SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 14, 2007, Pages 3988-3991

  Hurth, Konstanze ^a   Enz, Albert ^a   Floersheim, Philipp ^a   Gentsch, Conrad ^a   Hoyer, Daniel ^a   Langenegger, Daniel ^a   Neumann, Peter ^a   Pfäffli, Paul ^a   Sorg, Dieter ^a   Swoboda, Robert ^a   Vassout, Annick ^a   Troxler, Thomas ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Octahydro g quinoline (obeline); Somatostatin sst1 receptor antagonist

Indexed keywords

LIGAND; OBELINE DERIVATIVE; QUINOLINE DERIVATIVE; RECEPTOR SUBTYPE; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

LUMINESCENT PROTEINS; PIPERAZINES; RECEPTORS, SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34250350337     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.078     Document Type: Article

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