Contribution of bronchial biopsies in the evaluation of pathogenesis and progression of COPD

Monaldi Archives for Chest Disease - Pulmonary Series

Volumn 67, Issue 4, 2007, Pages 229-233

  Magno, Francesca ^a   Di Stefano, A ^b  

^a UNIVERSITY OF PALERMO   (Italy)

^b IRCCS   (Italy)

Author keywords

Bronchial biopsies; COPD; Inflammatory cells

Indexed keywords

3 NITROTYROSINE; CD11B ANTIGEN; COLLAGEN; GAMMA INTERFERON; HERMES ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOPEROXIDASE; STAT4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

BRONCHUS BIOPSY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL MIGRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE COURSE; DISEASE SEVERITY; HUMAN; IMMUNOREACTIVITY; INFLAMMATORY CELL; LEUKOCYTE ACTIVATION; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; NEUTROPHILIA; PATHOGENESIS; PHENOTYPE; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 38849100288     PISSN: 11220643     EISSN: 2465101X     Source Type: Journal    
DOI: 10.4081/monaldi.2007.479     Document Type: Review

References (33)

1. Pauwels RA, Buist AS, Calverley PMA, Jenkins CR, Hurd SS, on behalf of the GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of Chronic Obstructive Pulmonary Disease. NHLBI/WHO Global initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001; 163: 1256-276.
2. The COPD guidelines group of the standards of care committee of the BTS. BTS guidelines for the management of chronic obstructive pulmonary disease. Thorax 1997; 52: S1-S28.
3. Tetley, T. D. Inflammatory Cells and Chronic Obstructive Pulmonary Disease. Inflammation & Allergy 2005, 6: 607-618.
4. Ollerenshaw SL, Woolcock AJ. Characteristics of the inflammation in biopsies from large airways of subjects with asthma and subjects with chronic airflow limitation. Am Rev Respir Dis 1992; 145: 922-27.
5. Vignola AM, Chanez P, Chiappara, et al. Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med 1997; 156: 591-9.
6. Di Stefano A, Capelli A, Lusuardi M, et al. Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med 1998; 158: 1277-85.
7. Di Stefano A, Capelli A, Lusuardi M, et al. Decreased T-lymphocyte infiltration in bronchial biopsies of subjects with severe chronic obstructive pulmonary disease. Clin Exp Allergy 2001; 31: 893-902.
8. Saetta M, Turato G, Maestrelli P, Mapp CE, Fabbri LM. Cellular and structural bases of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 163: 1304-9.
9. Barnes PJ. Chronic obstructive pulmonary disease. N Engl J Med 2000; 343: 269-80.
10. Sutherland ER, Martin RJ. Airway inflammation in chronic obstructive pulmonary disease: Comparisons with asthma. J Allergy Clin Immunol 2003; 112: 819-27.
11. Di Stefano A, Caramori G, Ricciardolo FLM, Capelli A, Adcock IM, Donner CF. Cellular and molecular mechanisms in chronic obstructive pulmonary disease: an overview. Clin Exp Allergy 2004; 34:1156-67.
12. Di Stefano A, Maestrelli P, Roggeri A, et al. Upregulation of adhesion molecules in the bronchial mucosa of subjects with obstructive chronic bronchitics. Am J Respir Crit Care Med 1994; 149: 803-10.
13. Di Stefano A, Caramori G, Oates T, et al. Increased expression of nuclear factor-kB in bronchial biopsies from smokers and patients with COPD. Eur Respir J 2002; 20: 556-63.
14. O'Shaughmessy TC, Ansari TW, Barnes NC, Jeffery PK. Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1. Am J Respir Crit Care Med 1997; 155: 852-7.
15. Amadori A, Zamarchi R, De Silvestro G, et al. Genetic control of the CD4/CD8 T-cell ratio in humans. Nature Medicine 1995; 1: 1279-83.
16. Costabel U, Maier K, Teschler H, Wang YM. Local immune components in chronic obstructive pulmonary disease. Respiration 1992; 59: 17-19.
17. Hughes DA, Haslam PL, Townsend PJ, Turner-Warwick M. Numerical and functional alterations in circulatory lymphocytes in cigarette smokers. Clin Exp Immunol 1985; 61: 459-66.
18. Gosman MM, Willemse BW, Jansen DF, et al. Groningen and Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group. Increased number of B-cells in bronchial biopsies in COPD. Eur Respir J. 2006; 27: 60-4.
19. Schulz C, Wolf K, Harth M, Kratzel K, Kunz-Schughart L, Pfeifer M. Expression and release of interleukin-8 by human bronchial epithelial cells from patients with chronic obstructive pulmonary disease, smokers, and never-smokers. Respiration 2003; 70: 254-61.
20. Stanescu D, Sanna A, Veriter C, et al. Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils. Thorax 1996; 51: 267-71.
21. Balzano G, Stefanelle F, Iorio C, et al. Eosinophilic inflammation in stable chronic obstructive pulmonary disease. Relationship with neutrophils and airway function. Am J Respir Crit Care Med 1999; 160: 1486-92.
22. Capelli A, Di Stefano A, Gnemmi I, et al. Increased MCP-1 and MIP-1 beta in hronchoalveolar lavage fluid of chronic bronchitics. Eur Respir J 1999; 14: 160-5.
23. Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerkin M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140: 1527-37.
24. Magno F, Sivverini G, Gnemmi I, et al. Epithelial overexpression of Intefleukin-8 in bronchial biopsies from patients with COPD. Eur Respir J 2006; 28: 673S.
25. Suzuki T, Yamaya M, Sekizawa K, et al. Bafilomycin A1 inhibits rhinovirus infection in human airway epithelium: effects on endosome and ICAM-1. Am J Physiol Lung Cell Mol Physiol 2001; 280: L1115-L1127.
26. Di Stefano A, Caramori G, Capelli A, et al. Increased activation of STAT4 in bronchial biopsies from smokers with COPD. Am J Respir Crit Care Med 2003; 167: A159.
27. Thierfelder WE, van Deursen JM, Yamamoto K, et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996; 382: 171-4.
28. Bacon CM, Petricoin III EF, Ortaldo JR, et al. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci 1995; 92: 7307-11.
29. Ricciardolo FLM and Di Stefano A. Smoking-induced corticosteroid resistance in asthma: "the nitrosative stress hypothesis". Am J Respir Crit Care Med 2004; 169: 1252-3.
30. Ricciardolo FLM, Caramori G, Ito K, et al. Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology 2005, 116: 1028-1035.
31. Yoshikawa T, Dent G, Ward J, et al. Impaired neutrophil chemotaxis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 175: 473-9.
32. Rytila P, Plataki M, Bucchieri F, et al. Airway neutrophilia in COPD is not associated with increased neutrophil survival. Eur Respir J 2006; 28:1163-9.
33. Di Stefano A, Magno F, Gnemmi I, et al. Increased neutrophil adhesion in bronchial biopsies from patients with severe COPD. Eur Respir J 2007; 30: 136S.