메뉴 건너뛰기




Volumn 47, Issue 1, 2008, Pages 160-168

Lack of renal improvement with nonselective endothelin antagonism with tezosentan in type 2 hepatorenal syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; CEFUROXIME; CITALOPRAM; CLONAZEPAM; CLOXACILLIN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; FLUCONAZOLE; GLICLAZIDE; INSULIN; LACTULOSE; LAMIVUDINE; LANSOPRAZOLE; MAGNESIUM; METRONIDAZOLE; MIDODRINE; NADOLOL; OCTREOTIDE; OLANZAPINE; OMEPRAZOLE; PREDNISONE; PROPRANOLOL; TEZOSENTAN; THYROXINE;

EID: 38649114358     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21940     Document Type: Article
Times cited : (44)

References (47)
  • 2
    • 34548120893 scopus 로고    scopus 로고
    • Hepatorenal syndrome: Update on pathogenesis and treatment. A Consensus Workshop of the International Ascites Club
    • Salerno F, Gerbes A, Gines P, Wong F, Arroyo V. Hepatorenal syndrome: update on pathogenesis and treatment. A Consensus Workshop of the International Ascites Club. Gut 2007;56:1310-1318.
    • (2007) Gut , vol.56 , pp. 1310-1318
    • Salerno, F.1    Gerbes, A.2    Gines, P.3    Wong, F.4    Arroyo, V.5
  • 3
    • 0036098337 scopus 로고    scopus 로고
    • Hepatorenal syndrome in cirrhosis: Pathogenesis and treatment
    • Arroyo V, Guevara M, Ginès P. Hepatorenal syndrome in cirrhosis: pathogenesis and treatment. Gastroenterology 2002;122:1658-1676.
    • (2002) Gastroenterology , vol.122 , pp. 1658-1676
    • Arroyo, V.1    Guevara, M.2    Ginès, P.3
  • 4
    • 0034087697 scopus 로고    scopus 로고
    • Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem
    • Arroyo V, Jimenez W. Complications of cirrhosis. II. Renal and circulatory dysfunction. Lights and shadows in an important clinical problem. J Hepatol 2000;32(Suppl 1):157-170.
    • (2000) J Hepatol , vol.32 , Issue.SUPPL. 1 , pp. 157-170
    • Arroyo, V.1    Jimenez, W.2
  • 5
    • 0023749667 scopus 로고
    • Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis
    • Schrier R, Arroyo V, Bernardi M, Epstein M, Henriksen JH, Rodes J. Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis. HEPATOLOGY 1988;8:1151-1157.
    • (1988) HEPATOLOGY , vol.8 , pp. 1151-1157
    • Schrier, R.1    Arroyo, V.2    Bernardi, M.3    Epstein, M.4    Henriksen, J.H.5    Rodes, J.6
  • 6
    • 0033804058 scopus 로고    scopus 로고
    • Plasma levels of endothelin-1 in patients with the hepatorenal syndrome after successful liver transplantation
    • Bachmann-Brandt S, Bittner I, Neuhaus P, Frei U, Schindler R. Plasma levels of endothelin-1 in patients with the hepatorenal syndrome after successful liver transplantation. Transpl Int 2000;13:357-362.
    • (2000) Transpl Int , vol.13 , pp. 357-362
    • Bachmann-Brandt, S.1    Bittner, I.2    Neuhaus, P.3    Frei, U.4    Schindler, R.5
  • 7
    • 12244268673 scopus 로고    scopus 로고
    • Systemic and regional changes in plasma endothelin following transient increase in portal pressure
    • Kapoor D, Redhead DN, Hayes PC, Webb DJ, Jalan R. Systemic and regional changes in plasma endothelin following transient increase in portal pressure. Liver Transpl 2003;9:32-39.
    • (2003) Liver Transpl , vol.9 , pp. 32-39
    • Kapoor, D.1    Redhead, D.N.2    Hayes, P.C.3    Webb, D.J.4    Jalan, R.5
  • 8
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M, Kurihara H, Kimura Y, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-415.
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, Y.3    Tomobe, Y.4    Kobayashi, M.5    Mitsui, Y.6
  • 9
    • 0036224493 scopus 로고    scopus 로고
    • Endothelin receptor antagonists: Structures, synthesis, selectivity and therapeutic applications
    • Boss C, Bolli M, Weller T. Endothelin receptor antagonists: structures, synthesis, selectivity and therapeutic applications. Curr Med Chem 2002; 9:349-383.
    • (2002) Curr Med Chem , vol.9 , pp. 349-383
    • Boss, C.1    Bolli, M.2    Weller, T.3
  • 10
    • 0026490970 scopus 로고
    • Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome
    • Moore K, Wendon J, Frazer M, Karani J, Williams R, Badr K. Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. N Engl J Med 1992;327:1774-1778.
    • (1992) N Engl J Med , vol.327 , pp. 1774-1778
    • Moore, K.1    Wendon, J.2    Frazer, M.3    Karani, J.4    Williams, R.5    Badr, K.6
  • 11
    • 0026742266 scopus 로고
    • Clinical significance of elevated plasma endothelin concentration in patients with cirrhosis
    • Uchihara M, Izumi N, Sato C, Marumo F. Clinical significance of elevated plasma endothelin concentration in patients with cirrhosis. HEPATOLOGY 1992;16:95-99.
    • (1992) HEPATOLOGY , vol.16 , pp. 95-99
    • Uchihara, M.1    Izumi, N.2    Sato, C.3    Marumo, F.4
  • 12
    • 0342468273 scopus 로고    scopus 로고
    • Plasma endothelin-1 and-3 in cirrhosis: Relationship with systemic hemodynamics, renal function, and neurohumoral systems
    • Bernardi M, Gülberg V, Colantoni A, Trevisani F, Gasbarrini A, Gerbes AL. Plasma endothelin-1 and-3 in cirrhosis: relationship with systemic hemodynamics, renal function, and neurohumoral systems. J Hepatol 1996;24:161-168.
    • (1996) J Hepatol , vol.24 , pp. 161-168
    • Bernardi, M.1    Gülberg, V.2    Colantoni, A.3    Trevisani, F.4    Gasbarrini, A.5    Gerbes, A.L.6
  • 13
    • 0028917843 scopus 로고
    • Endothelin-1 and -3 plasma concentrations in patients with cirrhosis of the liver - role of splanchnic and renal passage and liver function
    • Gerbes AL, Moller S, Gülberg V, Henriksen JH. Endothelin-1 and -3 plasma concentrations in patients with cirrhosis of the liver - role of splanchnic and renal passage and liver function. HEPATOLOGY 1995;21: 735-739.
    • (1995) HEPATOLOGY , vol.21 , pp. 735-739
    • Gerbes, A.L.1    Moller, S.2    Gülberg, V.3    Henriksen, J.H.4
  • 14
    • 0036137009 scopus 로고    scopus 로고
    • Endothelin is an important determinant of renal function in a rat model of acute liver and renal failure
    • Anand R, Harry D, Holt S, Milner P, Dashwood M, Goodier D, et al. Endothelin is an important determinant of renal function in a rat model of acute liver and renal failure. Gut 2002;50:111-117.
    • (2002) Gut , vol.50 , pp. 111-117
    • Anand, R.1    Harry, D.2    Holt, S.3    Milner, P.4    Dashwood, M.5    Goodier, D.6
  • 15
    • 0036788931 scopus 로고    scopus 로고
    • Role of endothelin-1 in a cirrhotic rat model with endotoxin induced acute renal failure
    • Ozdogan O, Goren M, Ratip S, Giral A, Moini H, Enc F, et al. Role of endothelin-1 in a cirrhotic rat model with endotoxin induced acute renal failure. Hepatol Res 2002;24:114.
    • (2002) Hepatol Res , vol.24 , pp. 114
    • Ozdogan, O.1    Goren, M.2    Ratip, S.3    Giral, A.4    Moini, H.5    Enc, F.6
  • 16
    • 0029786171 scopus 로고    scopus 로고
    • Amelioration of hepatorenal syndrome with selective endothelin-A antagonist
    • Soper CPR, Latif AB, Bending MR. Amelioration of hepatorenal syndrome with selective endothelin-A antagonist. Lancet 1996;347:1842-1843.
    • (1996) Lancet , vol.347 , pp. 1842-1843
    • Soper, C.P.R.1    Latif, A.B.2    Bending, M.R.3
  • 18
    • 38649123818 scopus 로고    scopus 로고
    • Clozel M, Clozel J-P, Hess P, Roux S, Sprecher U. Biochemical and hemodynamic effects of the endothelin antagonist tezosentan in dogs with aortic cross-clamping: Relationship to the dose. Allschwil, Switzerland: Actelion Pharmaceuticals Ltd Research; September 25, 2000. Research Report B-00.031.
    • Clozel M, Clozel J-P, Hess P, Roux S, Sprecher U. Biochemical and hemodynamic effects of the endothelin antagonist tezosentan in dogs with aortic cross-clamping: Relationship to the dose. Allschwil, Switzerland: Actelion Pharmaceuticals Ltd Research; September 25, 2000. Research Report B-00.031.
  • 19
    • 0034925011 scopus 로고    scopus 로고
    • Endothelin mediates the altered renal hemodynamics associated with experimental congestive heart failure
    • Qiu C, Ding SS, Hess P, Clozel JP, Clozel M. Endothelin mediates the altered renal hemodynamics associated with experimental congestive heart failure. J Cardiovasc Pharmacol 2001;38:317-324.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 317-324
    • Qiu, C.1    Ding, S.S.2    Hess, P.3    Clozel, J.P.4    Clozel, M.5
  • 21
    • 0035956718 scopus 로고    scopus 로고
    • The use of the endothelin receptor antagonist tezosentan before or after renal ischemia protects renal function
    • Wilhelm SM, Stowe NT, Robinson AV, Schulak JA. The use of the endothelin receptor antagonist tezosentan before or after renal ischemia protects renal function. Transplantation 2001;71:211-216.
    • (2001) Transplantation , vol.71 , pp. 211-216
    • Wilhelm, S.M.1    Stowe, N.T.2    Robinson, A.V.3    Schulak, J.A.4
  • 22
    • 9344219968 scopus 로고    scopus 로고
    • Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats
    • Urbanowicz W, Sogni P, Moreau R, Tazi KA, Barriere E, Poirel O, et al. Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats. Gut 2004;53:1844-1849.
    • (2004) Gut , vol.53 , pp. 1844-1849
    • Urbanowicz, W.1    Sogni, P.2    Moreau, R.3    Tazi, K.A.4    Barriere, E.5    Poirel, O.6
  • 23
    • 0038461068 scopus 로고    scopus 로고
    • Moore KP, Wong F, Gines P, Ochs A, Bernardi M, Salerno F, et al. The management of ascites - report on the consensus conference of the International Ascites Club. HEPATOLOGY 2003;38:258-266.
    • Moore KP, Wong F, Gines P, Ochs A, Bernardi M, Salerno F, et al. The management of ascites - report on the consensus conference of the International Ascites Club. HEPATOLOGY 2003;38:258-266.
  • 24
    • 0028568928 scopus 로고
    • Evaluation of a short protocol for the determination of para-aminohippurate and inulin clearances
    • Minetti EE, Cozzi MG, Biella E, Napoli F, Guidi E. Evaluation of a short protocol for the determination of para-aminohippurate and inulin clearances. J Nephrol 1994;7:342-346.
    • (1994) J Nephrol , vol.7 , pp. 342-346
    • Minetti, E.E.1    Cozzi, M.G.2    Biella, E.3    Napoli, F.4    Guidi, E.5
  • 25
    • 0015530123 scopus 로고
    • Measurement of renal function without urine collection. A critical evaluation of the constant-infusion technic for determination of inulin and para-aminohippurate
    • Cole BR, Giangiacomo J, Ingelfinger JR, Robson AM. Measurement of renal function without urine collection. A critical evaluation of the constant-infusion technic for determination of inulin and para-aminohippurate. N Engl J Med 1972;287:1109-1114.
    • (1972) N Engl J Med , vol.287 , pp. 1109-1114
    • Cole, B.R.1    Giangiacomo, J.2    Ingelfinger, J.R.3    Robson, A.M.4
  • 26
    • 0026707373 scopus 로고
    • Fully enzymatic inulin determination in small volume samples
    • Kuehnle HF, von Dahl K, Schmidt FH. Fully enzymatic inulin determination in small volume samples. Nephron 1992;62:104-107.
    • (1992) Nephron , vol.62 , pp. 104-107
    • Kuehnle, H.F.1    von Dahl, K.2    Schmidt, F.H.3
  • 28
    • 0032895684 scopus 로고    scopus 로고
    • Measurement of plasma renin activity with use of HPLC-electrospray-tandem mass spectrometry
    • Fredline VF, Kovacs EM, Taylor PJ, Johnson AG. Measurement of plasma renin activity with use of HPLC-electrospray-tandem mass spectrometry. Clin Chem 1999;45:659-664.
    • (1999) Clin Chem , vol.45 , pp. 659-664
    • Fredline, V.F.1    Kovacs, E.M.2    Taylor, P.J.3    Johnson, A.G.4
  • 29
    • 0038645596 scopus 로고    scopus 로고
    • Determination of tezosentan, a parenteral endothelin receptor antagonist, in human plasma by liquid chromatography-tandem mass spectrometry
    • van Giersbergen PL, Wipfli P, Dingemanse J. Determination of tezosentan, a parenteral endothelin receptor antagonist, in human plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;792:369-373.
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.792 , pp. 369-373
    • van Giersbergen, P.L.1    Wipfli, P.2    Dingemanse, J.3
  • 33
    • 0017614941 scopus 로고
    • Renal blood flow in cirrhosis: Relation to systemic and portal haemodynamics and liver function
    • Ring-Larsen H. Renal blood flow in cirrhosis: relation to systemic and portal haemodynamics and liver function. Scand J Clin Lab Invest 1977; 37:635-642.
    • (1977) Scand J Clin Lab Invest , vol.37 , pp. 635-642
    • Ring-Larsen, H.1
  • 34
    • 8344252792 scopus 로고    scopus 로고
    • Effects of endothelin-1 and endothelin-1-receptor blockade on renal function in humans
    • Vuurmans JL, Boer P, Koomans HA. Effects of endothelin-1 and endothelin-1-receptor blockade on renal function in humans. Nephrol Dial Transplant 2004;19:2742-2746.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2742-2746
    • Vuurmans, J.L.1    Boer, P.2    Koomans, H.A.3
  • 35
    • 0037868058 scopus 로고    scopus 로고
    • Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure
    • Torre-Amione G, Young JB, Colucci WS, Lewis BS, Pratt C, Cotter G, et al. Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. J Am Coll Cardiol 2003;42:140-147.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 140-147
    • Torre-Amione, G.1    Young, J.B.2    Colucci, W.S.3    Lewis, B.S.4    Pratt, C.5    Cotter, G.6
  • 36
    • 0027371573 scopus 로고
    • Effect of different endothelin receptor antagonists and of the novel non-peptide antagonist Ro 46-2005 on endothelin levels in rat plasma
    • Löffler BM, Breu V, Clozel M. Effect of different endothelin receptor antagonists and of the novel non-peptide antagonist Ro 46-2005 on endothelin levels in rat plasma. FEBS Lett 1993;333:108-110.
    • (1993) FEBS Lett , vol.333 , pp. 108-110
    • Löffler, B.M.1    Breu, V.2    Clozel, M.3
  • 37
    • 0003326222 scopus 로고    scopus 로고
    • A double-blind, parallel-group, multi-center, placebo-controlled study to investigate the efficacy and safety of tezosentan in reducing symptoms in patients with acute decompensated heart failure [Abstract]
    • Teerlink JR, Massie BM, Cleland JGF, et al. A double-blind, parallel-group, multi-center, placebo-controlled study to investigate the efficacy and safety of tezosentan in reducing symptoms in patients with acute decompensated heart failure [Abstract]. Circulation 2001;104:II-526.
    • (2001) Circulation , vol.104 , Issue.II-526
    • Teerlink, J.R.1    Massie, B.M.2    Cleland, J.G.F.3
  • 39
    • 0038414660 scopus 로고    scopus 로고
    • Tezosentan in patients with acute heart failure and acute coronary syndromes: Results of the Randomized Intravenous TeZosentan Study (RITZ-4)
    • O'Connor CM, Gattis WA, Adams KF Jr, Hasselblad V, Chandler B, Frey A, et al. Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4). J Am Coll Cardiol 2003;41:1452-1457.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1452-1457
    • O'Connor, C.M.1    Gattis, W.A.2    Adams Jr, K.F.3    Hasselblad, V.4    Chandler, B.5    Frey, A.6
  • 40
    • 0037438919 scopus 로고    scopus 로고
    • RITZ-5: Randomized intravenous TeZosentan (an endothelin-A/B antagonist) for the treatment of pulmonary edema: a prospective, multicenter, double blind, placebo-controlled study
    • Kaluski E, Kobrin I, Zimlichman R, Marmor A, Krakov O, Milo O, et al. RITZ-5: randomized intravenous TeZosentan (an endothelin-A/B antagonist) for the treatment of pulmonary edema: a prospective, multicenter, double blind, placebo-controlled study. J Am Coll Cardiol 2003;41:204-210.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 204-210
    • Kaluski, E.1    Kobrin, I.2    Zimlichman, R.3    Marmor, A.4    Krakov, O.5    Milo, O.6
  • 41
    • 0036223958 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects
    • Dingemanse J, Clozel M, van Giersbergen PL. Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects. Br J Clin Pharmacol 2002;53:355-362.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 355-362
    • Dingemanse, J.1    Clozel, M.2    van Giersbergen, P.L.3
  • 42
    • 0029116310 scopus 로고
    • Endothelins
    • Levin ER. Endothelins. N Engl J Med 1995;333:356-363.
    • (1995) N Engl J Med , vol.333 , pp. 356-363
    • Levin, E.R.1
  • 43
    • 4043174201 scopus 로고    scopus 로고
    • The hemodynamic and neurohormonal effects of low doses of tezosentan (an endothelin A/B receptor antagonist) in patients with acute heart failure
    • Cotter G, Kaluski E, Stangl K, Pacher R, Richter C, Milo-Cotter O, et al. The hemodynamic and neurohormonal effects of low doses of tezosentan (an endothelin A/B receptor antagonist) in patients with acute heart failure. Eur J Heart Fail 2004;6:601-609.
    • (2004) Eur J Heart Fail , vol.6 , pp. 601-609
    • Cotter, G.1    Kaluski, E.2    Stangl, K.3    Pacher, R.4    Richter, C.5    Milo-Cotter, O.6
  • 44
    • 2442557223 scopus 로고    scopus 로고
    • Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock
    • Konrad D, Oldner A, Rossi P, Wanecek M, Rudehill A, Weitzberg E. Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock. Crit Care Med 2004;32:1192-1199.
    • (2004) Crit Care Med , vol.32 , pp. 1192-1199
    • Konrad, D.1    Oldner, A.2    Rossi, P.3    Wanecek, M.4    Rudehill, A.5    Weitzberg, E.6
  • 45
    • 0037369631 scopus 로고    scopus 로고
    • Enhanced vasodilatation to endothelin antagonism in patients with compensated cirrhosis and the role of nitric oxide
    • Helmy A, Newby DE, Jalan R, Hayes PC, Webb DJ. Enhanced vasodilatation to endothelin antagonism in patients with compensated cirrhosis and the role of nitric oxide. Gut 2003;52:410-415.
    • (2003) Gut , vol.52 , pp. 410-415
    • Helmy, A.1    Newby, D.E.2    Jalan, R.3    Hayes, P.C.4    Webb, D.J.5
  • 46
    • 0141534409 scopus 로고    scopus 로고
    • Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation
    • Vaughan RB, Angus PW, Chin-Dusting JPF. Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation. Gut 2003;52:1505-1510.
    • (2003) Gut , vol.52 , pp. 1505-1510
    • Vaughan, R.B.1    Angus, P.W.2    Chin-Dusting, J.P.F.3
  • 47
    • 33746803789 scopus 로고    scopus 로고
    • Role of endothelin and endothelin receptor antagonists in renal disease
    • Neuhofer W, Pittrow D. Role of endothelin and endothelin receptor antagonists in renal disease. Eur J Clin Invest 2006;36(Suppl 3):78-88.
    • (2006) Eur J Clin Invest , vol.36 , Issue.SUPPL. 3 , pp. 78-88
    • Neuhofer, W.1    Pittrow, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.