Synthesis and anti-HIV activity of 2′-fluorine modified nucleoside phosphonates: Analogs of GS-9148

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 1116-1119

  Mackman, Richard L ^a   Lin, Kuei Ying ^a   Boojamra, Constantine G ^a   Hui, Hon ^a   Douglas, Janet ^a   Grant, Deborah ^a   Petrakovsky, Oleg ^a   Prasad, Vidya ^a   Ray, Adrian S ^a   Cihlar, Tomas ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

Antiviral; HIV; Phosphonate

Indexed keywords

2',3' DIDEHYDRO 2',3' DIDEOXY 2' FLUORO 5' O PHOSPHONOMETHYLADENOSINE; ADENOSINE DERIVATIVE; FLUORINE DERIVATIVE; GUANOSINE DERIVATIVE; NUCLEOSIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; TENOFOVIR;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN;

ANTI-HIV AGENTS; FLUORINE; GUANOSINE; HUMANS; MOLECULAR STRUCTURE; NUCLEOSIDES; PHOSPHONIC ACIDS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; ZIDOVUDINE;

EID: 38749105450     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.126     Document Type: Article

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