Loss of the PTCH1 gene locus in cardiac fibroma

Cardiovascular Pathology

Volumn 17, Issue 2, 2008, Pages 93-97

  Scanlan, David ^a   Radio, Stanley J ^a   Nelson, Marilu ^a   Zhou, Ming ^a   Streblow, Renae ^a   Prasad, Vinay ^b   Reyes, Christine ^c   Perry, Deborah ^c   Fletcher, Scott ^c   Bridge, Julia A ^a,d  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b ARKANSAS CHILDREN S HOSPITAL   (United States)

^c Children's Hospital Omaha   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Cardiac fibroma; Gorlin syndrome; PTCH1 gene

Indexed keywords

PROTEIN; UNCLASSIFIED DRUG; YEAST ARTIFICIAL PROTEIN;

ARTICLE; BASAL CELL NEVUS SYNDROME; BLOOD; CHROMOSOME ANALYSIS; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE LOCUS; GENE LOSS; GENE MUTATION; HEART MUSCLE FIBROMA; HEART TUMOR; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERPHASE; KARYOTYPE; MALE; METAPHASE; PRIORITY JOURNAL; PTCH1 GENE; TUMOR SUPPRESSOR GENE;

EID: 38749128639     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carpath.2007.08.001     Document Type: Article

References (19)

1. A.P. Burke M. Rosado-de-Christenson P.A. Templeton R. Virmani Cardiac fibroma: clinicopathologic correlates and surgical treatment J Thorac Cardiovasc Surg 108 1994 862 870
2. A.E. Becker Primary heart tumors in the pediatric age group: a review of salient pathologic features relevant for clinicians Pediatr Cardiol 21 2000 317 323
3. I.J. Reece D.A. Cooley O.H. Frazier G.L. Hallman P.L. Powers C.G. Montero Cardiac tumors: Clinical spectrum and prognosis of lesions other than classical benign myxoma in 20 patients J Thorac Cardiovasc Surg 88 3 1984 439 446
4. B. Davies G. Oppido C.P. Brizard Surgical management of symptomatic cardiac fibromas in children J Thorac Cardiovasc Surg 133 2007 254 255
5. R.J. Gorlin R.W. Goltz Multiple nevoid basal cell epithelioma, jaw cysts and bifid rib syndrome N Engl J Med 262 1960 908 912
6. P.A. Farndon R.G. Del Mastro D. Gareth R. Evans M.W. Kilpatrick Location of gene for Gorlin syndrome Lancet 33 1992 581 582
7. Y. Chen G. Struhl Dual roles for Patched in sequestering and transducing Hedgehog Cell 87 1996 553 563
8. H.L. Ferguson E.P. Hawkins L.D. Cooley Infant cardiac fibroma with clonal t(1;9)(q32;q22) and review of benign fibrous tissue cytogenetics Cancer Genet Cytogenet 87 1 1996 34 37
9. S. Viswanathan J.L. Gibbs P. Roberts Clonal translocation in a cardiac fibroma presenting with incessant ventricular tachycardia in childhood Cardiol Young 13 1 2003 101 102
10. W.D. Travis E. Brambilla H.K. Muller-Hermelink C.C. Harris World Health Organization Classification of Tumors. Pathology and genetics of tumors of the lung, pleura, thymus and heart 2004 IARC Press Lyon 268 270
11. P.A. Althof K. Ohmori M. Zhou Cytogenetic and molecular cytogenetic findings in 43 aneurysmal bone cysts: aberrations of 17p mapped to 17p13.2 by fluorescence in situ hybridization Mod Pathol 17 2004 518 525
12. ISCN L.G. Shaffer N. Tommerup An international system for human cytogenetic nomenclature 2005 Karger Basel 39 94
13. I.P. Blair D.J. Hulme J.L. Dawkins G.A. Nicholson A YAC-based transcript map of human chromosome 9q22.1-q22.3 encompassing the loci for hereditary sensory neuropathy type I and multiple self-healing squamous epithelioma Genomics 51 1998 277 281
14. J.A. Bridge V. Weibolt J. Liu Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study Genes Chromosom Cancer 27 2000 337 344
15. V.E. Kimonis A.M. Goldstein B. Pastakia Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome Am J Med Genet 69 1997 299 308
16. M. Beghetti R.M. Gow I. Haney J. Mawson W.G. Williams R.M. Freedom Pediatric primary benign cardiac tumors: a 15-year review Am Heart J 134 1997 1107 1114
17. R.J. Gorlin Nevoid basal cell carcinoma (Gorlin) syndrome Genet Med 6 6 2004 530 539
18. Firtenberg MS, Thomas JD. Benign Cardiac Tumors, E-medicine from WebMD [Online]. Available at: http://www.emedicine.com/med/topic2999.htm#section~miscellaneous and/or http://www.emedicine.com/med/topic299.htm. Accessed April 26, 2007.
19. M.R. Gailani M. Ståhle-Bäckdahl D.J. Lefell The role of the human homologue of drosophila patched in sporadic basal cell carcinomas Nat Genet 14 1 1996 78 81