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Volumn 117, Issue 1, 2008, Pages 51-58

EP4 agonist inhibits lipopolysaccharide-induced mucus secretion in airway epithelial cells

Author keywords

Cell culture; Goblet cell; Nose; Prostaglandin E2; Rat

Indexed keywords

AEI 329; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN EP4 AGONIST; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

EID: 38949099298     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940811700111     Document Type: Article
Times cited : (14)

References (25)
  • 1
    • 0027446922 scopus 로고
    • Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14
    • Pugin J, Schurer-Maly CC, Leturcq D, Moriarty A, Ulevitch RJ, Tobias PS. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc Natl Acad Sci U S A 1993;90:2744-8.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 2744-2748
    • Pugin, J.1    Schurer-Maly, C.C.2    Leturcq, D.3    Moriarty, A.4    Ulevitch, R.J.5    Tobias, P.S.6
  • 2
    • 0029922504 scopus 로고    scopus 로고
    • Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14
    • Hailman E, Vasselon T, Kelley M, et al. Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14. J Immunol 1996;156:4384-90.
    • (1996) J Immunol , vol.156 , pp. 4384-4390
    • Hailman, E.1    Vasselon, T.2    Kelley, M.3
  • 3
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999;274:10689-92.
    • (1999) J Biol Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 4
    • 4444257589 scopus 로고    scopus 로고
    • A20 inhibits toll-like receptor 2- and 4-mediated interleukin-8 synthesis in airway epithelial cells
    • Gon Y, Asai Y, Hashimoto S, et al. A20 inhibits toll-like receptor 2- and 4-mediated interleukin-8 synthesis in airway epithelial cells. Am J Respir Cell Mol Biol 2004;31:330-6.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 330-336
    • Gon, Y.1    Asai, Y.2    Hashimoto, S.3
  • 5
    • 0038707201 scopus 로고    scopus 로고
    • LPS upregulates mucin and cytokine mRNA expression and stimulates mucin and cytokine secretion in goblet cells
    • Smirnova MG, Guo L, Birchall JP, Pearson JP. LPS upregulates mucin and cytokine mRNA expression and stimulates mucin and cytokine secretion in goblet cells. Cell Immunol 2003;221:42-9.
    • (2003) Cell Immunol , vol.221 , pp. 42-49
    • Smirnova, M.G.1    Guo, L.2    Birchall, J.P.3    Pearson, J.P.4
  • 6
    • 0035313381 scopus 로고    scopus 로고
    • The expression of prostaglandin E receptors EP2 and EP4 and their different regulation by lipopolysaccharide in C3H/HeN peritoneal macrophages
    • Ikegami R, Sugimoto Y, Segi E, et al. The expression of prostaglandin E receptors EP2 and EP4 and their different regulation by lipopolysaccharide in C3H/HeN peritoneal macrophages. J Immunol 2001;166:4689-96.
    • (2001) J Immunol , vol.166 , pp. 4689-4696
    • Ikegami, R.1    Sugimoto, Y.2    Segi, E.3
  • 8
    • 0034638635 scopus 로고    scopus 로고
    • 2 receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils
    • 2 receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. Biochem Biophys Res Commun 2000;278:224-48.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 224-248
    • Yamane, H.1    Sugimoto, Y.2    Tanaka, S.3    Ichikawa, A.4
  • 9
    • 0141727577 scopus 로고    scopus 로고
    • 2 inhibits TNF production in murine bone marrow-derived dendritic cells
    • 2 inhibits TNF production in murine bone marrow-derived dendritic cells. Cell Immunol 2003;223:120-32.
    • (2003) Cell Immunol , vol.223 , pp. 120-132
    • Vassiliou, E.1    Jing, H.2    Ganea, D.3
  • 10
    • 0347991981 scopus 로고    scopus 로고
    • 2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells
    • 2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells. J Leukoc Biol 2003;74:868-79.
    • (2003) J Leukoc Biol , vol.74 , pp. 868-879
    • Jing, H.1    Vassiliou, E.2    Ganea, D.3
  • 11
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya S, Sugimoto Y, Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 1999;79:1193-226.
    • (1999) Physiol Rev , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 12
    • 0032610907 scopus 로고    scopus 로고
    • Monoclonal antibody-detectable carbohydrate epitopes of human nasal secretions are differentially expressed in tissue and diseases
    • Kishioka C, Shimizu T, Fujita K, Ito Y, Majima Y, Sakakura Y. Monoclonal antibody-detectable carbohydrate epitopes of human nasal secretions are differentially expressed in tissue and diseases. Am J Rhinol 1999;13:37-43.
    • (1999) Am J Rhinol , vol.13 , pp. 37-43
    • Kishioka, C.1    Shimizu, T.2    Fujita, K.3    Ito, Y.4    Majima, Y.5    Sakakura, Y.6
  • 13
    • 0029930306 scopus 로고    scopus 로고
    • Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin
    • Shimizu T, Takahashi Y, Kawaguchi S, Sakakura Y. Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin. Am J Respir Crit Care Med 1996;153:1412-8.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1412-1418
    • Shimizu, T.1    Takahashi, Y.2    Kawaguchi, S.3    Sakakura, Y.4
  • 14
    • 0034057718 scopus 로고    scopus 로고
    • Secretory cell differentiation and mucus secretion in cultures of human nasal epithelial cells: Use of a monoclonal antibody to study human nasal mucin
    • Usui S, Shimizu T, Kishioka C, Fujita K, Sakakura Y. Secretory cell differentiation and mucus secretion in cultures of human nasal epithelial cells: use of a monoclonal antibody to study human nasal mucin. Ann Otol Rhinol Laryngol 2000;109:271-7.
    • (2000) Ann Otol Rhinol Laryngol , vol.109 , pp. 271-277
    • Usui, S.1    Shimizu, T.2    Kishioka, C.3    Fujita, K.4    Sakakura, Y.5
  • 15
    • 0041874952 scopus 로고    scopus 로고
    • In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells
    • Shimizu T, Shimizu S, Hattori R, Gabazza EC, Majima Y. In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells. Am J Respir Crit Care Med 2003;168:581-7.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 581-587
    • Shimizu, T.1    Shimizu, S.2    Hattori, R.3    Gabazza, E.C.4    Majima, Y.5
  • 16
    • 0028809831 scopus 로고
    • 2 and selective EP agonists on chemotaxis of human neutrophils
    • 2 and selective EP agonists on chemotaxis of human neutrophils. Br J Pharmacol 1995;116:2903-8.
    • (1995) Br J Pharmacol , vol.116 , pp. 2903-2908
    • Armstrong, R.A.1
  • 17
    • 0000809670 scopus 로고    scopus 로고
    • Effect of cyclo-oxygenase inhibitors and modulators of cyclic AMP formation on lipopolysaccharide-induced neutrophil infiltration in mouse lung
    • Goncalves de Moraes VL, Boris Vargaftig B, Lefort J, Meager A, Chignard M. Effect of cyclo-oxygenase inhibitors and modulators of cyclic AMP formation on lipopolysaccharide-induced neutrophil infiltration in mouse lung. Br J Pharmacol 1996;117:1792-6.
    • (1996) Br J Pharmacol , vol.117 , pp. 1792-1796
    • Goncalves de Moraes, V.L.1    Boris Vargaftig, B.2    Lefort, J.3    Meager, A.4    Chignard, M.5
  • 18
    • 0035073987 scopus 로고    scopus 로고
    • Downregulation of lipopolysaccharide-induced intercellular adhesion molecule-1 expression via EP2/EP4 receptors by prostaglandin E2 in human fibroblasts
    • Noguchi K, Iwasaki K, Shitashige M, et al. Downregulation of lipopolysaccharide-induced intercellular adhesion molecule-1 expression via EP2/EP4 receptors by prostaglandin E2 in human fibroblasts. Inflammation 2001;25:75-81.
    • (2001) Inflammation , vol.25 , pp. 75-81
    • Noguchi, K.1    Iwasaki, K.2    Shitashige, M.3
  • 19
    • 0034037442 scopus 로고    scopus 로고
    • A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production
    • Shimizu T, Hirano H, Majima Y, Sakakura Y. A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production. Am J Respir Crit Care Med 2000;161:1648-54.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1648-1654
    • Shimizu, T.1    Hirano, H.2    Majima, Y.3    Sakakura, Y.4
  • 20
    • 0033764363 scopus 로고    scopus 로고
    • Role of neutrophil elastase in endotoxin-induced mucus hypersecretion in rat nasal epithelium
    • Shimizu T, Takahashi Y, Takeuchi K, Majima Y, Sakakura Y. Role of neutrophil elastase in endotoxin-induced mucus hypersecretion in rat nasal epithelium. Ann Otol Rhinol Laryngol 2000;109:1049-54.
    • (2000) Ann Otol Rhinol Laryngol , vol.109 , pp. 1049-1054
    • Shimizu, T.1    Takahashi, Y.2    Takeuchi, K.3    Majima, Y.4    Sakakura, Y.5
  • 21
    • 0036827039 scopus 로고    scopus 로고
    • Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells
    • Kim YD, Kwon EJ, Park DW, Song SY, Yoon SK, Baek SH. Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells. Mol Pharmacol 2002;62:1112-8.
    • (2002) Mol Pharmacol , vol.62 , pp. 1112-1118
    • Kim, Y.D.1    Kwon, E.J.2    Park, D.W.3    Song, S.Y.4    Yoon, S.K.5    Baek, S.H.6
  • 22
    • 3342951748 scopus 로고    scopus 로고
    • Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling
    • Gray T, Nettesheim P, Loftin C, et al. Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. Mol Pharmacol 2004;66:337-46.
    • (2004) Mol Pharmacol , vol.66 , pp. 337-346
    • Gray, T.1    Nettesheim, P.2    Loftin, C.3
  • 23
    • 0037304183 scopus 로고    scopus 로고
    • PGE2 reduces arachidonic acid release in murine podocytes: Evidence for an autocrine feedback loop
    • Lemieux LI, Rahal SS, Kennedy CR. PGE2 reduces arachidonic acid release in murine podocytes: evidence for an autocrine feedback loop. Am J Physiol Cell Physiol 2003;284:C302-C309.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Lemieux, L.I.1    Rahal, S.S.2    Kennedy, C.R.3
  • 24
    • 18244406799 scopus 로고    scopus 로고
    • Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3
    • Kunikata T, Yamane H, Segi E, et al. Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Nat Immunol 2005;6:524-31.
    • (2005) Nat Immunol , vol.6 , pp. 524-531
    • Kunikata, T.1    Yamane, H.2    Segi, E.3
  • 25
    • 0035149883 scopus 로고    scopus 로고
    • A novel prostaglandin E receptor subtype agonist, ONO-4819, attenuates acute experimental liver injury in rats
    • Kasai K, Sato S, Suzuki K. A novel prostaglandin E receptor subtype agonist, ONO-4819, attenuates acute experimental liver injury in rats. Hepatol Res 2001;21:252-60.
    • (2001) Hepatol Res , vol.21 , pp. 252-260
    • Kasai, K.1    Sato, S.2    Suzuki, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.