Expression patterns of adhesion molecules P-selectin, von Willebrand factor and PECAM-1 in lungs: A comparative study in cases of burn shock and hemorrhagic shock

Forensic Science International

Volumn 175, Issue 2-3, 2008, Pages 102-106

  Weis, Andreas ^a   Bohnert, Michael ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Burn shock; Burns; Fire fatalities; Hemorrhagic shock; Lung; P selectin; PECAM 1; von Willebrand factor

Indexed keywords

CD31 ANTIGEN; PADGEM PROTEIN; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; BURN SHOCK; CELL ACTIVATION; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FORENSIC PATHOLOGY; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE FUNCTION; LEUKOCYTE MIGRATION; LUNG; LUNG BLOOD VESSEL; LUNG PARENCHYMA; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; THROMBOCYTE FUNCTION; VASCULAR ENDOTHELIUM;

EID: 38849134828     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2007.05.015     Document Type: Article

References (35)

1. Herndon D.N. Total Burn Care (2002), Saunders, London
2. Loick H.M., Traber L.D., Stothert J.C., Herndon D.N., and Traber D.L. Smoke inhalation causes a delayed increase in airway blood flow to primarily uninjured lung areas. Intensive Care Med. 21 (1995) 326-333
3. Soejima K., Schmalstieg F.C., Sakurai H., and Traber D.L. Pathophysiological analysis of combined burn and smoke inhalation injuries in sheep. Am. J. Physiol. Lung Cell Mol. Phyiol. 280 (2001) 1233-1241
4. Westphal M., Morita N., Enkhbaatar P., Murakami K., Traber L., and Traber D.L. Acute effects of combined burn and smoke inhalation injury on carboxyhemoglobin formation, tissue oxygenation, and cardiac performance. Biochem. Biophys. Res. Commun. 317 (2004) 945-949
5. Cox R.A., Burke A.S., Oliveras G., Enkhbaatar P., Traber L.D., Zwischenberger J.B., Jeschke M.G., Schmalstieg F.C., Herndon D.N., Traber D.L., and Hawkins H.K. Acute bronchial obstruction in sheep: histopathology and gland cytokine expression. Exp. Lung Res. 31 (2005) 819-837
6. Traber D.L., Herndon D.N., and Soejima K. The pathophysiology of inhalation injury. In: Herndon D.N. (Ed). Total Burn Care (2002), Saunders, London 221-231
7. Traber D.L., and Sherwood E.R. The systemic inflammatory response syndrome. In: Herndon D.N. (Ed). Total Burn Care (2002), Saunders, London 257-270
8. Bohnert M., Werner C.R., and Pollak S. Problems associated with the diagnosis of vitality in burned bodies. Forensic Sci. Int. 135 (2003) 197-205
9. Brinkmann B., Kleiber M., Koops E., and Püschel K. Vitale Reaktionen bei akutem Verbrühungstod. Z. Rechtsmed. 83 (1979) 1-16
10. Janssen W. Injuries caused by heat and cold. In: Janssen W. (Ed). Forensic Histopathology (1984), Springer, Berlin 234-260
11. Fineschi V., D'Errico S., Neri M., Panarese F., Ricci P., and Turillazzi E. Heat stroke in an incubator: an immunohistochemical study in a fatal case. Int. J. Legal Med. 119 (2005) 94-97
12. Shoji T. Demonstration of heat shock protein, ubiquitin, in fire death autopsy cases by immunohistochemical study (in Japanese). Nippon Hoigaku Zasshi 51 (1997) 70-76
13. Nogami M., Takatsu A., Endo N., and Ishiyama I. Immunohistochemical localization of heat shock protein 70 in the human medulla oblongata in forensic autopsies. Legal Med. 1 (1999) 198-203
14. Quan L., Zhu B.L., Oritani S., Ishida K., Fujita M.Q., and Maeda H. Intranuclear ubiquitin immunoreactivity in the pigmented neurons of the substantia nigra in fire fatalities. Int. J. Legal Med. 114 (2001) 310-315
15. Marschall S., Rothschild M.A., and Bohnert M. Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims. Int. J. Legal Med. 120 (2006) 355-359
16. Kibayashi K., and Shojo H. Heat-induced immunoreactivity of tau protein in neocortical neurons of fire fatalities. Int. J. Legal Med. 117 (2003) 282-286
17. Stein M.D., Herndon D.N., Stevens M., Traber L.D., and Traber D.L. Production of chemotactic factors and lung cell changes following smoke inhalation in a sheep model. J. Burn Care Rehabil. 7 (1986) 117-121
18. Muller W.A. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol. 24 (2003) 327-334
19. Muller W.A., Weigl S.A., Deng X., and Phillips D.M. PECAM-1 is required for transendothelial migration of leukocytes. J. Exp. Med. 178 (1993) 449-460
20. Saukko P.J., and Knight B. Knight's Forensic Pathology (2004), Arnold, London
21. McEver R.P. Adhesive interactions of leukocytes, platelets and the vessel wall during hemostasis and inflammation. Thromb. Haemost. 86 (2001) 746-756
22. Merten M., and Thiagarajan P. P-selectin expression on platelets determines size and stability of platelet aggregates. Circulation 102 (2000) 1931-1936
23. Buttrum S.M., Hatton R., and Nash G.B. Selectin-mediated rolling of neutrophils on immobilized platelets. Blood 82 (1993) 1165-1174
24. Chandra A., Katahira J., Schmalstieg F.C., Murakami K., Enkhbaatar P., Cox R.A., Hawkins H.K., Traber L.D., Herndon D.N., and Traber D.L. P-selectin blockade fails to improve acute lung injury in sheep. Clin. Sci. 104 (2003) 313-321
25. Doerschuk C.M., Quinlan W.M., and Doyle N.A. The role of P-selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice. J. Immunol. 157 (1996) 4609-4614
26. Mulligan M.S., Paulson J.C., De Frees S., Zheng Z.L., Lowe J.B., and Ward P.A. Protective effects of oligosaccarides in P-selectin-dependent lung injury. Nature 364 (1993) 149-151
27. Andre P., Denis C.V., Ware J., Saffaripour S., Hynes R.O., Ruggeri Z.M., and Wagner D.D. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood 96 (2000) 3322-3328
28. Christofidou-Solomidou M., Nakada M., Williams J., Muller W., and DeLisser H. Neutrophil platelet endothelial cell adhesion molecule-1 participates in neutrophil recruitment at inflammatory sites and is down-regulated after leukocyte extravasation. J. Immunol. 158 (1997) 4872-4878
29. Mamdouh Z., Chen X., Pierini L.M., Maxfield F.R., and Muller W.A. Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature 421 (2003) 748-753
30. Scholz D., and Schaper J. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) is localized over the entire plasma membrane of endothelial cells. Cell Tissue Res. 290 (1997) 623-631
31. Stewart R.J., Kashour T.S., and Marsden P.A. Vascular endothelial platelet endothelial cell adhesion molecule-1 (PECAM-1) expression is decreased by TNF-alpha and IFN-gamma. J. Immunol. 156 (1996) 1221-1228
32. Schwacha M.G. Macrophages and post-burn immune dysfunction. Burns 29 (2003) 1-14
33. Schwacha M.G., and Chaudry I.H. The cellular basis of post-burn immunosuppression: macrophages and mediators. Int. J. Mol. Med. 10 (2002) 239-243
34. Settle J.A.D. Burns. In: Mason J.K., and Purdue B.N. (Eds). The Pathology of Trauma (2000), Arnold, London 211-229
35. Bone R.C. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation. Crit. Care Med. 24 (1996) 163-172