-
1
-
-
0021024932
-
Carnitine-metabolism and functions
-
Bremer J. Carnitine-metabolism and functions. Physiol. Rev. 63 (1983) 1420-1480
-
(1983)
Physiol. Rev.
, vol.63
, pp. 1420-1480
-
-
Bremer, J.1
-
3
-
-
0027166659
-
Carnitine metabolism and human carnitine deficiency
-
Ganphaichitr V., and Leelahagul P. Carnitine metabolism and human carnitine deficiency. Nutrition 9 (1993) 246-254
-
(1993)
Nutrition
, vol.9
, pp. 246-254
-
-
Ganphaichitr, V.1
Leelahagul, P.2
-
4
-
-
31544451294
-
Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM
-
Gonzalez-Alvarez I., Fernandez-Teruel C., Garrigues T.M., Casabo V.G., Ruiz-Garcia A., and Bermejo M. Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM. Xenobiotica 35 (2005) 1067-1088
-
(2005)
Xenobiotica
, vol.35
, pp. 1067-1088
-
-
Gonzalez-Alvarez, I.1
Fernandez-Teruel, C.2
Garrigues, T.M.3
Casabo, V.G.4
Ruiz-Garcia, A.5
Bermejo, M.6
-
5
-
-
11144281351
-
Expression, localization, and function of the carnitine transporter OCTN2 (slc22a5) in human placenta
-
Grube M., Schwabedissen H.M., Draber K., Prager D., Moritz K.U., Linnemann K., Fusch C., Jedlitschky G., and Kroemer H.K. Expression, localization, and function of the carnitine transporter OCTN2 (slc22a5) in human placenta. Drug Metab. Dispos. 33 (2005) 31-37
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 31-37
-
-
Grube, M.1
Schwabedissen, H.M.2
Draber, K.3
Prager, D.4
Moritz, K.U.5
Linnemann, K.6
Fusch, C.7
Jedlitschky, G.8
Kroemer, H.K.9
-
6
-
-
0028147853
-
The stimulative effect of diffusion potential on enoxacin uptake across rat intestinal brush-border membranes
-
Hirano T., Iseki K., Miyazaki S., Takada M., Kobayashi M., Sugawara M., and Miyazaki K. The stimulative effect of diffusion potential on enoxacin uptake across rat intestinal brush-border membranes. J. Pharm. Pharmacol. 46 (1994) 676-679
-
(1994)
J. Pharm. Pharmacol.
, vol.46
, pp. 676-679
-
-
Hirano, T.1
Iseki, K.2
Miyazaki, S.3
Takada, M.4
Kobayashi, M.5
Sugawara, M.6
Miyazaki, K.7
-
7
-
-
0028805557
-
The intestinal transport mechanism of fluoroquinolones: inhibitory effect of ciprofloxacin, an enoxacin derivative, on the membrane potential-dependent uptake of enoxacin
-
Hirano T., Iseki K., Sato I., Miyazaki S., Takada M., Kobayashi M., Sugawara M., and Miyazaki K. The intestinal transport mechanism of fluoroquinolones: inhibitory effect of ciprofloxacin, an enoxacin derivative, on the membrane potential-dependent uptake of enoxacin. Pharm. Res. 12 (1995) 1299-1303
-
(1995)
Pharm. Res.
, vol.12
, pp. 1299-1303
-
-
Hirano, T.1
Iseki, K.2
Sato, I.3
Miyazaki, S.4
Takada, M.5
Kobayashi, M.6
Sugawara, M.7
Miyazaki, K.8
-
8
-
-
33750524034
-
Mechanism of the inhibitory effect of zwitterionic drugs (levofloxacin and grepafloxacin) on carnitine transporter (OCTN2) in Caco-2 cells
-
Hirano T., Yasuda S., Osaka Y., Kobayashi M., Itagaki S., and Iseki K. Mechanism of the inhibitory effect of zwitterionic drugs (levofloxacin and grepafloxacin) on carnitine transporter (OCTN2) in Caco-2 cells. Biochim. Biophys. Acta 1758 (2006) 1743-1750
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1743-1750
-
-
Hirano, T.1
Yasuda, S.2
Osaka, Y.3
Kobayashi, M.4
Itagaki, S.5
Iseki, K.6
-
9
-
-
0024410225
-
Carnitine deficiency induced by pivampicillin and pivmecillinam therapy
-
Holme E., Greter J., Jacobson C.E., Lindstedt S., Nordin I., Kristiansson B., and Jodal U. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet 2 (1989) 469-473
-
(1989)
Lancet
, vol.2
, pp. 469-473
-
-
Holme, E.1
Greter, J.2
Jacobson, C.E.3
Lindstedt, S.4
Nordin, I.5
Kristiansson, B.6
Jodal, U.7
-
10
-
-
0025952029
-
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children
-
Hug G., McGraw C.A., Bates S.R., and Landrigan E.A. Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children. J. Pediatr. 119 (1991) 799-802
-
(1991)
J. Pediatr.
, vol.119
, pp. 799-802
-
-
Hug, G.1
McGraw, C.A.2
Bates, S.R.3
Landrigan, E.A.4
-
11
-
-
0025131270
-
Secondary carnitine deficiency in handicapped patients receiving valproic acid and/or elemental diet
-
Igarashi N., Sato T., and Kyouya S. Secondary carnitine deficiency in handicapped patients receiving valproic acid and/or elemental diet. Acta Paediatr. Jpn. 32 (1990) 139-145
-
(1990)
Acta Paediatr. Jpn.
, vol.32
, pp. 139-145
-
-
Igarashi, N.1
Sato, T.2
Kyouya, S.3
-
12
-
-
17644374513
-
Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2
-
Itoh T., Itagaki S., Sumi Y., Hirano T., Takemoto I., and Iseki K. Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2. Cancer Chemother. Pharmacol. 55 (2005) 420-424
-
(2005)
Cancer Chemother. Pharmacol.
, vol.55
, pp. 420-424
-
-
Itoh, T.1
Itagaki, S.2
Sumi, Y.3
Hirano, T.4
Takemoto, I.5
Iseki, K.6
-
14
-
-
3242676117
-
l-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2
-
Lahjouji K., Elimrani I., Lafond J., Leduc L., Qureshi I.A., and Mitchell G.A. l-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2. Am. J. Physiol. Cell Physiol. 287 (2004) C263-C269
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Lahjouji, K.1
Elimrani, I.2
Lafond, J.3
Leduc, L.4
Qureshi, I.A.5
Mitchell, G.A.6
-
15
-
-
0037005747
-
l-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles
-
Lahjouji K., Malo C., Mitchell G.A., and Qureshi I.A. l-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles. Biochim. Biophys. Acta 1558 (2002) 82-93
-
(2002)
Biochim. Biophys. Acta
, vol.1558
, pp. 82-93
-
-
Lahjouji, K.1
Malo, C.2
Mitchell, G.A.3
Qureshi, I.A.4
-
16
-
-
0032464623
-
Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC-PK1
-
Matsuo Y., Yano I., Ito T., Hashimoto Y., and Inui K. Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC-PK1. J. Pharmacol. Exp. Ther. 287 (1998) 672-678
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.287
, pp. 672-678
-
-
Matsuo, Y.1
Yano, I.2
Ito, T.3
Hashimoto, Y.4
Inui, K.5
-
17
-
-
0029929837
-
Reproductive and developmental toxicity studies of prulīoxacin (NM441)(2)-a teratogenicity study in rats by oral administration
-
Morinaga T., Fujii S., Furukawa S., Kikumori M., Yasuhira K., Shindo Y., Watanabe M., and Sumi N. Reproductive and developmental toxicity studies of prulīoxacin (NM441)(2)-a teratogenicity study in rats by oral administration. J. Toxicol. Sci. 21 (1996) 187-206
-
(1996)
J. Toxicol. Sci.
, vol.21
, pp. 187-206
-
-
Morinaga, T.1
Fujii, S.2
Furukawa, S.3
Kikumori, M.4
Yasuhira, K.5
Shindo, Y.6
Watanabe, M.7
Sumi, N.8
-
18
-
-
0035132434
-
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2
-
Ohashi R., Tamai I., Nezu J., Nikaido H., Hashimoto N., Oku A., Sai Y., Shimane M., and Tsuji A. Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. Mol. Pharmacol. 59 (2001) 358-366
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 358-366
-
-
Ohashi, R.1
Tamai, I.2
Nezu, J.3
Nikaido, H.4
Hashimoto, N.5
Oku, A.6
Sai, Y.7
Shimane, M.8
Tsuji, A.9
-
19
-
-
0347991796
-
A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin
-
Petitjeans F., Nadaud J., Perez J.P., Debien B., Olive F., Villevieille T., and Pats B. A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin. Eur. J. Clin. Pharmacol. 59 (2003) 779-780
-
(2003)
Eur. J. Clin. Pharmacol.
, vol.59
, pp. 779-780
-
-
Petitjeans, F.1
Nadaud, J.2
Perez, J.P.3
Debien, B.4
Olive, F.5
Villevieille, T.6
Pats, B.7
-
20
-
-
24644509835
-
Transfer of ciprofloxacin, ofloxacin and levofloxacin across the perfused human placenta in vitro
-
Polachek H., Holcberg G., Sapir G., Tsadkin-Tamir M., Polachek J., Katz M., and Ben-Zvi Z. Transfer of ciprofloxacin, ofloxacin and levofloxacin across the perfused human placenta in vitro. Eur. J. Obstet. Gynecol. Reprod. Biol. 122 (2005) 61-65
-
(2005)
Eur. J. Obstet. Gynecol. Reprod. Biol.
, vol.122
, pp. 61-65
-
-
Polachek, H.1
Holcberg, G.2
Sapir, G.3
Tsadkin-Tamir, M.4
Polachek, J.5
Katz, M.6
Ben-Zvi, Z.7
-
21
-
-
0028850504
-
Primary and secondary carnitine deficiency syndromes
-
Pons R., and De Vivo D.C. Primary and secondary carnitine deficiency syndromes. J. Child Neurol. 10 (1995) S8-S24
-
(1995)
J. Child Neurol.
, vol.10
-
-
Pons, R.1
De Vivo, D.C.2
-
22
-
-
11844273267
-
Novel organic cation transporter 2-mediated carnitine uptake in placental choriocarcinoma (BeWo) cells
-
Rytting E., and Audus K.L. Novel organic cation transporter 2-mediated carnitine uptake in placental choriocarcinoma (BeWo) cells. J. Pharmacol. Exp. Ther. 312 (2005) 192-198
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 192-198
-
-
Rytting, E.1
Audus, K.L.2
-
23
-
-
3342900005
-
Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice
-
Sasabe H., Kato Y., Suzuki T., Itose M., Miyamoto G., and Sugiyama Y. Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice. J. Pharmacol. Exp. Ther. 310 (2004) 648-655
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 648-655
-
-
Sasabe, H.1
Kato, Y.2
Suzuki, T.3
Itose, M.4
Miyamoto, G.5
Sugiyama, Y.6
-
24
-
-
0025363273
-
Primary carnitine deficiency
-
Scholte H.R., Pereira R.R., de Jonge P.C., Luyt-Houwen I.E.M., Hedwig M., Verduin M., and Ross J.D. Primary carnitine deficiency. J. Clin. Chem. Clin. Biochem. 28 (1990) 351-357
-
(1990)
J. Clin. Chem. Clin. Biochem.
, vol.28
, pp. 351-357
-
-
Scholte, H.R.1
Pereira, R.R.2
de Jonge, P.C.3
Luyt-Houwen, I.E.M.4
Hedwig, M.5
Verduin, M.6
Ross, J.D.7
-
25
-
-
0038177998
-
Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases
-
Shekhawat P., Bennett M.J., Sadovsky Y., Nelson D.M., Rakheja D., and Strauss A.W. Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases. Am. J. Physiol. Endocrinol. Metab. 284 (2003) E1098-E1105
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.284
-
-
Shekhawat, P.1
Bennett, M.J.2
Sadovsky, Y.3
Nelson, D.M.4
Rakheja, D.5
Strauss, A.W.6
-
26
-
-
0032493741
-
Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
-
Tamai I., Ohashi R., Nezu J., Yabuuchi H., Oku A., Shimane M., Sai Y., and Tsuji A. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J. Biol. Chem. 273 (1998) 20378-20382
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20378-20382
-
-
Tamai, I.1
Ohashi, R.2
Nezu, J.3
Yabuuchi, H.4
Oku, A.5
Shimane, M.6
Sai, Y.7
Tsuji, A.8
-
27
-
-
0031434178
-
Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
-
Tamai I., Yabuuchi H., Nezu J., Sai Y., Oku A., Shimane M., and Tsuji A. Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1. FEBS Lett. 419 (1997) 107-111
-
(1997)
FEBS Lett.
, vol.419
, pp. 107-111
-
-
Tamai, I.1
Yabuuchi, H.2
Nezu, J.3
Sai, Y.4
Oku, A.5
Shimane, M.6
Tsuji, A.7
-
28
-
-
0024246260
-
Primary carnitine deficiency due to failure of carnitine transport in kidney, muscle, and fibroblasts
-
Treem T.R., Stanley C.A., Finegold D.N., Hale D.E., and Coates P.M. Primary carnitine deficiency due to failure of carnitine transport in kidney, muscle, and fibroblasts. N. Engl. J. Med. 319 (1988) 1331-1336
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 1331-1336
-
-
Treem, T.R.1
Stanley, C.A.2
Finegold, D.N.3
Hale, D.E.4
Coates, P.M.5
-
29
-
-
0028030257
-
Toxicity of cephaloridine to carnitine transport and fatty acid metabolism in rabbit renal cortical mitochondria: structure-activity relationships
-
Tune B.M., and Hsu C.Y. Toxicity of cephaloridine to carnitine transport and fatty acid metabolism in rabbit renal cortical mitochondria: structure-activity relationships. J. Pharmacol. Exp. Ther. 270 (1994) 873-878
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 873-878
-
-
Tune, B.M.1
Hsu, C.Y.2
-
30
-
-
0032708146
-
Pharmacokinetics and pharmacodynamics of fluoroquinolones
-
Turnidge J. Pharmacokinetics and pharmacodynamics of fluoroquinolones. Drugs 58 (1999) 29-36
-
(1999)
Drugs
, vol.58
, pp. 29-36
-
-
Turnidge, J.1
-
31
-
-
0026832581
-
Reproductive toxicity study of new quinolones antibacterial agent levofloxacin in rats and rabbits
-
Watanabe T., Fujikawa K., Harada S., Ohura K., Sasaki T., and Takayama S. Reproductive toxicity study of new quinolones antibacterial agent levofloxacin in rats and rabbits. Arzneim. Forsch. 43 (1992) 374-377
-
(1992)
Arzneim. Forsch.
, vol.43
, pp. 374-377
-
-
Watanabe, T.1
Fujikawa, K.2
Harada, S.3
Ohura, K.4
Sasaki, T.5
Takayama, S.6
-
32
-
-
1542618510
-
Interaction between anticonvulsants and human placental carnitine transporter
-
Wu S.P., Shyu M.K., Liou H.H., Gau C.S., and Lin C.J. Interaction between anticonvulsants and human placental carnitine transporter. Epilepsia 45 (2004) 204-210
-
(2004)
Epilepsia
, vol.45
, pp. 204-210
-
-
Wu, S.P.1
Shyu, M.K.2
Liou, H.H.3
Gau, C.S.4
Lin, C.J.5
-
33
-
-
0033798408
-
Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2
-
Yamaguchi H., Yano I., Hashimoto Y., and Inui K. Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. J. Pharmacol. Exp. Ther. 295 (2000) 360-366
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 360-366
-
-
Yamaguchi, H.1
Yano, I.2
Hashimoto, Y.3
Inui, K.4
-
34
-
-
0035941155
-
Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2
-
Yamaguchi H., Yano I., Saito H., and Inui K. Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. Eur. J. Pharmacol. 431 (2001) 297-303
-
(2001)
Eur. J. Pharmacol.
, vol.431
, pp. 297-303
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.4
|