Antimalarial drugs and malignancy: No evidence of a protective effect in rheumatoid arthritis [2]

Annals of the Rheumatic Diseases

Volumn 67, Issue 2, 2008, Pages 277-278

  Bernatsky, Sasha ^a   Clarke, A ^a   Suissa, S ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; HYDROXYCHLOROQUINE; NONSTEROID ANTIINFLAMMATORY AGENT;

CANCER CELL; CANCER RISK; CONFIDENCE INTERVAL; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; IN VITRO STUDY; LETTER; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIMALARIALS; ANTINEOPLASTIC AGENTS; ARTHRITIS, RHEUMATOID; DISEASE SUSCEPTIBILITY; FEMALE; HUMANS; MALARIA; MALE; NEOPLASMS;

EID: 38749101024     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.075705     Document Type: Letter

References (6)

1. Fernandez Y, Ramakrishnan R, Rathinavelu A. Effect of systemic lupus erythematosus (SLE) treatment drugs on GI-101A breast tumor cell growth. Life Sci 2000;67:567-75.
2. Martirosyan AR, Rahim-Bata R, Freeman AB, Clarke CD, Howard RL, Strobl JS. Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model. Biochem Pharmacol 2004;68:1729-38.
3. Lagneaux L, Delforge A, Carlier S, Massy M, Bernier M, Bron D. Early induction of apoptosis in B-chronic lymphocytic leukaemia cells by hydroxychloroquine: activation of caspase-3 and no protection by survival factors. Br J Haematol 2001;112:344-52.
4. Ruiz-Irastorza G, Ugarte A, Egurbide MV, Garmendia M, Pijoan JI, Martinez-Berriotxoa A, et al. Antimalarials may influence the risk of malignancy in systemic lupus erythematosus. Ann Rheum Dis 2007;66:815-17.
5. King J, Costenbader K. Characteristics of patients with systemic lupus erythematosus (SLE) and non-Hodgkins lymphoma (NHL). Clin Rheumatol 2007; (Published online ahead of print).
6. Suissa S. Immortal time bias in observational studies of drug effects. Pharmacoepidemiol Drug Saf 2007;16:241-9.