Evaluation of radioiodinated (2S,αS)-2-(α-(2-iodophenoxy)benzyl)morpholine as a radioligand for imaging of norepinephrine transporter in the heart

Nuclear Medicine and Biology

Volumn 35, Issue 2, 2008, Pages 213-218

  Kiyono, Yasushi ^a,c   Sugita, Taku ^b   Ueda, Masashi ^c   Kawashima, Hidekazu ^b   Kanegawa, Naoki ^b   Kuge, Yuji ^b   Fujibayashi, Yasuhisa ^a   Saji, Hideo ^b  

^a UNIVERSITY OF FUKUI   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

(S,S) IPBM; Heart; Norepinephrine transporter; Radioiodination; SPECT; Sympathetic nervous function

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; 2 [ALPHA (2 IODOPHENOXY)BENZYL]MORPHOLINE I 125; DESIPRAMINE; DOPAMINE TRANSPORTER; FLUOXETINE; NISOXETINE; NORADRENALIN TRANSPORTER; RADIOLIGAND; REBOXETINE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; VANOXERINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; HEART; HEART MUSCLE FIBER MEMBRANE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PLASMA CLEARANCE; RAT;

ANIMALS; BINDING, COMPETITIVE; DESIPRAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; FLUOXETINE; HEART; IODINE RADIOISOTOPES; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; MORPHOLINES; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PIPERAZINES; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; TISSUE DISTRIBUTION;

EID: 38849088643     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2007.11.006     Document Type: Article

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