Heart Circ Physiol 280: H2153-H2161, 2001.
14. Hayes SG, Kaufman MP. MLR stimulation and exercise pressor reflex activate different renal sympathetic fibers in decerebrate cats. J Appl Physiol 92: 1628-1634, 2002.
15. Hayes SG, Kindig AE, Kaufman MP. Comparison between the effect of static contraction and tendon stretch on the discharge of group III and IV muscle afferents. J Appl Physiol 99: 1891-1896, 2005.
16. Hayes SG, Kindig AE, Kaufman MP. Cyclooxygenase blockade attenuates responses of group III and IV muscle afferents to dynamic exercise in cats. Am J Physiol Heart Circ Physiol 290: H2239-H2246, 2006.
17. Herr MD, Imadojemu V, Kunselman AR, Sinoway LI. Characteristics of the muscle mechanoreflex during quadriceps contractions in humans. J Appl Physiol 86: 767-772, 1999.
18. Hill JM, Adreani CM, Kaufman MP. Muscle reflex stimulates sympathetic postganglionic efferents innervating triceps surae muscles of cats. Am J Physiol Heart Circ Physiol 271: H38-H43, 1996.
19. Iwamoto GA, Botterman BR. Peripheral factors influencing expression of pressor reflex evoked by muscular contraction. J Appl Physiol 58: 1676-1682, 1985.
20. Kaufman MP, Hayes SG. The exercise pressor reflex. Clin Auton Res 12: 429-439, 2002.
21. Kaufman MP, Longhurst JC, Rybicki KJ, Wallach JH, Mitchell JH. Effects of static muscular contraction on impulse activity of group III and IV afferents in cats. J Appl Physiol 55: 105-112, 1983.
22. Kaufman MP, Rybicki KJ. Discharge properties of group III and IV muscle afferents: their responses to mechanical and metabolic stimuli. Circ Res 61: I60 -I65, 1987.
23. Kaufman MP, Rybicki KJ, Waldrop TG, Ordway GA. Effect of ischemia on responses of group III and IV afferents to contraction. J Appl Physiol 57: 644-650, 1984.
24. Li J, Sinoway A, Gao Z, Maile M, Pu M, Sinoway L. Muscle mechanoreflex and metaboreflex responses after myocardial infarction in rats. Circulation 110: 3049-3054, 2004.
25. Li J, Sinoway LI. ATP stimulates chemically sensitive and sensitizes mechanically sensitive afferents. Am J Physiol Heart Circ Physiol 283: H2636-H2643, 2002.
26. Mark AL, Victor RG, Nerhed C, Wallin BG. Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ Res 57: 461-469, 1985.
27. McClain J, Hardy JC, Sinoway LI. Forearm compression during exercise increases sympathetic nerve traffic. J Appl Physiol 77: 2612-2617, 1994.
28. McCloskey DI, Mitchell JH. Reflex cardiovascular and respiratory responses originating in exercising muscle. J Physiol 224: 173-186, 1972.
29. Mense S, Meyer H. Bradykinin-induced modulation of the response behaviour of different types of feline group III and IV muscle receptors. J Physiol 389: 49-63, 1988.
30. Middlekauff HR, Chiu J. Cyclooxygenase products sensitize muscle mechanoreceptors in healthy humans. Am J Physiol Heart Circ Physiol 287: H1944-H1949, 2004.
31. Middlekauff HR, Chiu J, Hamilton MA, Fonarow GC, Maclellan WR, Hage A, Moriguchi J, Patel J. Muscle mechanoreceptor sensitivity in heart failure. Am J Physiol Heart Circ Physiol 287: H1937-H1943, 2004.
32. Rotto DM, Kaufman MP. Effect of metabolic products of muscular contraction on discharge of group III and IV afferents. J Appl Physiol 64: 2306-2313, 1988.
33. Rotto DM, Schultz HD, Longhurst JC, Kaufman MP. Sensitization of group III muscle afferents to static contraction by arachidonic acid. J Appl Physiol 68: 861-867, 1990.
34. Seals DR. Sympathetic neural discharge and vascular resistance during exercise in humans. J Appl Physiol 66: 2472-2478, 1989.
35. Sinoway L, Prophet S, Gorman I, Mosher T, Shenberger J, Dolecki M, Briggs R, Zelis R. Muscle acidosis during static exercise is associated with calf vasoconstriction. J Appl Physiol 66: 429-436, 1989.
36. Sinoway LI, Rea RF, Mosher TJ, Smith MB, Mark AL. Hydrogen ion concentration is not the sole determinant of muscle metaboreceptor responses in humans. J Clin Invest 89: 1875-1884, 1992.
37. Stebbins CL, Brown B, Levin D, Longhurst JC. Reflex effect of skeletal muscle mechanoreceptor stimulation on the cardiovascular system. J Appl Physiol 65: 1539-1547, 1988.
38. Vallbo AB, Hagbarth KE, Torebjörk HE, Wallin BG. Somatosensory, proprioceptive and sympathetic activity in human peripheral nerves. Physiol Rev 59: 919-957, 1979.
39. Victor RG, Rotto DM, Pryor SL, Kaufman MP. Stimulation of renal sympathetic activity by static contraction: evidence for mechanoreceptor-induced reflexes from skeletal muscle. Circ Res 64: 592-599, 1989.
40. Williamson JW, Mitchell JH, Olesen HL, Raven PB, Secher NH. Reflex increase in blood pressure induced by leg compression in man. J Physiol 475: 351-357, 1994.