Human prion diseases: From antibody screening to a standardized fast immunodiagnosis using automation

Modern Pathology

Volumn 21, Issue 2, 2008, Pages 140-149

  Privat, Nicolas ^a,b,c   Laffont Proust, Isabelle ^a,b   Faucheux, Baptiste A ^a,b,c   Sazdovitch, Véronique ^a,b   Frobert, Yveline ^d   Laplanche, Jean Louis ^e   Grassi, Jacques ^d   Hauw, Jean Jacques ^b,c   Haïk, Stéphane ^a,b,c  

^a INSERM   (France)

^b InVS   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d Service de Pharmacologie et Immunoanalyse   (France)

^e HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Creutzfeldt Jakob disease; Diagnosis; Prion

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 12F10; PRION PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY SCREENING; ANTIGEN RETRIEVAL; ARTICLE; AUTOMATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; SYRIAN HAMSTER;

ALZHEIMER DISEASE; ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN; CREUTZFELDT-JAKOB SYNDROME; CRICETINAE; GERSTMANN-STRAUSSLER-SCHEINKER DISEASE; HUMANS; IMMUNOENZYME TECHNIQUES; MASS SCREENING; MESOCRICETUS; PREDICTIVE VALUE OF TESTS; PRION DISEASES; PRIONS; PRPSC PROTEINS; SHEEP;

EID: 38649093344     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800994     Document Type: Article

References (29)

1. Ironside JW. Prion diseases in man. J Pathol 1998; 186:227-234.
2. Kretzschmar HA, Ironside JW, Dearmond SJ, et al. Diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Arch Neurol 1996;53:913-920.
3. Kitamoto T, Ogomori K, Tateishi J, et al. Formic acid pre-treatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest 1987;57:230-236.
4. DeArmond SJ, Mobley WC, Demott DL, et al. Changes in the localization of brain prion proteins during scrapie infection. Neurology 1987;37:1271-1280.
5. Guiroy D, Yanagihara R, Gajdusek D. Localization of amyloidogenic proteins and sulfated glycosaminoglycans in nontransmissible and transmissible cerebral amyloidoses. Acta Neuropathol 1991;82:87-92.
6. Doi-Yi R, Kitamoto T, Tateishi J. Immunoreactivity of cerebral amyloidosis is enhanced by protein denaturation treatments. Acta Neuropathol 1991;82:260-265.
7. Kitamoto T, Shin RW, Dohura K, et al. Abnormal isoform of prion proteins accumulates in the synaptic structures of the central nervous system in patients with Creutzfeldt-Jakob disease. Am J Pathol 1992;140:1285-1294.
8. Hashimoto K, Mannen T, Nukina N. Immunohistochemical study of kuru plaques using antibodies against synthetic prion protein peptides. Acta Neuropathol 1992;83:613-617.
9. Haritani M, Spencer YI, Wells GA. Hydrated autoclave pre-treatment enhancement of prion protein immunoreactivity in formalin-fixed bovine spongiform encephalopathy-affected brain. Acta Neuropathol (Berl) 1994;87:86-90.
10. Hayward P, Bell J, Ironside J. Prion protein immunocytochemistry: reliable protocols for the investigation of Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol 1994;20:375-383.
11. Macdonald ST, Sutherland K, Ironside JW. A quantitative and qualitative analysis of prion protein immunohistochemical staining in Creutzfeldt-Jakob disease using four anti prion protein antibodies. Neurodegeneration 1996;5:87-94.
12. Kascsak RJ, Rubenstein R, Merz PA, et al. Mouse polyclonal and monoclonal antibody to SAF (PrP) protein. J Virol 1987;61:3688-3693.
13. Bell JE, Gentleman SM, Ironside JW, et al. Prion protein immunocytochemistry - UK five centre consensus report. Neuropathol Appl Neurobiol 1997;23:26-35.
14. Privat N, Sazdovitch V, Seilhean D, et al. PrP immunohistochemistry: different protocols, including a procedure for long formalin fixation, and a proposed schematic classification for deposits in sporadic Creutzfeldt-Jakob disease. Microsc Res Tech 2000;50:26-31.
15. Feraudet C, Morel N, Simon S, et al. Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J Biol Chem 2005;280:11247-11258.
16. Morel N, Simon S, Frobert Y, et al. Selective and efficient immunoprecipitation of the disease-associated form of the prion protein can be mediated by nonspecific interactions between monoclonal antibodies and scrapie-associated fibrils. J Biol Chem 2004;279:30143-30149.
17. Reik LM, Maines SL, Ryan DE, et al. A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. J Immunol Methods 1987;100:123-130.
18. Budka H, Aguzzi A, Brown P, et al. Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Brain Pathol 1995;5:459-466.
19. Parchi P, Castellani R, Capellari S, et al. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease. Ann Neurol 1996;39:767-778.
20. Schulz-Schaeffer WJ, Giese A, Windl O, et al. Polymorphism at codon 129 of the prion protein gene determines cerebellar pathology in Creutzfeldt-Jakob disease. Clin Neuropathol 1996;15:353-357.
21. Hauw JJ, Sazdovitch V, Laplanche JL, et al. Neuropathologic variants of sporadic Creutzfeldt-Jakob disease and codon 129 of PrP gene. Neurology 2000;54:1641-1646.
22. Hilton DA, Fathers E, Edwards P, et al. Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 1998;352:703-704.
23. Hilton DA, Ghani AC, Conyers L, et al. Prevalence of lymphoreticular prion protein accumulation in UK tissue samples. J Pathol 2004;203:733-739.
24. Hainfellner J, Wanschitz J, Jellinger K, et al. Coexistence of Alzheimer-type neuropathology in Creutzfeldt-Jakob disease. Acta Neuropathol 1998;96:116-122.
25. Kovacs GG, Head MW, Hegyi I, et al. Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes. Brain Pathol 2002;12:1-11.
26. Montagna P, Gambetti P, Cortelli P, et al. Familial and sporadic fatal insomnia. Lancet Neurol 2003;2:167-176.
27. Safar JG, Geschwind MD, Deering C, et al. Diagnosis of human prion disease. Proc Natl Acad Sci USA 2005;102:3501-3506.
28. Castilla J, Saa P, Soto C. Detection of prions in blood. Nat Med 2005;11:982-985.
29. Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001;411:810-813.