Chorionic enhancer is dispensable for regulated expression of the human renin gene

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 2, 2008, Pages

  Zhou, Xiyou ^a   Sigmund, Curt D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Gene expression; Renin; Transgenic

Indexed keywords

METASTIN; RENIN;

ARTICLE; ARTIFICIAL CHROMOSOME; CELL SPECIFICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; CHORION; CHROMOSOMES, ARTIFICIAL; ENHANCER ELEMENTS (GENETICS); GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; KIDNEY; MICE; MICE, TRANSGENIC; PLACENTA; PROMOTER REGIONS (GENETICS); PROTEINS; RENIN; TRANSGENES;

EID: 38949153407     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00780.2007     Document Type: Article

References (34)

1. Adams DJ, Head GA, Markus MA, Lovicu FJ, van der WL, Kontgen F, Arends MJ, Thiru S, Mayorov DN, Morris BJ. Renin enhancer is critical for control of renin gene expression and cardiovascular function. J Biol Chem 281: 31753-31761, 2006.
2. Baumann H, Wang Y, Richards CD, Jones CA, Black TA, Gross KW. Endotoxin-induced renal inflammatory response. Oncostatin M as a major mediator of suppressed renin expression. J Biol Chem 275: 22014-22019, 2000.
3. de Roux N, Genin E, Carel JC, Matsuda F, Chaussain JL, Milgrom E. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci USA 100: 10972-10976, 2003.
4. Fuchs S, Philippe J, Germain S, Mathieu F, Jeunemaitre X, Corvol P, Pinet F. Functionality of two new polymorphisms in the human renin gene enhancer region. J Hypertens 20: 2391-2398, 2002.
5. Germain S, Bonnet F, Philippe J, Fuchs S, Corvol P, Pinet F. A novel distal enhancer confers chorionic expression on the human renin gene. J Biol Chem 273: 25292-25300, 1998.
6. Harms JF, Welch DR, Miele ME. KISS1 metastasis suppression and emergent pathways. Clin Exp Metastasis 20: 11-18, 2003.
7. Hiden U, Bilban M, Knofler M, Desoye G. Kisspeptins and the placenta: regulation of trophoblast invasion. Rev Endocr Metab Disord 8: 31-39, 2007.
8. Jessen JR, Meng A, McFarlane RJ, Paw BH, Zon LI, Smith GR, Lin S. Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis. Proc Natl Acad Sci USA 95: 5121-5126, 1998.
9. Liu X, Shi Q, Sigmund CD. Interleukin-1β attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1. Cells Endocrinol 147: 6011-6018, 2006.
10. Markus MA, Goy C, Adams DJ, Lovicu FJ, Morris BJ. Renin enhancer is crucial for full response in renin expression to an in vivo stimulus. Hypertension 50: 933-938, 2007.
11. Moore N, Dicker P, O'Brien JK, Stojanovic M, Conroy RM, Treumann A, O'Brien ET, Fitzgerald D, Shields D, Stanton AV. Renin gene polymorphisms and haplotypes, blood pressure, and responses to renin-angiotensin system inhibition. Hypertension 50: 340-347, 2007.
12. Mrowka R, Steege A, Kaps C, Herzel H, Thiele BJ, Persson PB, Bluthgen N. Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity. Nucleic Acids Res 35: 5120-5129, 2007.
13. Nistala R, Sigmund CD. A reliable and efficient method for deleting operational sequences in PACs and BACs. Nucleic Acids Res 30: e41, 2002.
14. Pan L, Black TA, Shi Q, Jones CA, Petrovic N, Loudon J, Kane C, Sigmund CD, Gross KW. Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. J Biol Chem 276: 45530-45538, 2001.
15. Pan L, Glenn ST, Jones CA, Gronostajski RM, Gross KW. Regulation of renin enhancer activity by nuclear factor I and Sp1/Sp3. Biochim Biophys Acta 1625: 280-290, 2003.
16. Pan L, Glenn ST, Jones CA, Gross KW. Activation of the rat renin promoter by HOXD10. PBX1b PREP1, Ets-1, and the intracellular domain of notch. J Biol Chem 280: 20860-20866, 2005.
17. Pan L, Gross KW. Transcriptional regulation of renin: an update. Hypertension 45: 3-8, 2005.
18. Pan L, Jones CA, Glenn ST, Gross KW. Identification of a novel region in the proximal promoter of the mouse renin gene critical for expression. Am J Physiol Renal Physiol 286: F1107-F1115, 2004.
19. Pan L, Wang Y, Jones CA, Glenn ST, Baumann H, Gross KW. Enhancer-dependent inhibition of mouse renin transcription by inflammatory cytokines. Am J Physiol Renal Physiol 288: F117-F124, 2005.
20. Pan L, Xie Y, Black TA, Jones CA, Pruitt SC, Gross KW. An Abd-B class HOX PBX recognition sequence is required for expression from the mouse Ren-1c gene. J Biol Chem 276: 32489-32494, 2001.
21. Sequeira Lopez ML, Pentz ES, Nomasa T, Smithies O, Gomez RA. Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell 6: 719-728, 2004.
22. Shi Q, Gross KW, Sigmund CD. NF-Y antagonizes renin enhancer function by blocking stimulatory transcription factors. Hypertension 38: 332-336, 2001.
23. Shi Q, Gross KW, Sigmund CD. Retinoic acid-mediated activation of the mouse renin enhancer. J Biol Chem 276: 3597-3603, 2001.
24. Simmons DG, Fortier AL, Cross JC. Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol 304: 567-578, 2007.
25. Sinn PL, Davis DR, Sigmund CD. Highly regulated cell-type restricted expression of human renin in mice containing 140 kb or 160 kb P1 phage artificial chromosome transgenes. J Biol Chem 274: 35785-35793, 1999.
26. Takimoto-Ohnishi E, Saito T, Ishida J, Ohnishi J, Sugiyama F, Yagami K, Fukamizu A. Differential roles of renin and angiotensinogen in the feto-maternal interface in the development of complications of pregnancy. Mol Endocrinol 19: 1361-1372, 2005.
27. Talbot D, Collis P, Antoniou M, Vidal M, Grosveld F, Greaves DR. A dominant control region from the human beta-globin locus conferring integration site-independent gene expression. Nature 338: 352-355, 1989.
28. Tamura K, Chen YE, Tanaka Y, Sakai M, Tsurumi Y, Koide Y, Kihara M, Pratt RE, Horiuchi M, Umemura S, Dzau VJ. Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression. Mol Cell Endocrinol 224: 11-20, 2004.
29. Terao Y, Kumano S, Takatsu Y, Hattori M, Nishimura A, Ohtaki T, Shintani Y. Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta. Biochim Biophys Acta 1678: 102-110, 2004.
30. Todorov VT, Desch M, Schmitt-Nilson N, Todorova A, Kurtz A. Peroxisome proliferator-activated receptor-γ is involved in the control of renin gene expression. Hypertension 50: 939-944, 2007.
31. Todorov VT, Volkl S, Friedrich J, Kunz-Schughart LA, Hehlgans T, Vermeulen L, Haegeman G, Schmitz ML, Kurtz A. Role of CREB1 and NF-κB-p65 in the down-regulation of renin gene expression by tumor necrosis factor α. J Biol Chem 280: 24356-24362, 2005.
32. Ying L, Morris BJ, Sigmund CD. Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both CREB-dependent and CREB-independent mechanisms in Calu-6 cells. J Biol Chem 272: 2412-2420, 1997.
33. Yuan W, Pan W, Kong J, Zheng W, Szeto FL, Wong KE, Cohen R, Klopot A, Zhang Z, Li YC. 1,25-dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J Biol Chem 282: 29821-29830, 2007.
34. Zhou X, Davis DR, Sigmund CD. The human renin kidney enhancer is required to maintain baseline renin expression but is dispensable for tissue-specific, cell-specific, and regulated expression. J Biol Chem 281: 35296-35304, 2006.