New 7,8-benzoflavanones as potent aromatase inhibitors: Synthesis and biological evaluation

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 3, 2008, Pages 1474-1480

  Yahiaoui, Samir ^a   Fagnere, Catherine ^a   Pouget, Christelle ^a   Buxeraud, Jacques ^a   Chulia, Albert José ^a  

^a UNIVERSITÉ DE LIMOGES   (France)

Author keywords

7,8 Benzoflavanones; Aromatase inhibitors; Breast cancer; Flavonoids

Indexed keywords

3' CYANO 7,8 BENZOFLAVANONE; 4' HYDROXY 7,8 BENZOFLAVANONE; 7,8 BENZO 3' HYDROXYFLAVANONE; 7,8 BENZO 4' CYANOFLAVANONE; 7,8 BENZOFLAVANONE; AROMATASE INHIBITOR; BENZOFLAVONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

AROMATASE INHIBITORS; BENZENE; CYCLIZATION; FLAVANONES; HUMANS; HYDROGEN BONDING; MICROSOMES; MOLECULAR STRUCTURE; NITRILES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 38849089406     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.057     Document Type: Article

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