The Effect of Sirolimus in the Development of Chronic Allograft Nephropathy

Transplantation Proceedings

Volumn 40, Issue 1, 2008, Pages 114-116

  Gurkan A ^a   Kacar S ^a   Erdogdu U ^a   Varilsuha C ^a   Kandemir, G ^b   Karaca, C ^a   Akman, F ^a  

^a SSK Tepecik Teaching Hospital   (Turkey)

^b Micro Private Pathology Center   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CREATININE; CYCLOSPORIN A; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; RAPAMYCIN; SUGAR; TRIACYLGLYCEROL;

ARTICLE; BLOOD PRESSURE MEASUREMENT; CHRONIC ALLOGRAFT NEPHROPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DISEASE COURSE; DRUG EFFECT; DRUG EFFICACY; FOLLOW UP; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY INFILTRATE; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA; TREATMENT OUTCOME;

ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOPSY; CHRONIC DISEASE; CREATININE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; SIROLIMUS; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 38749091678     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.11.005     Document Type: Article

References (20)

1. Wolfe R.A., Ashby V.B., Milford E.L., et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 341 (1999) 1725
2. Laupacis A., Keown P., Pus N., et al. A study of the quality life and cost-utility of renal transplantation. Kidney Int 50 (1996) 235
3. US Renal Data System: Available at: www.usrds.org
4. Ojo A.O., Hanson J.A., Wolfe R.A., et al. Long-term survival in renal transplant recipients with graft function. Kidney Int 57 (2000) 307
5. Chapman J.R. Longitudinal analysis of chronic allograft nephropathy; clinicopathologic correlations. Kidney Int 99 (2005) S108
6. Morales J.M., Andres A., Rengel M., et al. Influence of cyclosporin or tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. Nephrol Dial Transplant 16 (2001) 121
7. Saunders R.N., Metcalfe M.S., and Nicholson M.L. Rapamycin in transplantation: a review of the evidence. Kidney Int 70 (2001) 3
8. Knoll G., Muirhead N., Trpeski L., et al. Patient survival following renal transplant failure in Canada. Am J Transplant 5 (2005) 1719
9. Nankivell B.J., Borrows R.J., Fung C.L., et al. The natural history of chronic allograft nephropathy. N Eng J Med 349 (2003) 2326
10. de Mattos A., Olyaei A., and Bennett W. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. Am J Kidney Dis 35 (2000) 333
11. Joosten S., van Kooten C., and Paul L. Pathogenesis of chronic allograft rejection. Transplant Int 16 (2003) 137
12. Weir M.R., Blahut S., Drachernburg C., et al. Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. Am J Nephrol 24 (2004) 379
13. Vitko S., Tedesco H., Eris J., et al. Everolimus with optimized cyclosporine dosing in renal transplant recipients: 6-month safety and efficacy results of two randomized studies. Am J Transplant 4 (2004) 626
14. Mota A., Arias M., Taskinen E.I., et al. Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years. Am J Transplant 4 (2004) 1869
15. Isoniemi H., Krogerus L., von Willebrand E., et al. Histopathologic findings in well-functioning, long-term renal allografts. Kidney Int 41 (1992) 155
16. Ortiz F., Paavonen T., Törnroth T., et al. Predictors of renal allograft histologic damage progression. J Am Soc Nephrol 16 (2005) 817
17. Pribylova-Hribova P., Kotsch K., Lodererova A., et al. TGF-β1 mRNA upregulation influences chronic renal allograft dysfunction. Kidney Int 69 (2006) 1872
18. Nicholson M.L., Waller J.R., and Bicknell G.R. Renal transplant fibrosis correlates with intragraft expression of tissue inhibitor of metaloproteinase messenger RNA. Br J Surg 89 (2002) 933
19. Ishimura T., Ishida T., and Fujisawa M. Significance of early biopsy in pediatric kidney transplantation. Aktuel Urol 34 (2003) 234
20. Coupes B.M., Newstead C.G., Short C.D., et al. Transforming growth factor β1 in renal allograft recipients. Transplantation 57 (1994) 1727