L-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles

Biochimica et Biophysica Acta - Biomembranes

Volumn 1558, Issue 1, 2002, Pages 82-93

  Lahjouji, Karim ^a   Malo, Christiane ^a   Mitchell, Grant A ^a   Qureshi, Ijaz A ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Carnitine; Intestinal membrane vesicle; Membrane transport; Mouse; OCTN2; Renal membrane vesicle

Indexed keywords

CARNITINE; CARRIER PROTEIN; MEPYRAMINE; POLYCLONAL ANTIBODY; TETRYLAMMONIUM; VALPROIC ACID; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; BINDING AFFINITY; CONTROLLED STUDY; INHIBITION KINETICS; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE EPITHELIUM; MEMBRANE VESICLE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE DEPENDENCE; TISSUE DISTRIBUTION; TRANSPORT KINETICS; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARNITINE; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; HYDROGEN-ION CONCENTRATION; INTESTINES; KIDNEY; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICROVILLI; ORGANIC CATION TRANSPORT PROTEINS; TEMPERATURE; TIME FACTORS;

EID: 0037005747     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(01)00433-3     Document Type: Article

References (40)

1. Carnitine transport
2. Carnitine transport in human intestinal biopsies: Demonstration of an active transport system
3. Uptake of L-carnitine by rat jejunal brush border microvillous membrane vesicles, evidence of passive diffusion
4. Uptake of L-carnitine by a human intestinal epithelial cell line, Caco-2
5. Biosynthesis and metabolism of carnitine
6. Primary systemic carnitine deficiency. II. Renal handling of carnitine
7. Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts
8. Sodium gradient-stimulated transport of L-carnitine into renal brush border membrane vesicles: Kinetics, specificity, and regulation by dietary carnitine
9. Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles
10. Primary and secondary carnitine deficiency
11. Sudden neonatal death in carnitine transporter deficiency
12. Cardiomyopathy associated with carnitine loss in kidney and small intestine
13. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
14. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
15. Infantile disease with microvesicular fatty infiltration of viscera spontaneously occurring in the C3H-H-2° strain of mouse with similarities to Reye's syndrome
16. Primary defect of juvenile visceral steatosis (jvs) mouse with systemic carnitine deficiency is probably in renal carnitine transport system
17. Loss of wild-type carrier-mediated L-carnitine transport activity in hepatocytes of juvenile visceral steatosis mice
18. A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse
19. α-Ketoglutarate transport in rat renal brush-border and basolateral membrane vesicles
20. Lysinuric protein intolerance mutation is expressed in the plasma membrane of cultured skin fibroblasts
21. Rabbit small intestinal brush border membrane preparation and lipid composition
22. +-D-glucose cotransport systems in the normal human fetal small intestine
23. Protein measurement with the folin phenol reagent
24. Alkaline phosphatase in adaptation to low dietary phosphate intake
25. Analytical isolation of plasma membranes of intestinal epithelial cells: Identification of Na, K-ATPase rich membranes and the distribution of enzyme activities
26. Transport of tetraethylammonium by rabbit renal brush-border and basolateral membrane vesicles
27. +-D-glucose cotransport in human intestinal brush-border membrane vesicles using a fast sampling, rapid filtration apparatus
28. Improved stability of rabbit and rat intestinal brush border membrane vesicles using phospholipase inhibitors
29. Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter
30. +-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
31. Novel membrane transporter OCTN1 mediates multispecific, bi-directional, and pH-dependent transport of organic cations
32. Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta
33. Molecular and functional characterization of organic cation/carnitine transporter family in mice
34. Molecular cloning and characterization of two novel transport proteins from rat kidney
35. Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine
36. +-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney
37. Reversal of valproic acid-associated impairment of carnitine uptake in cultured human skin fibroblasts
38. Valproic acid impairs carnitine uptake in cultured human skin fibroblasts. An in vitro model for the pathogenesis of valproic acid-associated carnitine deficiency
39. Carnitine metabolism and inborn errors
40. Characterization of L-carnitine transport into rat skeletal muscle plasma membrane vesicles