Genetic stability of live, cold-adapted influenza virus components of the FluMist®/CAIV-T vaccine throughout the manufacturing process

Vaccine

Volumn 24, Issue 12, 2006, Pages 2151-2160

  Buonagurio, Deborah A ^a   Bechert, Thomas M ^a,c   Yang, Chin Fen ^b   Shutyak, Leonid ^a   D'Arco, Gail A ^a   Kazachkov, Yuriy ^a,d   Wang, Hai Ping ^a   Rojas, Eduardo A ^a   O'Neill, Robert E ^a   Spaete, Richard R ^b   Coelingh, Kathleen L ^b   Zamb, Timothy J ^a,e   Sidhu, Mohinder S ^a   Udem, Stephen A ^a  

^a WYETH RESEARCH   (United States)

^b MEDIMMUNE   (United States)

^c UK)   (United States)

^d SANOFI PASTEUR   (France)

^e INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

Author keywords

CAIV T; Cold adapted influenza virus vaccine; FluMist ; Genetic stability; LAIV

Indexed keywords

COLD ADAPTED INFLUENZA VIRUS VACCINE; HEMAGGLUTININ; INFLUENZA VACCINE; SIALIDASE; UNCLASSIFIED DRUG;

ARTICLE; COLD ACCLIMATIZATION; CONTROLLED STUDY; GENE SEQUENCE; GENETIC STABILITY; INFLUENZA; INFLUENZA VIRUS A; INFLUENZA VIRUS B; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TEMPERATURE SENSITIVITY; VACCINE PRODUCTION; VIRUS ATTENUATION; VIRUS MUTATION;

ADAPTATION, PHYSIOLOGICAL; ADMINISTRATION, INTRANASAL; AEROSOLS; COLD; INFLUENZA A VIRUS; INFLUENZA VACCINES; VACCINES, ATTENUATED; VIRUS CULTIVATION;

EID: 32844454631     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.11.007     Document Type: Article

References (23)

1. L. Simonsen The global impact of influenza on morbidity and mortality Vaccine 17 Suppl. 1 1999 S3 S10
2. T. Szucs The socio-economic burden of influenza J Antimicrob Chemother 44 Suppl. B 1999 11 15
3. R.A. Lamb, and R.M. Krug Orthomyxoviridae: the viruses and their replication D.M. Knipe P.M. Howley Fields virology 4th ed. 2001 Lippincott Williams & Wilkins 1487 1531
4. H.F. Maassab, and M.L. Bryant The development of live attenuated cold-adapted influenza virus vaccine for humans Rev Med Virol 9 4 1999 237 244
5. B.R. Murphy, and K. Coelingh Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines Viral Immunol 15 2 2002 295 323
6. N.J. Cox, F. Kitame, A.P. Kendal, H.F. Maassab, and C. Naeve Identification of sequence changes in the cold-adapted, live attenuated influenza vaccine strain, A/Ann Arbor/6/60 (H2N2) Virology 167 2 1988 554 567
7. D.C. DeBorde, A.M. Donabedian, M.L. Herlocher, C.W. Naeve, and H.F. Maassab Sequence comparison of wild-type and cold-adapted B/Ann Arbor/1/66 influenza virus genes Virology 163 2 1988 429 443
8. M.L. Herlocher, A.C. Clavo, and H.F. Maassab Sequence comparisons of A/AA/6/60 influenza viruses: mutations which may contribute to attenuation Virus Res 42 1-2 1996 11 25
9. E. Hoffmann, K. Mahmood, Z. Chen, C.F. Yang, J. Spaete, and H.B. Greenberg Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66 J Virol 79 17 2005 11014 11021
10. J.D. Parvin, A. Moscona, W.T. Pan, J.M. Leider, and P. Palese Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1 J Virol 59 2 1986 377 383
11. D.B. Smith, and S.C. Inglis The mutation rate and variability of eukaryotic viruses: an analytical review J Gen Virol 68 Part 11 1987 2729 2740
12. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1 1987 156 159
13. M.S. Sidhu, J.P. Menonna, S.D. Cook, P.C. Dowling, and S.A. Udem Canine distemper virus L gene: sequence and comparison with related viruses Virology 193 1 1993 50 65
14. H. Jin, B. Lu, H. Zhou, C. Ma, J. Zhao, and C.F. Yang Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60 Virology 306 1 2003 18 24
15. J.S. Robertson, M. Schubert, and R.A. Lazzarini Polyadenylation sites for influenza virus mRNA J Virol 38 1 1981 157 163
16. M. Yamashita, M. Krystal, W.M. Fitch, and P. Palese Influenza B virus evolution: co-circulating lineages and comparison of evolutionary pattern with those of influenza A and C viruses Virology 163 1 1988 112 122
17. D.C. Wiley, I.A. Wilson, and J.J. Skehel Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation Nature 289 5796 1981 373 378
18. A.J. Caton, G.G. Brownlee, J.W. Yewdell, and W. Gerhard The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype) Cell 31 2 Part 1 1982 417 427
19. M. Eigen, and C.K. Biebricher Sequence space and quasispecies distribution E. Domingo J.J. Holland P. Ahlquist RNA genetics 1988 CRC Press Inc. Boca Raton 211 245
20. M.E. Halloran, I.M. Longini Jr., M.J. Gaglani, P.A. Piedra, H. Chu, and G.B. Herschler Estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (CAIV-T) against influenza A (H1N1) and B using surveillance cultures Am J Epidemiol 158 4 2003 305 311
21. A.S. Gambaryan, V.P. Marinina, A.B. Tuzikov, N.V. Bovin, I.A. Rudneva, and B.V. Sinitsyn Effects of host-dependent glycosylation of hemagglutinin on receptor-binding properties on H1N1 human influenza A virus grown in MDCK cells and in embryonated eggs Virology 247 2 1998 170 177
22. G.C. Schild, J.S. Oxford, J.C. de Jong, and R.G. Webster Evidence for host-cell selection of influenza virus antigenic variants Nature 303 5919 1983 706 709
23. J.S. Robertson, C.W. Naeve, R.G. Webster, J.S. Bootman, R. Newman, and G.C. Schild Alterations in the hemagglutinin associated with adaptation of influenza B virus to growth in eggs Virology 143 1 1985 166 174