Discovery of a new anilino-3H-pyrrolo[3,2-f]quinoline derivative as potential anti-cancer agent

European Journal of Medicinal Chemistry

Volumn 43, Issue 2, 2008, Pages 429-434

  Via, L Dalla ^a   Gia, O ^a   Gasparotto, V ^a   Ferlin, M G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Antimitotic effect; Antiproliferative activity; DNA interaction; Pyrroloquinoline derivative

Indexed keywords

1 [4 (3H PYRROLO[3,2 F]QUINOLIN 9 YLAMINO)PHENYL]ETHANONE; AMSACRINE; ANILINO 3H PYRROLO[3,2 F]QUINOLINE DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR; INTERCALATING AGENT; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HL 60; COMPLEX FORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; MASS SPECTROMETRY; QUINOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 38949130754     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.04.008     Document Type: Article

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