Development and characterization of a live attenuated influenza B virus vaccine candidate

Vaccine

Volumn 26, Issue 7, 2008, Pages 874-881

  Seo, Sang Uk ^a   Byun, Young Ho ^a   Lee, Eun Young ^a   Jung, Eun Ju ^a   Jang, Yo Han ^a   Kim, Hyun Ah ^b   Ha, Suk Hoon ^c   Lee, Kwang Hee ^a   Seong, Baik Lin ^a  

^a Yonsei University   (South Korea)

^b CJ Corporation   (South Korea)

^c Green Cross Company   (South Korea)

Author keywords

Cold adapted vaccine; Influenza B virus; Mouse model

Indexed keywords

INFLUENZA VACCINE; LIVE VACCINE; MEMBRANE PROTEIN; VIRUS HEMAGGLUTININ; VIRUS SIALIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CHICK EMBRYO; COLD ACCLIMATIZATION; CONTROLLED STUDY; EMBRYO; GENETIC REASSORTMENT; INFLUENZA; INFLUENZA VIRUS B; LOW TEMPERATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; VIRUS ATTENUATION; VIRUS GENOME; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; WILD TYPE; ZYGOTE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIBODIES, VIRAL; CHICK EMBRYO; COLD; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLUENZA B VIRUS; INFLUENZA VACCINES; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; REASSORTANT VIRUSES; VACCINATION; VACCINES, ATTENUATED; VIRUS REPLICATION;

EID: 38649133169     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.12.022     Document Type: Article

References (31)

1. Lin C.H., Huang Y.C., Chiu C.H., Huang C.G., Tsao K.C., and Lin T.Y. Neurologic manifestations in children with influenza B virus infection. Pediatr Infect Dis J 25 11 (2006) 1081-1083
2. McCullers J.A., Facchini S., Chesney P.J., and Webster R.G. Influenza B virus encephalitis. Clin Infect Dis 28 4 (1999) 898-900
3. Studahl M. Influenza virus and CNS manifestations. J Clin Virol 28 3 (2003) 225-232
4. Brassard D.L., Leser G.P., and Lamb R.A. Influenza B virus NB glycoprotein is a component of the virion. Virology 220 2 (1996) 350-360
5. Horvath C.M., Williams M.A., and Lamb R.A. Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide. EMBO J 9 8 (1990) 2639-2647
6. Yuan W., and Krug R.M. Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. EMBO J 20 3 (2001) 362-371
7. Simonsen L., Fukuda K., Schonberger L.B., and Cox N.J. The impact of influenza epidemics on hospitalizations. J Infect Dis 181 3 (2000) 831-837
8. Wright P.F., and Webster R.G. Orthomyxoviruses. Field virology. 4th ed. (2001), Lippincott Williams & Wilkins, Philadelphia 1533-1579
9. Cox R.J., Brokstad K.A., and Ogra P. Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scand J Immunol 59 1 (2004) 1-15
10. Kendal A.P. Cold-adapted live attenuated influenza vaccines developed in Russia: can they contribute to meeting the needs for influenza control in other countries?. Eur J Epidemiol 13 5 (1997) 591-609
11. Wareing M.D., and Tannock G.A. Live attenuated vaccines against influenza; an historical review. Vaccine 19 25/26 (2001) 3320-3330
12. Buonagurio D.A., Bechert T.M., Yang C.F., Shutyak L., D'Arco G.A., Kazachkov Y., et al. Genetic stability of live, cold-adapted influenza virus components of the FluMist/CAIV-T vaccine throughout the manufacturing process. Vaccine 24 12 (2006) 2151-2160
13. Mendelman P.M., Cordova J., and Cho I. Safety, efficacy and effectiveness of the influenza virus vaccine, trivalent, types A and B, live, cold-adapted (CAIV-T) in healthy children and healthy adults. Vaccine 19 17-19 (2001) 2221-2226
14. Klimov A.I., Cox N.J., Yotov W.V., Rocha E., Alexandrova G.I., and Kendal A.P. Sequence changes in the live attenuated, cold-adapted variants of influenza A/Leningrad/134/57 (H2N2) virus. Virology 186 2 (1992) 795-797
15. Klimov A.I., Egorov A.Y., Gushchina M.I., Medvedeva T.E., Gamble W.C., Rudenko L.G., et al. Genetic stability of cold-adapted A/Leningrad/134/47/57 (H2N2) influenza virus: sequence analysis of live cold-adapted reassortant vaccine strains before and after replication in children. J Gen Virol 76 Pt 6 (1995) 1521-1525
16. Snyder M.H., Betts R.F., DeBorde D., Tierney E.L., Clements M.L., Herrington D., et al. Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines. J Virol 62 2 (1988) 488-495
17. Chen Z., Aspelund A., Kemble G., and Jin H. Genetic mapping of the cold-adapted phenotype of B/Ann Arbor/1/66, the master donor virus for live attenuated influenza vaccines (FluMist(R)). Virology 345 2 (2006) 416-423
18. DeBorde D.C., Donabedian A.M., Herlocher M.L., Naeve C.W., and Maassab H.F. Sequence comparison of wild-type and cold-adapted B/Ann Arbor/1/66 influenza virus genes. Virology 163 2 (1988) 429-443
19. Edwards K.M., King J.C., Steinhoff M.C., Thompson J., Clements M.L., Wright P.F., et al. Safety and immunogenicity of live attenuated cold-adapted influenza B/Ann Arbor/1/86 reassortant virus vaccine in infants and children. J Infect Dis 163 4 (1991) 740-745
20. Hoffmann E., Mahmood K., Chen Z., Yang C.F., Spaete J., Greenberg H.B., et al. Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66. J Virol 79 17 (2005) 11014-11021
21. Maassab H.F., and Bryant M.L. The development of live attenuated cold-adapted influenza virus vaccine for humans. Rev Med Virol 9 4 (1999) 237-244
22. Alexandrova G.I., Maassab H.F., Kendal A.P., Medvedeva T.E., Egorov A.Y., Klimov A.I., et al. Laboratory properties of cold-adapted influenza B live vaccine strains developed in the US and USSR, and their B/Ann Arbor/1/86 cold-adapted reassortant vaccine candidates. Vaccine 8 1 (1990) 61-64
23. Chen G.W., Shih S.R., Hsiao M.R., Chang S.C., Lin S.H., Sun C.F., et al. Multiple genotypes of influenza B viruses co-circulated in Taiwan in 2004-2005. J Clin Microbiol 45 5 (2007) 1515-1522
24. Pechirra P., Nunes B., Coelho A., Ribeiro C., Goncalves P., Pedro S., et al. Molecular characterization of the HA gene of influenza type B viruses. J Med Virol 77 4 (2005) 541-549
25. Lee K.-H., Seo S.-U., Song J.-M., Lee C.-M., Kim H.-A., and Seong B.L. Characterization of live influenza vaccine donor strain derived from cold-adaptation of X-31 virus. Vaccine 24 11 (2006) 1966-1974
26. Maassab H.F., and DeBorde D.C. Development and characterization of cold-adapted viruses for use as live virus vaccines. Vaccine 3 5 (1985) 355-369
27. Murphy B.R., and Coelingh K. Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines. Viral Immunol 15 2 (2002) 295-323
28. Hatta M., and Kawaoka Y. The NB protein of influenza B virus is not necessary for virus replication in vitro. J Virol 77 10 (2003) 6050-6054
29. Whitaker-Dowling P., Lucas W., and Youngner J.S. Cold-adapted vaccine strains of influenza A virus act as dominant negative mutants in mixed infections with wild-type influenza A virus. Virology 175 2 (1990) 358-364
30. Romanova J.R., Ermachenko T.A., Alexandrova G.I., and Tannock G.A. Interference between cold-adapted (ca) influenza A and B vaccine reassortants or between ca reassortants and wild-type strains in eggs and mice. Vaccine 12 1 (1994) 23-27
31. Hannoun C., Megas F., and Piercy J. Immunogenicity and protective efficacy of influenza vaccination. Virus Res 103 1/2 (2004) 133-138