Low NaCl intake elevates renal medullary endothelin-1 and endothelin a (ETA) receptor mRNA but not the sensitivity of renal Na+ excretion to ETA receptor blockade in rats

Acta Physiologica

Volumn 192, Issue 3, 2008, Pages 429-442

  Klinger, F ^a   Grimm, R ^a   Steinbach, A ^a   Tanneberger, M ^a   Kunert Keil, C ^a   Rettig, R ^a   Grisk, O ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Angiotensin II; Endothelin; Kidney; Rats; Sodium chloride

Indexed keywords

DARUSENTAN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; LOSARTAN; MESSENGER RNA; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DEVICE; DRUG MECHANISM; GENE EXPRESSION; KIDNEY BLOOD FLOW; KIDNEY MEDULLA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SALT INTAKE; SODIUM BALANCE; SODIUM URINE LEVEL; SPRAGUE DAWLEY RAT; TELEMETRY;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; ENDOTHELIN-1; GENE EXPRESSION; KIDNEY MEDULLA; LOSARTAN; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RENAL CIRCULATION; RNA, MESSENGER; SODIUM; SODIUM CHLORIDE, DIETARY;

EID: 38849159257     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2007.01751.x     Document Type: Article

References (47)

1. Abadie, L., Blazy, I., Roubert, P. et al. 1996. Decrease in endothelin-1 renal receptors during the 1st month of life in the rat. Pediatr Nephrol 10, 185 189.
2. Abassi, Z.A., Klein, H., Golomb, E. Keiser, H.R. 1993. Urinary endothelin: a possible marker of renal damage. Am J Hypertens 6, 1046 1054.
3. Alexander, B.T., Cockrell, K.L., Rinewalt, A.N., Herrington, J.N. Granger, J.P. 2001. Enhanced renal expression of preproendothelin mRNA during chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol 280, R1388 R1392.
4. Bagnall, A.J., Kelland, N.F., Gulliver-Sloan, F. et al. 2006. Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt. Hypertension 48, 286 293.
5. Ballew, J.R. Fink, G.D. 2001. Role of ET(A) receptors in experimental ANG II-induced hypertension in rats. Am J Physiol Regul Integr Comp Physiol 281, R150 R154.
6. Barton, M., Shaw, S., d'Uscio, L.V., Moreau, P. Luscher, T.F. 1997. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun 238, 861 865.
7. Boesen, E.I. Pollock, D.M. 2007. Acute increases of renal medullary osmolality stimulate endothelin release from the kidney. Am J Physiol Renal Physiol 292, F185 F191.
8. Chen-Hsien, C., Yung-Ho, H., Yuh-Mou, S. et al. 2006. Src homolgy 2-containing phophotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor transactivation in rat renal tubular cell NRK-52E. Pfluegers Arch Eur J Physiol 452, 16 24.
9. De Jesus-Ferreira, M.C. Bailly, C. 1997. Luminal and basolateral endothelin inhibit chloride reabsorption in the mouse thick ascending limb via a Ca(2+)-independent pathway. J Physiol 505, 749 758.
10. 125I-endothelin binding in rat kidney following in vivo labelling. Am J Physiol Renal Physiol 267, F845 F852.
11. Fattal, I., Abassi, Z., Ovcharenko, E. et al. 2004. Effect of dietary sodium intake on the expression of endothelin-converting enzyme in the renal medulla. Nephron Physiol 98, 89 96.
12. Feron, O., Salamone, S. Godfraind, T. 1995. Influence of saltloading on the cardiac and renal preproendothelin-1 mRNA expression in stroke-prone spontaneously hypertensive rats. Biochem Biophys Res Commun 209, 161 166.
13. Firth, J.D., Schricker, P.J. Kurtz, A. 1995. Expression of endothelins 1 and 3 in the rat kidney. Am J Physiol Renal Physiol 269, F522 F528.
14. Frey, B., Grisk, O., Bandelow, N., Wussow, S., Bie, P. Rettig, R. 2000. Sodium homeostasis in transplanted rats with a spontaneously hypertensive rat kidney. Am J Physiol Regul Integr Comp Physiol 279, R1099 R1104.
15. Ge, Y., Bagnall, A., Stricklett, P.K. et al. 2006. Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. Am J Physiol Renal Physiol 291, F1274 F1280.
16. Granger, J.P. 2003. Endothelin. Am J Physiol Regul Integr Comp Physiol 285, R298 R301.
17. Grisk, O., Rose, H.J., Lorenz, G. Rettig, R. 2002. Sympathetic-renal interaction in chronic arterial pressure control. Am J Physiol Regul Integr Comp Physiol 283, R441 R450.
18. Grisk, O., Lother, U., Gabriels, G. Rettig, R. 2005. Influence of neonatal sympathectomy on proximal renal resistance artery function in spontaneously hypertensive rats. Pfluegers Arch Eur J Physiol 449, 364 371.
19. Gross, V., Kurth, T.M., Skelton, M.M., Mattson, D.L. Cowley, A.W. 1998. Effects of daily sodium intake and ANG II on cortical and medullary renal blood flow in conscious rats. Am J Physiol Regul Integr Comp Physiol 274, R1317 R1323.
20. Guo, X. Yang, T. 2006. Endothelin B receptor antagonism in the rat renal medulla reduces urine flow rate and sodium excretion. Exp Biol Med 231, 1001 1005.
21. Gurbanov, K., Rubinstein, I., Hoffman, A., Abassi, Z., Better, O.S. Winaver, J. 1996. Differential regulation of renal regional blood flow by endothelin-1. Am J Physiol Renal Physiol 271, F1166 F1172.
22. Hercule, H.C. Oyekan, A.O. 2000. Role of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal haemodynamics in rats. Am J Physiol Regul Integr Comp Physiol 279, R2132 R2141.
23. Herrera, M. Garvin, J.L. 2005. A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. Am J Physiol Renal Physiol 288, F58 F64.
24. Hocher, B., Kalk, P., Slowinski, T. et al. 2003. ETA receptor blockade induces tubular cell proliferation and cyst growth in rats with polycystic kidney disease. J Am Soc Nephrol 14, 367 376.
25. Hoffman, A., Abassi, Z.A., Brodsky, S., Ramadan, R. Winaver, J. 2000. Mechanisms of big endothelin-1-induced diuresis and natriuresis : role of ET(B) receptors. Hypertension 35, 732 739.
26. Inscho, E.W., Imig, J.D., Cook, A.K. Pollock, D.M. 2005. ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. Br J Pharmacol 146, 1019 1026.
27. Just, A., Olson, A.J. Arendshorst, W.J. 2004. Dual constrictor and dilator actions of ET(B) receptors in the rat renal microcirculation: interactions with ET(A) receptors. Am J Physiol Renal Physiol 286, F660 F668.
28. Klein, H., Abassi, Z. Keiser, H.R. 1995. Effects of angiotensin II and phenylephrine on urinary endothelin in normal female volunteers. Metabolism 44, 115 118.
29. Kohan, D.E. 2006. The renal medullary endothelin system in control of sodium and water excretion and systemic blood pressure. Curr Opin Nephrol Hypertens 15, 34 40.
30. Martus, W., Kim, D., Garvin, J.L. Beierwaltes, W.H. 2005. Commercial rodent diets contain more sodium than rats need. Am J Physiol Renal Physiol 288, F428 F431.
31. McCormick, C.P., Rauch, A.L. Buckalew, V.-M.J. 1989. Differential effect of dietary salt on renal growth in Dahl salt-sensitive and salt-resistant rats. Hypertension 13, 122 127.
32. Michell, A.R. 1994. Salt, hypertension and renal disease: comparative medicine, models and real diseases. Postgrad Med J 70, 686 694.
33. Modesti, P.A., Cecioni, I., Migliorini, A. et al. 1998. Increased renal endothelin formation is associated with sodium retention and increased free water clearance. Am J Physiol Heart Circ Physiol 275, H1070 H1077.
34. Ong, A.C., Jowett, T.P., Firth, J.D., Burton, S., Karet, F.E. Fine, L.G. 1995. An endothelin-1 mediated autocrine growth loop involved in human renal tubular regeneration. Kidney Int 48, 390 401.
35. Pallone, T.L., Turner, M.R., Edwards, A. Jamison, R.L. 2003. Counter current exchange in the renal medulla. Am J Physiol Regul Integr Comp Physiol 284, R1153 R1175.
36. Plato, C.F., Pollock, D.M. Garvin, J.L. 2000. Endothelin inhibits thick ascending limb chloride flux via ET(B) receptor-mediated NO release. Am J Physiol Renal Physiol 279, F326 F333.
37. Pollock, D.M. Pollock, J.S. 2001. Evidence for endothelin involvement in the response to high salt. Am J Physiol Renal Physiol 281, F144 F150.
38. Pollock, D.M., Allcock, G.H., Krishnan, A., Dayton, B.D. Pollock, J.S. 2000. Upregulation of endothelin B receptors in kidneys of DOCA-salt hypertensive rats. Am J Physiol Renal Physiol 278, F279 F286.
39. Sasser, J.M., Pollock, J.S. Pollock, D.M. 2002. Renal endothelin in chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol 283, R243 R248.
40. Simon, G. 2004. Pathogenesis of structural vascular changes in hypertension. J Hypertens 22, 3 10.
41. Taylor, T.A., Gariepy, C.E., Pollock, D.M. Pollock, J.S. 2003. Unique endothelin receptor binding in kidneys of ETB receptor deficient rats. Am J Physiol Regul Integr Comp Physiol 284, R674 R681.
42. Terada, Y., Tomita, K., Nonoguchi, H. Marumo, F. 1992. Different localization of two types of endothelin receptor mRNA in microdissected rat nephron segments using reverse transcription and polymerase chain reaction assay. J Clin Invest 90, 107 112.
43. Vanni, S., Polidori, G., Cecioni, I., Serni, S., Carini, M. Modesti, P.A. 2002. ET(B) receptor in renal medulla is enhanced by local sodium during low salt intake. Hypertension 40, 179 185.
44. Vassileva, I., Mountain, C. Pollock, D.M. 2004. Functional role of ETB receptors in the renal medulla. Hypertension 41, 1359 1363.
45. Winaver, J., Abassi, S., Grenn, J. Skorecki, K.L. 2000. Control of extracellular fluid volume and the pathophysiology of edema formation. In : B.M. Brenner (ed.) The Kidney, pp. 795 865. Saunders, Philadelphia, PA.
46. Yamamoto, T., Hirohama, T. Uemura, H. 2002. Endothelin B receptor-like immunoreactivity in podocytes of the rat kidney. Arch Histol Cytol 65, 245 250.
47. Yukimura, T., Notoya, M., Mizojiri, K. et al. 1996. High resolution localization of endothelin receptors in rat renal medulla. Kidney Int 50, 135 147.