Expression of the Lystbeige mutation is atheroprotective in chow-fed apolipoprotein E-deficient mice

Journal of Lipid Research

Volumn 49, Issue 2, 2008, Pages 429-437

  Petrovan, Ramona J ^a   Yuan, Yuan ^b   Curtiss, Linda K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bone marrow transplantation; Low density lipoprotein receptor deficient mice; Macrophage; Plaque

Indexed keywords

APOLIPOPROTEIN E; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; HYPERLIPIDEMIA; LYSOSOMAL TRAFFICKING GENE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTECTION; REGULATOR GENE; SMOOTH MUSCLE FIBER;

ANIMAL FEED; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; DIETARY FATS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; PROTEINS; RECEPTORS, LDL;

EID: 38949106208     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700410-JLR200     Document Type: Article

References (27)

1. Breslow, J. L. 1996. Mouse models of atherosclerosis. Science. 272: 685-688.
2. Daugherty, A. 2002. Mouse models of atherosclerosis. Am. J. Med. Sci. 323: 3-10.
3. Ishibashi, S., M. S. Brown, J. L. Goldstein, R. D. Gerard, R. E. Hammer, and J. Herz. 1993. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92: 883-893.
4. Ishibashi, S., J. L. Goldstein, M. S. Brown, J. Herz, and D. K. Burns. 1994. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J. Clin. Invest. 93: 1885-1893.
5. Plump, A. S., J. D. Smith, T. Hayek, K. Aalto-Setala, A. Walsh, J. G. Verstuyft, E. M. Rubin, and J. L. Breslow. 1992. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71: 343-353.
6. Zhang, S. H., R. L. Reddick, J. A. Piedrahita, and N. Maeda. 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258: 468-471.
7. Lutzner, M. A., C. T. Lowrie, and H. W. Jordan. 1967. Giant granules in leukocytes of the beige mouse. J. Hered. 58: 299-300.
8. Introne, W., R. E. Boissy, and W. A. Gahl. 1999. Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome. Mol. Genet. Metab. 68: 283-303.
9. Schiller, N. K., W. A. Boisvert, and L. K. Curtiss. 2002. Inflammation in atherosclerosis: lesion formation in LDL receptor-deficient mice with perforin and Lyst(beige) mutations. Arterioscler. Thromb. Vasc. Biol. 22: 1341-1346.
10. -/- mice. J. Lipid Res. 45: 1398-1409.
11. Nakashima, Y., A. S. Plump, E. W. Raines, J. L. Breslow, and R. Ross. 1994. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14: 133-140.
12. Reddick, R. L., S. H. Zhang, and N. Maeda. 1994. Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression. Arterioscler. Thromb. 14: 141-147.
13. Schiller, N. K., N. Kubo, W. A. Boisvert, and L. K. Curtiss. 2001. Effect of gamma-irradiation and bone marrow transplantation on atherosclerosis in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 21: 1674-1680.
14. Kobayashi, M., K. Inoue, E. Warabi, T. Minami, and T. Kodama. 2005. A simple method of isolating mouse aortic endothelial cells. J. Atheroscler. Thromb. 12: 138-142.
15. Dunzendorfer, S., H-K. Lee, K. Soldau, and P. S. Tobias. 2004. TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J. Immunol. 173: 1166-1170.
16. VanderLaan, P. A., C. A. Reardon, and G. S. Getz. 2004. Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators. Arterioscler. Thromb. Vasc. Biol. 24: 12-22.
17. Curtiss, L. K. 2006. Is two out of three enough for ABCG1? Arterioscler. Thromb. Vasc. Biol. 26: 2175-2177.
18. Corti, R., and J. J. Badimon. 2002. Biologic aspects of vulnerable plaque. Curr. Opin. Cardiol. 17: 616-625.
19. Libby, P. 2006. Atherosclerosis: disease biology affecting the coronary vasculature. Am. J. Cardiol. 98: 3Q-9Q.
20. Virmani, R., A. P. Burke, A. Farb, and F. D. Kolodgie. 2002. Pathology of the unstable plaque. Prog. Cardiovasc. Dis. 44: 349-356.
21. Koenig, W., and N. Khuseyinova. 2007. Biomarkers of atherosclerotic plaque instability and rupture. Arterioscler. Thromb. Vasc. Biol. 27: 15-26.
22. Schwartz, S. M., Z. S. Galis, M. E. Rosenfeld, and E. Falk. 2007. Plaque rupture in humans and mice. Arterioscler. Thromb. Vasc. Biol. 27: 705-713.
23. Greaves, D. R., and S. Gordon. 2005. Thematic review series: the immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors. J. Lipid Res. 46: 11-20.
24. Hajra, L., A. I. Evans, M. Chen, S. J. Hyduk, T. Collins, and M. I. Cybulsky. 2000. The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc. Natl. Acad. Sci. USA. 97: 9052-9057.
25. Tedgui, A., and Z. Mallat. 2006. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol. Rev. 86: 515-581.
26. Gu, L., Y. Okada, S. K. Clinton, C. Gerard, G. K. Sukhova, P. Libby, and B. J. Rollins. 1998. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol. Cell. 2: 275-281.
27. Peters, W., and I. F. Charo. 2001. Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: lessons from knockout mice. Curr. Opin. Lipidol. 12: 175-180.