Synthesis and cytocompatibility of porous chitosan-silicate hybrids for tissue engineering scaffold application

Chemical Engineering Journal

Volumn 137, Issue 1, 2008, Pages 122-128

  Shirosaki, Yuki ^a   Okayama, Tomoyuki ^b   Tsuru, Kanji ^b   Hayakawa, Satoshi ^b   Osaka, Akiyoshi ^b  

^a UNIVERSITY OF PORTO   (Portugal)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Glycidoxypropyltrimethoxysilane (GPTMS); Chitosan; Cytocompatibility; Organic inorganic hybrid; Osteoblastic cell MG63; Scaffold

Indexed keywords

OSTEOBLASTS; PORE SIZE; PORE STRUCTURE; SILICATES; TISSUE ENGINEERING;

CYTOCOMPATIBILITY; GPTMS; ORGANIC-INORGANIC HYBRID;

CHITOSAN;

CHITOSAN; OSTEOBLASTS; PORE SIZE; PORE STRUCTURE; SILICATES; TISSUE ENGINEERING;

EID: 38949146037     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2007.10.012     Document Type: Article

References (17)

1. Tateishi T., Chen G., and Ushida T. Biodegradable porous scaffolds for tissue engineering. J. Artif. Organs 5 (2002) 77-83
2. Lee Y.-K., and Mooney J.D. Hydrogels for tissue engineering. Chem. Rev. 101 (2001) 1869-1879
3. Park S.-N., Park J.-C., Kim H.-O., Song M.-J., and Suh H. Characterization of porous collagne/hyaluronic acid scaffold modified by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide cross-linking. Biomaterials 23 (2002) 1205-1212
4. Kuo C.-K., and Ma P.-X. Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: Part 1. Structure, gelation rate and mechanical properties. Biomaterials 22 (2001) 511-521
5. Widmer M.S., Gupta P.K., Lu L., Meszlenyi R.K., Evans G.R.D., Brandt K., Savel T., Gurlek A., Patrick Jr. C.W., and Mikos A.G. Manufacture of porous biodegradable polymer conduits by an extrusion process for guided tissue regeneration. Biomaterials 19 (1998) 1945-1955
6. Wang Y.-C., Lin M.-C., Wang D.-M., and Hsieh H.-J. Fabrication of a novel porous PGA-chitosan hybrid matrix for tissue engineering. Biomaterials 24 (2003) 1047-1057
7. Park Y.-J., Lee M.-Y., Lee J.-Y., Seol Y.-J., Chung C.-P., and Lee S.-J. Controlled release of platelet-derived growth factor-BB from chondroitin sulfate-chitosan sponge for guided bone regeneration. J. Control. Release 67 (2000) 385-394
8. Lee J.-Y., Nam S.-H., Im S.-Y., Park Y.-J., Lee Y.-M., Seol Y.-J., Chung C.-P., and Lee S.-J. Enhanced bone formation by controlled growth factor delivery from chitosan-based biomaterials. J. Control. Release 78 (2002) 187-197
9. Wan Y., Wu H., and Wen D. Porous-conductive chitosan scaffolds for tissue engineering: 1. Preparation and characterization. Macromol. Biosci. 4 (2004) 882-890
10. Li J., Pan J., Zhang L., Guo X., and Yu Y. Culture of primary rat hepatocytes within porous chitosan scaffolds. J. Biomed. Mater. Res. 67A (2003) 938-943
11. Ren L., Tsuru K., Hayakawa S., and Osaka A. Sol-gel preparation and in vitro deposition of apatite on porous gelatin-siloxane hybrids. J. Non-Cryst. Solid 285 (2001) 116-122
12. Ren L., Tsuru K., Hayakawa S., and Osaka A. Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering. Biomaterials 23 (2002) 4765-4773
13. Shirosaki Y., Tsuru K., Hayakawa S., Osaka A., Lopes M.A., Santos J.D., and Fernandes M.H. In vitro cytocompatibility of MG63 cells on chitosan-organosiloxane hybrids membranes. Biomaterials 26 (2005) 485-493
14. Hua H., Jie W., and Changshengh L. Development of asymmetric gradational-changed porous chitosan membrane for guided periodontal tissue regeneration. Compos. B 38 (2007) 311-316
15. Clover J., and Gowen M. Are MG63 and HOS TE 85 human osteosarcoma cell lines representative models of the osteoblastic phenotype?. Bone 15 (1994) 585-5911
16. Kang H.-W., Tabata Y., and Ikada Y. Fabrication of porous gelatin scaffolds for tissue engineering. Biomaterials 20 (1999) 1339-1344
17. Ho M.-H., Kuo P.-Y., Hsieh H.-J., Hsien T.-Y., Hou L.-T., Lai J.-Y., and Wang D.-M. Preparation of porous scaffolds by using freeze-extraction and freeze-gelation methods. Biomaterials 25 (2004) 129-138