A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice

Journal of Endocrinology

Volumn 196, Issue 1, 2008, Pages 79-88

  Sagazio, Alessia ^a,c   Xiao, Xiao ^b   Wang, Zhong ^b,d   Martari, Marco ^a   Salvatori, Roberto ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF CHIETI   (Italy)

^d BROOKLYN HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; DOUBLE STRANDED DNA; GROWTH HORMONE; MESSENGER RNA; PLACEBO; SOMATOMEDIN BINDING PROTEIN 1; GREEN FLUORESCENT PROTEIN; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG MEGADOSE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GROWTH HORMONE DEFICIENCY; IMMUNE RESPONSE; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SINGLE DRUG DOSE; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; ADENO ASSOCIATED VIRUS; AGING; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; BODY COMPOSITION; C57BL MOUSE; GENE VECTOR; GENETICS; GROWTH DISORDER; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE MUTANT; ORGAN SIZE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGING; ANIMALS; BODY COMPOSITION; DEPENDOVIRUS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; GROWTH DISORDERS; GROWTH HORMONE; INJECTIONS, INTRAPERITONEAL; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; ORGAN SPECIFICITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 38849159509     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-07-0312     Document Type: Article

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