Effect of pretransplant preconditioning by whole body hyperthermia on islet graft survival

Cell Transplantation

Volumn 16, Issue 7, 2007, Pages 707-715

  Brandhorst, H ^a   Olbrich, M ^b   Neumann, A ^c   Jahr, H ^c   Brandhorst, Daniel ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b Division of Rheumatology   (Germany)

^c UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Apoptosis; Heat shock; Inflammation; Islet isolation; Rats; Whole body hyperthermia

Indexed keywords

DIETHYLENETRIAMINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GENE OVEREXPRESSION; GRAFT SURVIVAL; HEAT SHOCK; HYPERTHERMIA; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS RESECTION; PRIORITY JOURNAL; ANIMAL; CYTOLOGY; FEVER; GENETICS; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; NUDE MOUSE; PANCREAS ISLET TRANSPLANTATION; RAT; SWINE;

MUS MUSCULUS; RATTUS; SUIDAE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL MARKERS; FEVER; GRAFT SURVIVAL; HSP70 HEAT-SHOCK PROTEINS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SWINE; TRANSPLANTATION CONDITIONING;

EID: 38749108894     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000007783465163     Document Type: Article

References (31)

1. Abdelli, S.; Ansite, J.; Roduit, R.; Borsello, T.; Matsumoto, I.; Sawada, T.; Allaman-Pillet, N.; Henry, H.; Beckmann, J. S.; Hering, B. J.; Bonny, C. Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. Diabetes 53(11):2815-2823; 2004.
2. Beck, S. C.; Paidas, C. N.; Tan, H.; Yang, J.; De Maio, A. Depressed expression of the inducible form of HSP 70 (HSP 72) in brain and heart after in vivo heat shock. Am. J. Physiol. 269(3 Pt. 2):R608-613; 1995.
3. Bellmann, K.; Hui, L.; Radons, J.; Burkart, V.; Kolb, H. Low stress response enhances vulnerability of islet cells in diabetes-prone BB rats. Diabetes 46(2):232-236; 1997.
4. Bellmann, K.; Wenz, A.; Radons, J.; Burkart, V.; Kleemann, R.; Kolb, H. Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro. J. Clin. Invest. 95(6):2840-2845; 1995.
5. Bennet, W.; Groth, C. G.; Larsson, R.; Nilsson, B.; Korsgren, O. Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes. Ups. J. Med. Sci. 105(2):125-133; 2000.
6. Berney, T.; Molano, R. D.; Cattan, P.; Pileggi, A.; Vizzardelli, C.; Oliver, R.; Ricordi, C.; Inverardi, L. Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis. Transplantation 71(1):125-132; 2001.
7. Boreham, D. R.; Dolling, J. A.; Maves, S. R.; Miller, S.; Morrison, D. P.; Mitchel, R. E. Heat-induced thermal tolerance and radiation resistance to apoptosis in human lymphocytes. Biochem. Cell Biol. 75(4):393-397; 1997.
8. Bottino, R.; Balamurugan, A. N.; Tse, H.; Thirunavukkarasu, C.; Ge, X.; Profozich, J.; Milton, M.; Ziegenfuss, A.; Trucco, M.; Piganelli, J. D. Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes 53(10):2559-2568; 2004.
9. Bottino, R.; Fernandez, L. A.; Ricordi, C.; Lehmann, R.; Tsan, M. F.; Oliver, R.; Inverardi, L. Transplantation of allogeneic islets of Langerhans in the rat liver: Effects of macrophage depletion on graft survival and microenvironment activation. Diabetes 47(3):316-323; 1998.
10. Brandhorst, D.; Brandhorst, H.; Kumarasamy, V.; Maataoui, A.; Alt, A.; Brendel, M. D.; Bretzel, R. G. Hyperthermic preconditioning protects pig islet grafts from early inflammation but enhances rejection in immunocompetent mice. Cell Transplant. 12(8):859-865; 2003.
11. Brandhorst, D.; Hammes, H. P.; Brandhorst, H.; Zwolinski, A.; Nahidi, F.; Alt, A.; Bretzel, R. G. Pretransplant induction of HSP-70 in isolated adult pig islets decreases early islet xenograft survival. Cell Transplant. 9(3):423-430; 2000.
12. Brandhorst, H.; Brandhorst, D.; Brendel, M. D.; Hering, B. J.; Bretzel, R. G. Assessment of intracellular insulin content during all steps of human islet isolation procedure. Cell Transplant. 7(5):489-495; 1998.
13. Contreras, J. L.; Eckstein, C.; Smyth, C. A.; Sellers, M. T.; Vilatoba, M.; Bilbao, G.; Rahemtulla, F. G.; Young, C. J.; Thompson, J. A.; Chaudry, I. H.; Eckhoff, D. E. Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. Diabetes 52(12):2935-2942; 2003.
14. Jahr, H.; Hussmann, B.; Eckhardt, T.; Bretzel, R. G. Successful single donor islet allotransplantation in the streptozotocin diabetes rat model. Cell Transplant. 11(6):513-518; 2002.
15. Kawahara, D. J.; Kenney, J. S. Species differences in human and rat islet sensitivity to human cytokines. Monoclonal anti-interleukin-1 (IL-1) influences on direct and indirect IL-1-mediated islet effects. Cytokine 3(2):117-124; 1991.
16. Korbutt, G. S.; Elliott, J. F.; Ao, Z.; Smith, D. K.; Warnock, G. L.; Rajotte, R. V. Large scale isolation, growth, and function of porcine neonatal islet cells. J. Clin. Invest. 97(9):2119-2129; 1996.
17. Landry, J.; Bernier, D.; Chretien, P.; Nicole, L. M.; Tanguay, R. M.; Marceau, N. Synthesis and degradation of heat shock proteins during development and decay of thermotolerance. Cancer Res. 42(6):2457-2461; 1982.
18. Lenzen, S.; Drinkgern, J.; Tiedge, M. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic. Biol. Med. 20(3):463-466; 1996.
19. Matsumoto, K.; Honda, K.; Kobayashi, N. Protective effect of heat preconditioning of rat liver graft resulting in improved transplant survival. Transplantation 71(7):862-868; 2001.
20. Mizuno, N.; Yoshitomi, H.; Ishida, H.; Kuromi, H.; Kawaki, J.; Seino, Y.; Seino, S. Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion. Endocrinology 139(3):1429-1439; 1998.
21. Paraskevas, S.; Maysinger, D.; Wang, R.; Duguid, T. P.; Rosenberg, L. Cell loss in isolated human islets occurs by apoptosis. Pancreas 20(3):270-276; 2000.
22. Perdrizet, G. A.; Rewinski, M. J.; Schweizer, R. T.; Scharp, D. W. Heat shock and recovery protects pancreatic islets from warm ischemic injury. Transplant. Proc. 26(6):3477-3478; 1994.
23. Ricordi, C.; Gray, D. W. R.; Hering, B. J.; Kaufman, D. B.; Warnock, G. L.; Kneteman, N. M.; Lake, S. P.; London, N. J. M.; Socci, C.; Alejandro, R.; Zeng, Y. G.; Scharp, D. W.; Viviani, G.; Falqui, L.; Tzakis, A.; Bretzel, R. G.; Federlin, K.; Pozza, G.; James, R. F. L.; Rajotte, R. V.; DiCarlo, V.; Morris, P. J.; Sutherland, D. E. R.; Starzl, T. E.; Mintz, D. H.; Lacy, P. E. Islet isolation assessment in man and large animals. Acta Diabetol. Lat. 27:185-195; 1990.
24. Rosenberg, L.; Wang, R.; Paraskevas, S.; Maysinger, D. Structural and functional changes resulting from islet isolation lead to islet cell death. Surgery 126(2):393-398; 1999.
25. Ryan, E. A.; Lakey, J. R.; Paty, B. W.; Imes, S.; Korbutt, G. S.; Kneteman, N. M.; Bigam, D.; Rajotte, R. V.; Shapiro, A. M. Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes 51(7):2148-2157; 2002.
26. Sandberg, J. O.; Margulis, B.; Jansson, L.; Karlsten, R.; Korsgren, O. Transplantation of fetal porcine pancreas to diabetic or normoglycemic nude mice. Evidence of a rapid engraftment process demonstrated by blood flow and heat shock protein 70 measurements. Transplantation 59(12):1665-1669; 1995.
27. Shindo, Y.; Asanuma, Y.; Furuya, T.; Shibata, S.; Sato, T.; Itoh, H.; Koyama, K. Pretransplant heat loading on pancreatic graft reduces posttransplant ischemia-reperfusion injury. Transplant. Proc. 34(4):1329-1334; 2002.
28. Ulrichs, K.; Meyer, T.; Klock, G.; Chodnewska, I.; Czub, S.; Hamelmann, W.; Beutner, U.; Thiede, A. Monitoring of enzymatic digestions on porcine pancreatic tissue using a simple histological assay. Transplant. Proc. 30(2):355; 1998.
29. Welch, W. J. Mammalian stress response: Cell physiology, structure/function of stress proteins, and implications for medicine and disease. Physiol. Rev. 72(4):1063-1081; 1992.
30. Welch, W. J.; Suhan, J. P. Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment. J. Cell Biol. 101(4):1198-1211; 1985.
31. Welsh, M.; Eizirik, D. L.; Strandell, E. Heat-shock treatment of mouse pancreatic islets results in a partial loss of islet cells but no remaining functional impairment among the surviving beta cells. J. Mol. Endocrinol. 1(1):27-31; 1988.