Type I hair cell degeneration in the utricular macula of the waltzing guinea pig

Hearing Research

Volumn 236, Issue 1-2, 2008, Pages 33-41

  Severinsen, Stig Å ^a   Raarup, Merete K ^a   Ulfendahl, Mats ^b,c   Wogensen, Lise ^d   Nyengaard, Jens R ^a   Kirkegaard, Mette ^b,c  

^a Institute of Clinical Medicine   (Denmark)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

Inner ear; Stereology; Utricular macula; Waltzing guinea pig

Indexed keywords

ANIMAL CELL; ARTICLE; CELL COUNT; CELL DEGENERATION; CELL POPULATION; CELL TYPE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; GUINEA PIG; HAIR CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL COUNT; GUINEA PIGS; HAIR CELLS, VESTIBULAR; HEARING LOSS; MEMBRANE GLYCOPROTEINS; MICROFILAMENT PROTEINS; MICROSCOPY, CONFOCAL; MUSCULOSKELETAL EQUILIBRIUM; SENSATION DISORDERS; TUBULIN;

EID: 38649084426     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2007.11.009     Document Type: Article

References (38)

1. Beyer L.A., Odeh H., Probst F.J., Lambert E.H., Dolan D.F., Camper S.A., Kohrman D., and Raphael Y. Hair cells in the Pirouette and Shaker-2 mutants. J. Neurocytol. 29 (2000) 227-239
2. Canlon B., Marklund K., and Borg E. Measures of auditory brain-stem responses, distortion product otoacoustic emissions, hair cell loss, and forward masked tuning curves in the waltzing guinea pig. J. Acoust. Soc. Am. 94 (1993) 3232-3243
3. Canlon B., and Dulon D. Dissociation between the calcium-induced and voltage-driven motility in cochlear outer hair cells from the waltzing guinea pig. J. Cell Sci. 104 (1993) 1137-1143
4. Daudet N., and Lebart M.C. Transient expression of the t-isoform of plastins/fimbrin in the stereocilia of developing auditory hair cells. Cell Motil. Cytoskeleton 53 (2002) 326-336
5. Desai S.S., Zeh C., and Lysakowski A. Comparative morphology of rodent vestibular periphery. I. Saccular and utricular maculae. J. Neurophysiol. 93 1 (2005) 251-266
6. Dorph-Petersen K.A., Nyengaard J.R., and Gundersen H.J. Tissue shrinkage and unbiased stereological estimation of particle number and size. J. Microsc. 204 3 (2001) 232-246
7. Ernstson S. Acta Otolaryngol. 69 (1970) 358-362
8. Ernstson S. Vestibular physiology in a strain of the waltzing guinea pig. Acta Otolaryngol. 72 (1971) 303-309
9. Ernstson S., Lundquist P.G., Wedenberg E., and Wersäll J. Morphologic changes in vestibular hair cells in a strain of the waltzing guinea pig. Acta Otolaryngol. 67 (1969) 521-534
10. Ernstson S., and Ulfendahl M. The German waltzing guinea pig: a new strain with a new pattern of inner ear degeneration. Assoc. Res. Otolaryngol. Abs. (1998) 229
11. Flock A., Cheung H., and Wersall J. Pathological actin in vestibular hair cells of the waltzing guinea pig. Adv. Otorhinolaryngol. 25 (1979) 12-16
12. Gundersen H.J. Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J. Microsc. 143 1 (1986) 3-45
13. Gundersen H.J., Jensen E.B., Kieu K., and Nielsen J. The efficiency of systematic sampling in stereology-reconsidered. J. Microsc. 193 (1999) 199-211
14. Ibsen L., and Risty T. A new character in guinea pigs, waltzing. Anat. Rec. 44 (1929) 294
15. Jin Z., Mannström P., Skjönsberg A., Järlebark L., and Ulfendahl M. Auditory function and cochlear morphology in the German waltzing guinea pig. Hearing Res. 219 1-2 (2006) 74-84
16. Kanzaki S., Beyer L.A., Canlon B., Meixner W.M., and Raphael Y. The cytocaud: a hair cell pathology in the waltzing guinea pig. Audiol. Neurootol. 7 5 (2002) 289-297
17. Kirkegaard M., and Nyengaard J.R. Stereological study of postnatal development in the mouse utricular macula. J. Comp. Neurol. 492 2 (2005) 132-144
18. Kirkegaard M., Severinsen S.A., Wogensen L., and Nyengaard J.R. Systemic Kanamycin treatment has no effect on cell numbers in the mouse utricular macula. Image Anal. Stereol. 24 (2005) 69-76
19. Lindeman H.H. Regional differences in structure of the vestibular sensory regions. J. Laryngol. Otol. 83 1 (1969) 1-17
20. Lindeman H.H. Studies on the morphology of the sensory regions of the vestibular apparatus. Adv. Anat. Embryol. Cell Biol. 42 (1969) 1-113
21. Marcus D.C., Rokugo M., Ge X.-X., and Thalmann R. Response of cochlear potentials to presumed alterations of ionic conductance: Endolymphatic perfusion of barium, valinomycin and nystatin. Hear. Res. 12 (1983) 17-30
22. Mburu P., Mustapha M., Varela A., Weil D., El Amraoui A., Holme R.H., Rump A., Hardisty R.E., Blanchard S., Coimbra R.S., Perfettini I., Parkinson N., Mallon A.M., Glenister P., Rogers M.J., Paige A.J., Moir L., Clay J., Rosenthal A., Liu X.Z., Blanco G., Steel K.P., Petit C., and Brown S.D. Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31. Nat. Genet. 34 (2003) 421-428
23. Mustapha, M., Beyer, L.A., Izumikawa, M., Swiderski, D.L., Dolan, D.F., Raphael, Y., Camper, S.A., 2007. Whirler mutant hair cells have less severe pathology than Shaker 2 or double mutants. J. Assoc. Res. Otolaryngol. doi:10.1007/s10162-007-0083-x.
24. Nordemar H. Postnatal development of the vestibular sensory epithelium in the mouse. Acta Otolaryngol. 96 5-6 (1983) 447-456
25. Nyengaard J.R. Stereologic methods and their application in kidney research. J. Am. Soc. Nephrol. 10 (1999) 1100-1123
26. Rüsch A., Lysakowski A., and Eatock R.A. Postnatal development of type I and type II hair cells in the mouse utricle: acquisition of voltage-gated conductances and differentiated morphology. J. Neurosci. 18 (1998) 7487-7501
27. Sánchez-Fernández J.M., and Rivera-Pomar J.M. A study of the development of utricular and saccular maculae in man and rat. Am. J. Otol. 5 1 (1983) 44-55
28. Skjönsberg A., Herrlin P., Duan M., Johnson A.-C., and Ulfendahl M. A guinea pig strain with recessive heredity of deafness, producing normal-hearing heterozygotes with resistance to noise trauma. Audiol. Neurotol. 10 (2005) 323-330
29. Sobin A., and Flock A. Sensory hairs and filament rods in vestibular hair cells of the waltzing guinea pig. Organization and identification of actin. Acta Otolaryngol. 91 3-4 (1981) 247-254
30. Sobin A., Anniko M., and Flock A. Rods of actin filaments in type I hair cells of the Shaker-2 mouse. Arch. Otorhinolaryngol. 236 (1982) 1-6
31. Sobin A., and Anniko M. Embryonic development of the specific vestibular hair cell pathology in a strain of the waltzing guinea pig. Acta Otolaryngol. 96 5-6 (1983) 397-405
32. Sobin A., and Flock A. Immunohistochemical identification and localization of actin and fimbrin in vestibular hair cells in the normal guinea pig and in a strain of the waltzing guinea pig. Acta Otolaryngol. 96 5-6 (1983) 407-412
33. Sobin A., and Wersäll J. A morphological study on vestibular sensory epithelia in a strain of the waltzing guinea pig. Acta Otolaryngol. Suppl. 396 (1983) 1-32
34. Sobin A., and Anniko M. Otoconial pathology in a strain of the waltzing guinea pig. Am. J. Otol. 7 6 (1986) 449-453
35. Wang A., Liang Y., Fridell R.A., Probst F.J., Wilcox E.R., Touchman J.W., Morton C.C., Morell R.J., Noben-Trauth K., Camper S.A., and Friedman T.B. Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3. Science 280 (1998) 1447-1451
36. Werner C.F. Die differenzierung der maculae im labyrinth, insbesondere bei säugetieren. Z. Anat. Entwickl.-Gesch. 99 (1933) 696-709
37. West M.J., Slomianka L., and Gundersen H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231 (1991) 482-497
38. Wit H.P., and Nijdam H.F. Relationship of gross cochlear potentials to hair cell pathology in the waltzing guinea pig. Hear. Res. 15 (1984) 159-171