Simple and sensitive method for quantification of low tobramycin concentrations in human plasma using HPLC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 257-262

  Attema de Jonge, Milly E ^a   Bekkers, Judith M ^a   Oudemans van Straaten, Heleen M ^a   Sparidans, Rolf W ^b   Franssen, Eric J F ^a  

^a Onze Lieve Vrouwe Gasthuis ^*  (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

HPLC MS MS; Selective decontamination of the digestive tract; Sisomicin; Tobramycin

Indexed keywords

ANTIBIOTICS; PATIENT MONITORING; PROTEINS; SENSITIVITY ANALYSIS;

DIGESTIVE TRACT; SELECTIVE DECONTAMINATION; SISOMICIN; TOBRAMYCIN;

PLASMA (HUMAN);

ACETONITRILE; TOBRAMYCIN;

ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DIGESTIVE SYSTEM; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TOBRAMYCIN;

EID: 38749142900     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.12.008     Document Type: Article

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