Traumatic brain injury induces adipokine gene expression in rat brain

Neuroscience Letters

Volumn 432, Issue 1, 2008, Pages 73-78

  Brown, Russell ^a   Thompson, Hilaire J ^c   Imran, Syed A ^a,b   Ur, Ehud ^a,b   Wilkinson, Michael ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cortex; Fasting induced adipose factor (FIAF); Hypothalamus; Inflammation; Leptin; Lipopolysaccharide (LPS); Resistin

Indexed keywords

ADIPOCYTOKINE; LEPTIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN FIAF; RESISTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN METABOLISM; CACHEXIA; CONTROLLED STUDY; ENCEPHALITIS; ENERGY METABOLISM; GENE EXPRESSION; GENE INDUCTION; HIPPOCAMPUS; IMMUNOMODULATION; MALE; NEUROPROTECTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THALAMUS; TRAUMATIC BRAIN INJURY;

ADIPOKINES; ANIMALS; BRAIN; BRAIN INJURIES; CEREBRAL CORTEX; ENCEPHALITIS; ENERGY METABOLISM; GENE EXPRESSION; HYPOTHALAMUS; LEPTIN; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RESISTIN; RNA, MESSENGER; THALAMUS;

EID: 38749120585     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.12.008     Document Type: Article

References (29)

1. Ahima R.S., Bjorbaek C., Osei S., and Flier J.S. Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology 140 (1999) 2755-2762
2. Ahima R.S., Qi Y., and Singhal N.S. Adipokines that link obesity and diabetes to the hypothalamus. Prog. Brain Res. 153 (2006) 155-174
3. Belanger A.J., Lu H., Date T., Liu L.X., Vincent K.A., Akita G.Y., Cheng S.H., Gregory R.J., and Jiang C. Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J. Mol. Cell. Cardiol. 34 (2002) 765-774
4. Bond B.C., Virley D.J., Cairns N.J., Hunter A.J., Moore G.B., Moss S.J., Mudge A.W., Walsh F.S., Jazin E., and Preece P. The quantification of gene expression in an animal model of brain ischaemia using TaqMan real-time RT-PCR. Brain Res. Mol. Brain Res. 106 (2002) 101-116
5. Brown R., Morash B., Ur E., and Wilkinson M. RNAi-mediated silencing of leptin gene expression increases cell death in C6 glioblastoma cells. Brain Res. Mol. Brain Res. 139 (2005) 357-360
6. Carbonell W.S., and Grady M.S. Regional and temporal characterization of neuronal, glial, and axonal response after traumatic brain injury in the mouse. Acta Neuropathol. (Berl.) 98 (1999) 396-406
7. Dash P.K., Kobori N., and Moore A.N. A molecular description of brain trauma pathophysiology using microarray technology: an overview. Neurochem. Res. 29 (2004) 1275-1286
8. Dicou E., Attoub S., and Gressens P. Neuroprotective effects of leptin in vivo and in vitro. Neuroreport 12 (2001) 3947-3951
9. Emery D.L., Raghupathi R., Saatman K.E., Fischer I., Grady M.S., and McIntosh T.K. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. J. Comp. Neurol. 424 (2000) 521-531
10. Grosfeld A., Andre J., Hauguel-De Mouzon S., Berra E., Pouyssegur J., and Guerre-Millo M. Hypoxia-inducible factor 1 transactivates the human leptin gene promoter. J. Biol. Chem. 277 (2002) 42953-42957
11. Hayashi T., Noshita N., Sugawara T., and Chan P.H. Temporal profile of angiogenesis and expression of related genes in the brain after ischemia. J. Cereb. Blood Flow Metab. 23 (2003) 166-180
12. Koster A., Chao Y.B., Mosior M., Ford A., Gonzalez-DeWhitt P.A., Hale J.E., Li D., Qiu Y., Fraser C.C., Yang D.D., Heuer J.G., Jaskunas S.R., and Eacho P. Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology 146 (2005) 4943-4950
13. Le Jan S., Amy C., Cazes A., Monnot C., Lamande N., Favier J., Philippe J., Sibony M., Gasc J.M., Corvol P., and Germain S. Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. Am. J. Pathol. 162 (2003) 1521-1528
14. Lu S.C., Shieh W.Y., Chen C.Y., Hsu S.C., and Chen H.L. Lipopolysaccharide increases resistin gene expression in vivo and in vitro. FEBS Lett. 530 (2002) 158-162
15. Matzilevich D.A., Rall J.M., Moore A.N., Grill R.J., and Dash P.K. High-density microarray analysis of hippocampal gene expression following experimental brain injury. J. Neurosci. Res. 67 (2002) 646-663
16. McIntosh T.K., Vink R., Noble L., Yamakami I., Fernyak S., Soares H., and Faden A.L. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience 28 (1989) 233-244
17. Moinard C., Neveux N., Royo N., Genthon C., Marchand-Verrecchia C., Plotkine M., and Cynober L. Characterization of the alteration of nutritional state in brain injury induced by fluid percussion in rats. Intens. Care Med. 31 (2005) 281-288
18. Morales D.M., Marklund N., Lebold D., Thompson H.J., Pitkanen A., Maxwell W.L., Longhi L., Laurer H., Maegele M., Neugebauer E., Graham D.I., Stocchetti N., and McIntosh T.K. Experimental models of traumatic brain injury: do we really need to build a better mousetrap?. Neuroscience 136 (2005) 971-989
19. Nag S. The blood-brain barrier and cerebral angiogenesis: lessons from the cold-injury model. Trends Mol. Med. 8 (2002) 38-44
20. Paradis E., Clement S., Julien P., and Ven Murthy M.R. Lipoprotein lipase affects the survival and differentiation of neural cells exposed to very low density lipoprotein. J. Biol. Chem. 278 (2003) 9698-9705
21. Prins M.L., and Hovda D.A. Developing experimental models to address traumatic brain injury in children. J. Neurotraum. 20 (2003) 123-137
22. Royo N.C., Shimizu S., Schouten J.W., Stover J.F., and McIntosh T.K. Pharmacology of traumatic brain injury. Curr. Opin. Pharmacol. 3 (2003) 27-32
23. Russo V.C., Metaxas S., Kobayashi K., Harris M., and Werther G.A. Antiapoptotic effects of leptin in human neuroblastoma cells. Endocrinology 145 (2004) 4103-4112
24. Sihver S., Marklund N., Hillered L., Langstrom B., Watanabe Y., and Bergstrom M. Changes in mACh, NMDA and GABA(A) receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections. J. Neurochem. 78 (2001) 417-423
25. Thompson H.J., Tkacs N.C., Saatman K.E., Raghupathi R., and McIntosh T.K. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiol. Dis. 12 (2003) 163-173
26. Trayhurn P., and Wood I.S. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br. J. Nutr. 92 (2004) 347-355
27. Wiesner G., Brown R.E., Robertson G.S., Imran S.A., Ur E., and Wilkinson M. Increased expression of the adipokine genes resistin and fasting-induced adipose factor in hypoxic/ischaemic mouse brain. Neuroreport 17 (2006) 1195-1198
28. Wilkinson M., Brown R., Imran S.A., and Ur E. Adipokine gene expression in brain and pituitary gland. Neuroendocrinology 86 (2007) 191-209
29. F. Zhang, S. Wang, A.P. Signore, J. Chen, Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia, Program No. 759.15. 2006 Neuroscience Meeting Planner, Atlanta GA, Society for Neuroscience, 2006.