Use of multiple carboxylates to increase intracellular retention of fluorescent probes following release from cell penetrating fluorogenic conjugates

Bioconjugate Chemistry

Volumn 19, Issue 1, 2008, Pages 50-56

  Li, Xiaoxu ^a,c   Higashikubo, Ryuji ^b   Taylor, John Stephen ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARBOXYLIC ACIDS; CHEMICAL ACTIVATION; CYTOLOGY; ESTERS; FLUOROPHORES; LANTHANUM COMPOUNDS; NUCLEIC ACIDS; PEPTIDES; PROBES; RATE CONSTANTS;

ACTIVATION SYSTEMS; CARBOXYLIC ACID GROUPS; CELL-PENETRATING PEPTIDE; FLUORESCENT PROBES; FLUOROGENICS; HALF LIVES; INTRACELLULAR RETENTION; MEMBRANE-PERMEABLE; REPORTER SYSTEMS; SIMPLE++;

CARBOXYLATION;

ARGININE; BETA ALANINE; CARBOXYLIC ACID DERIVATIVE; CYSTEINE; FLUORESCEIN; FLUORESCENT DYE; THIOL GROUP; VALINE;

AMINO ACID COMPOSITION; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG UPTAKE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL;

EID: 38949127263     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc070079y     Document Type: Article

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