Screening and detection of portal vein tumor thrombi-associated serum low molecular weight protein biomarkers in human hepatocellular carcinoma

Journal of Cancer Research and Clinical Oncology

Volumn 134, Issue 3, 2008, Pages 299-305

  Qiu, Ji Gang ^a   Fan, Jia ^a   Liu, Yin Kun ^a   Zhou, Jian ^a   Dai, Zhi ^a   Huang, Cheng ^a   Tang, Zhao You ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

2 DE; HCC portal vein tumor thrombi; Hepatocellular carcinoma; PVTT proteomics two dimensional gel electrophoresis

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN C3; BIOLOGICAL MARKER; DNA TOPOISOMERASE (ATP HYDROLYSING); PREALBUMIN;

ADULT; ARTICLE; CANCER DIAGNOSIS; CANCER SCREENING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIVER CELL CARCINOMA; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; VASCULAR TUMOR;

AMINO ACID SEQUENCE; BLOOD PROTEINS; CARCINOMA, HEPATOCELLULAR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEOPLASM CIRCULATING CELLS; PORTAL VEIN; THROMBOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 38649109493     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-007-0236-7     Document Type: Article

References (21)

1. Ahmed N, Barker G, Oliva KT et al (2004) Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer. Br J Cancer 91(1):129-140
2. Curry S (2002) Beyond expansion: structural studies on the transport roles of human serum albumin. Vox Sang 45(Suppl 1):315-319
3. Dingmans AC, van Ark-Otte J, Span S et al (2001) Topoisomerase α alpha and other drug resistance markers in advanced non-small cell lung cancer. Lung Cancer 32:117-128
4. Fan J, Tang ZY, Wu ZQ et al (2005) The effects of portal vein microscopic and macroscopic tumor thrombi on post-operation patients with hepatocellular carcinoma. Zhonghua Wai Ke Za Zhi 43(7):433-435 (Chinese)
5. Feng JT, Liu YK, Song HY et al (2005) Heat-shock protein 27: a potential biomarker for hepatocellular carcinoma identified by serum proteome analysis. Proteomics 5:4581-4588
6. Gorg A, Obermaier C, Boguth G et al (2000) The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 12(6):1037-1053
7. Hachem H, Favre G, Raynal G et al (1986) Serum apolipoproteins A-I, A-II and B in hepatic metastases. Comparison with other liver diseases: hepatomas and cirrhosis. J Clin Chem Clin Biochem 24(3):161-166
8. He QY, Lau GK, Zhou Y et al (2003) Serum biomarkers of hepatitis B virus infected liver inflammation: a proteomic study. Proteomics 5(5):666-674
9. Jokin FI, Enrique S, Laura S et al (2005) Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis. Proteomics 5:4964-4972
10. Laemmmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
11. Lewis GF, Rader DJ (2005) New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res 96(12):1221-1232
12. Meliconi R, Parracino O, Facchini A et al (1988) Acute phase proteins in chronic and malignant liver diseases. Liver 4(2):65-74
13. Noriko O, Yoshihito I, Miyako N et al (2006) Fucosylated haptoglobin is a novel marker for pancreatic cancer: a detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation. Int J Cancer 118:2803-2808
14. Pieper R, Gaflin CL, Makusky AJ et al (2003) The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins. Proteomics 3:1345-1364
15. Schagger H, von Jagow G (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166(2):368-379
16. Shi JH, Zhao YT, Wang JL et al (2001) Study on analyzing methos of low molercular peptides with SDS polyacrylamide gel electrophoresis. Prog Biotechnol 21(1):38-41 (Chinese)
17. Strom MS, Nunn DN, Lory S (1993) A single bifunctional enzyme, PilD, catalyzes cleavage and N-methylation of proteins belonging to the type IV pilin family. Proc Natl Acad 90:2404-2408
18. Sturgeon C (2002) Practice Guidelines for tumor marker use in the clinic. Clin Chem 48(8):1151-1159
19. Tang ZY (2005) Hepatocellular carcinoma surgery-review of the past and prospects for the 21st century. J Surg Oncol 91(2):95-96
20. Turner GA (1995) Haptoglobin. A potential reporter molecule for glycosylation changes in disease. Adv Exp Med Biol 376:231-238
21. Watanuki A, Ohwada S, Fukusato T (2002) Prognostic significance of DNA topoisomerase II alpha expression in human hepatocellular carcinoma. Anticancer Res 22(2B):1113-1119