Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst1 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 979-982

  Troxler, Thomas ^a   Enz, Albert ^a   Hoyer, Daniel ^a   Langenegger, Daniel ^a   Neumann, Peter ^a   Pfäffli, Paul ^a   Schoeffter, Philippe ^a   Hurth, Konstanze ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Ergolines; GPCR; Lysergic acid derivatives; Selective sst1 receptor antagonists; Somatostatin; Somatostatin sst1 receptor

Indexed keywords

ERGOLINE DERIVATIVE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 5;

ANALYTIC METHOD; ARTICLE; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG POTENCY; DRUG STRUCTURE; PHYSICAL CHEMISTRY;

ANIMALS; BRAIN; ERGOLINES; HUMANS; MOLECULAR STRUCTURE; RATS; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN;

RODENTIA;

EID: 38749084155     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.030     Document Type: Article

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