Enantiospecific gas chromatographic-mass spectrometric analysis of urinary methylphenidate: Implications for phenotyping

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 140-149

  LeVasseur, Natalie L ^c   Zhu, Hao Jie ^a   Markowitz, John S ^a,b   DeVane, C Lindsay ^b   Patrick, Kennerly S ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c School of Business   (United States)

Author keywords

Enantiomers; Esterase; Methylphenidate; Pharmacogenetics; Urine

Indexed keywords

ESTERASE; METHYLPHENIDATE; PHARMACOGENETICS; POOR METABOLIZER (PM); URINE;

BODY FLUIDS; CONCENTRATION (PROCESS); ENANTIOMERS; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM;

DRUG PRODUCTS;

CARBOXYLESTERASE; CARBOXYLESTERASE 1; METHYLPHENIDATE; N TRIFLUOROACETYLPROLYLPIPERIDINIUM; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DRUG EXCRETION; DRUG STRUCTURE; DRUG URINE LEVEL; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; ION MONITORING; MASS SPECTROMETRY; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; VALIDATION PROCESS;

ADULT; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; METHYLPHENIDATE; PHENOTYPE; STEREOISOMERISM;

EID: 38649139865     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.030     Document Type: Article

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