Transcriptional regulation of the COX-2 expression by nitric oxide in colon cancer cell lines

Oncology Reports

Volumn 19, Issue 1, 2008, Pages 269-274

  Liu, Qiang ^a   Inoue, Hiroyasu ^b   Mahendran, Ratha ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NARA WOMEN'S UNIVERSITY   (Japan)

Author keywords

CRE and NF IL6 transcription factor binding sites; Cyclooxygenase 2; Nitric oxide

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; S NITROSOTHIOL;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; ENZYME REGULATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 38749088342     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.19.1.269     Document Type: Article

References (33)

1. Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S and DuBois RN: Up-regulation of the cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107: 1183-1188, 1994.
2. Rigas B, Goldman IS and Levine L: Altered eicosanoid levels in human colon cancer. J Lab Clin Med 122: 518-523, 1993.
3. Kutchera W, Jones DA, Matsunami N, et al: Prostaglandin H synthase-2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. Proc Natl Acad Sci USA 93: 4816-4820, 1996.
4. Shao J, Sheng H, Inoue H, Morrow JD and DuBois RN: Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem 275: 33951-33956, 2000.
5. Inoue H, Nanayama T, Hara S, Yokoyama C and Tanabe T: The cyclic-AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase-2 gene in differentiated U937 monocytic cells. FEBS Lett 350: 51-54, 1994.
6. Howe LR, Crawford HC, Subbaramaiah K, Hassell JA, Dannenberg AJ and Brown AM: PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. J Biol Chem 276: 20108-20115, 2001.
7. Duque J, Fresno M and Iniguez MA: Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2. J Biol Chem 280: 8686-8693, 2005.
8. Meade EA, McIntyre TM, Zimmerman GA and Prescott SM: Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem 274: 8328-8334, 1999.
9. Araki Y, Okamura S, Hussain SP, et al: Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways. Cancer Res 63: 728-734, 2003.
10. Bing RJ, Miyataka M, Rich KA, Hanson N, Wang X, Slosser HD and Shi SR: Nitric oxide, prostanoids, cyclooxygenase and angiogenesis in colon and breast cancer. Clin Cancer Res 7: 3385-3392, 2001.
11. Mei JM, Hord NG, Winterstein DF, Donald SP and Phang JM: Expression of prostaglandin endoperoxide H synthase-2 induced by nitric oxide in conditionally immortalized murine colonic epithelial cells. FASEB J 14:1188-1201, 2000.
12. Kim SF, Huri DA and Snyder SH: Inducible nitric oxide synthase binds, S-nitrosylates and activates cyclooxygenase-2. Science 310: 1966-1970, 2005.
13. Park SW, Sung MW, Heo DS, Inoue H, Shim SH and Kim KH: Nitric oxide up-regulates the cyclooxygenase-2 expression through the cyclic-AMP response element in its promoter in several cancer cell lines. Oncogene 24: 6689-6698, 2005.
14. Liu Y, Borchert GL and Phang JM: Polyoma enhancer activator 3, an ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells. J Biol Chem 279: 18694-18700, 2004.
15. Fan X, Roy E, Zhu L, Murphy TC, Kozlowski M, Nanes MS and Rubin J: Nitric oxide donors inhibit luciferase expression in a promoter-independent fashion. J Biol Chem 278: 10232-10238, 2003.
16. Moncada S, Palmer RM and Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43: 109-142, 1991.
17. Lamarque D and Whittle BJ: Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors. Eur J Pharmacol 277: 187-194, 1995.
18. Freeman B: Free radical chemistry of nitric oxide. Looking at the dark side. Chest 105: 79S-84S, 1994.
19. Borutaite V and Brown GC: Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion. Free Radic Biol Med 35: 1457-1468, 2003.
20. Liu Q, Chan ST and Mahendran R: Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines. Carcinogenesis 24: 637-642, 2003.
21. Zeng H, Spencer NY and Hogg N: Metabolism of S-nitro-soglutathione by endothelial cells. Am J Physiol Heart Circ Physiol 281: H432-H439, 2001.
22. Liu W, Reinmuth N, Stoeltzing O, et al: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. Cancer Res 63: 3632-3636, 2003.
23. Tamura M, Sebastian S, Yang S, et al: Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B. J Biol Chem 277: 26208-26216, 2002.
24. Inoue H and Tanabe T: Transcriptional role of the nuclear factor -kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem Biophys Res Commun 244: 143-148, 1998.
25. Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK and Lee SS: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: downregulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 480-481: 243-268, 2001.
26. Duque J, Diaz-Munoz MD, Fresno M and Iniguez MA: Upregulation of cyclooxygenase-2 by interleukin-1 beta in colon carcinoma cells. Cell Signal 18: 1262-1269, 2006.
27. Hansen WR, Marvin KW, Potter S and Mitchell MD: Tumor necrosis factor-alpha regulation of prostaglandin H synthase-2 transcription is not through nuclear factor-kappa B in amnion-derived AV-3 cells. Placenta 21: 789-798, 2000.
28. Gulati AP, Yang YM, Harter D, et al: Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappa B, but not c-Jun N-terminal kinase and activated protein-1. Mol Carcinog 45: 26-37, 2006.
29. Calmels S, Hainaut P and Ohshima H: Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein. Cancer Res 57: 3365-3369, 1997.
30. Benoit V, de Moraes E, Dar NA, et al: Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappa B. Oncogene 25: 5708-5718, 2006.
31. Chen JJ, Huang WC and Chen CC: Transcriptional regulation of cyclooxygenase-2 in response to proteasome inhibitors involves reactive oxygen species-mediated signaling pathway and recruitment of CCAAT/ enhancer-binding protein delta and CREB-binding protein. Mol Biol Cell 16: 5579-5591, 2005.
32. Inoue H, Yokoyama C, Hara S, Tone Y and Tanabe T: Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of the nuclear factor for interleukin-6 expression site and cyclic-AMP response element. J Biol Chem 270: 24965-24971, 1995.
33. Tamura M, Sebastian S, Yang S, Gurates B, Fang Z, Okamura K and Bulun SE: Induction of cyclooxygenase-2 in human endometrial stromal cells by malignant endometrial epithelial cells: evidence for the involvement of extracellularly-regulated kinases and CCAAT/enhancer-binding proteins. J Mol Endocrinol 31: 95-104, 2003.