High plasma IgE levels within the Scandinavian wolf population, and its implications for mammalian IgE homeostasis

Molecular Immunology

Volumn 45, Issue 7, 2008, Pages 1976-1980

  Ledin, Anna ^a   Arnemo, Jon M ^b   Liberg, Olof ^c   Hellman, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Canine; Helminthes; IgE; Parasites; Wolf

Indexed keywords

IMMUNOGLOBULIN E;

ADAPTIVE IMMUNITY; ANIMAL CELL; ARTICLE; BASOPHIL; DOG; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; INNATE IMMUNITY; MALE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; WOLF;

AGING; ANIMALS; BLOOD SPECIMEN COLLECTION; FEMALE; HOMEOSTASIS; IMMUNOGLOBULIN E; MALE; MAMMALS; SCANDINAVIA; SKIN; WOLVES;

ANIMALIA; CANIDAE; CANIS FAMILIARIS; MAMMALIA; RODENTIA; VERMES;

EID: 38949105164     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.10.029     Document Type: Article

References (16)

1. Arnemo J.M., and Fahlman A. Biomedical protocols for free-ranging brown bears, gray wolves, wolverines and lynx (2007), Norwegian School of Veterinary Science, Tromsø, Norway. http://www.bearproject.info/pdf/Biomedical_Protocols_SBP_2007.pdf
2. Devalapalli A.P., Lesher A., Shieh K., Solow J.S., Everett M.L., Edala A.S., Whitt P., Long R.R., Newton N., and Parker W. Increased levels of IgE and autoreactive, polyreactive IgG in wild rodents: implications for the hygiene hypothesis. Scand. J. Immunol. 64 (2006) 125-136
3. Hellman L. Regulation of IgE homeostasis, and the identification of potential targets for therapeutic intervention. Biomed. Pharmacother. 61 (2007) 34-49
4. Iancovici Kidon M., Stein M., Geller-Bernstein C., Weisman Z., Steinberg S., Greenberg Z., Handzel Z.T., and Bentwich Z. Serum immunoglobulin E levels in Israeli-Ethiopian children: environment and genetics. Isr. Med. Assoc. J. 7 (2005) 799-802
5. Lanning D.K., Zhai S.K., and Knight K.L. Analysis of the 3′ Cmu region of the rabbit Ig heavy chain locus. Gene 309 (2003) 135-144
6. Ledin A., Bergvall K., Hillbertz N.S., Hansson H., Andersson G., Hedhammar A., and Hellman L. Generation of therapeutic antibody responses against IgE in dogs, an animal species with exceptionally high plasma IgE levels. Vaccine 24 (2006) 66-74
7. Meeusen E.N. Immunology of helminth infections, with special reference to immunopathology. Vet. Parasitol. 84 (1999) 259-273
8. Mitre E., and Nutman T.B. IgE memory: persistence of antigen-specific IgE responses years after treatment of human filarial infections. J. Allergy Clin. Immunol. 117 (2006) 939-945
9. Pullola T., Vierimaa J., Saari S., Virtala A.M., Nikander S., and Sukura A. Canine intestinal helminths in Finland: prevalence, risk factors and endoparasite control practices. Vet. Parasitol. 140 (2006) 321-326
10. Scaglia M., Tinelli M., Revoltella R., Peracino A., Falagiani P., Jayakar S.D., Desmarais J.C., and Siccardi A.G. Relationship between serum IgE levels and intestinal parasite load in African populations. Int. Arch. Allergy Appl. Immunol. 59 (1979) 465-468
11. Serra M.F., Barreto E.O., Silva J.P., Azevedo V., Mota E.M., Pelajo-Machado M., Lucena S., Pires A.L., Carvalho V., Cordeiro R.S., Lenzi H.L., Silva P.M., and Martins M.A. Kinetics of eosinophil and IgE-mast cell changes following infection with Angiostrongylus costaricensis in Wistar rats. Parasite Immunol. 25 (2003) 169-177
12. van Rheede T., Bastiaans T., Boone D.N., Hedges S.B., de Jong W.W., and Madsen O. The platypus is in its place: nuclear genes and indels confirm the sister group relation of monotremes and Therians. Mol. Biol. Evol. 23 (2006) 587-597
13. Vernersson M., Aveskogh M., and Hellman L. Cloning of IgE from the echidna (Tachyglossus aculeatus) and a comparative analysis of epsilon chains from all three extant mammalian lineages. Dev. Comp. Immunol. 28 (2004) 61-75
14. Vernersson M., Aveskogh M., Munday B., and Hellman L. Evidence for an early appearance of modern post-switch immunoglobulin isotypes in mammalian evolution (II); cloning of IgE, IgG1 and IgG2 from a monotreme, the duck-billed platypus, Ornithorhynchus anatinus. Eur. J. Immunol. 32 (2002) 2145-2155
15. Wagner B., Radbruch A., Rohwer J., and Leibold W. Monoclonal anti-equine IgE antibodies with specificity for different epitopes on the immunoglobulin heavy chain of native IgE. Vet. Immunol. Immunopathol. 92 (2003) 45-60
16. Woodburne M.O., Rich T.H., and Springer M.S. The evolution of tribospheny and the antiquity of mammalian clades. Mol. Phylogenet. Evol. 28 (2003) 360-385