Propofol infusion syndrome: A case of increasing morbidity with traumatic brain injury

American Journal of Critical Care

Volumn 16, Issue 1, 2007, Pages 82-85

  Sabsovich, Ilya ^a   Rehman, Zia ^a   Yunen, Jose ^a   Coritsidis, George ^a  

^a ELMHURST HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTRAVENOUS ANESTHETIC AGENT; PROPOFOL;

ACIDOSIS; ACUTE KIDNEY FAILURE; ADOLESCENT; ARTICLE; BRAIN INJURY; CASE REPORT; CHEMICALLY INDUCED DISORDER; FATALITY; HUMAN; HYPERLIPIDEMIA; MALE; RHABDOMYOLYSIS; SYNDROME; TACHYCARDIA;

ACIDOSIS; ADOLESCENT; ANESTHETICS, INTRAVENOUS; BRAIN INJURIES; FATAL OUTCOME; HUMANS; HYPERLIPIDEMIAS; KIDNEY FAILURE, ACUTE; MALE; PROPOFOL; RHABDOMYOLYSIS; SYNDROME; TACHYCARDIA;

EID: 38549177389     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2007.16.1.82     Document Type: Article

References (25)

1. Parke TJ, Stevens JE, Rice AS, et al. Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. BMJ. 1992;305:613-616.
2. Vasile B, Rasulo F, Candiani A, Latronico N. The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med. 2003;29:1417-1425.
3. Marinella MA. Lactic acidosis associated with propofol [letter]. Chest. 1996;109:292.
4. Perrier ND, Baerga-Varela Y, Murray MJ. Death related to propofol use in an adult patient. Crit Care Med. 2000;28:3071-3074.
5. Freidman JA, Manno E, Fulgham JR. Propofol. J Neurosurg. 2002; 96:1161-1162.
6. Cray SH, Robinson BH, Cox PN. Lactic acidosis and bradyarrhythmia in a child sedated with propofol. Crit Care Med. 1998;26:2087-2092.
7. Hanna JP, Ramundo ML. Rhabdomyolysis and hypoxia associated with prolonged propofol infusion in children. Neurology. 1998;50:301-303.
8. Stelow EB, Johari VP, Smith SA, Crosson JT, Apple FS. Propofol-associated rhabdomyolysis with cardiac involvement in adults: chemical and anatomic findings. Clin Chem. 2000;46:577-581.
9. Cremer OL, Moons KG, Bouman EA, Kruijswijk JE, de Smet AM, Kalkman CJ. Long term propofol infusion and cardiac failure in adult headinjured patients. Lancet. 2001;357:117-118.
10. Bray RJ. Propofol infusion syndrome in children. Paediatr Anaesth. 1998;8:491-499.
11. Eriksen J, Povey HM. A case of suspected non-neurosurgical adult fatal propofol infusion syndrome. Acta Anaesthesiol Scand. 2006;50:117-119.
12. Oertel M, Kelly DF, Lee JH, et al. Efficacy of hyperventilation blood pressure elevation and metabolic suppression therapy in controlling intracranial pressure after head injury. J Neurosurg. 2002;97:1045-1053.
13. Matta B, Menon D. Severe head injury in the United Kingdom and Ireland: a survey of practice and implications for management. Crit Care Med. 1996;24:1743-1748.
14. Diprivan (propofol) product monograph. Mississauga, Canada: Zeneca Pharma Inc.
15. Bennett SN, McNeil MM, Bland LA, et al. Postoperative infections traced to contamination of an intravenous anesthetic, propofol. N Engl J Med. 1995;333:147-154.
16. Grounds RM, Lalor JM, Lumley J, Royston D, Morgan M. Propofol infusion for sedation in the intensive care unit: preliminary report. BMJ. 1987;294:397-400.
17. Aitkenhead AR, Pepperman ML, Willats SM, et al. Comparison of propofol and midazolam for sedation in critically ill patients. Lancet. 1989;2(8665):704-709.
18. McKeage K, Perry CM. Propofol: a review of its use in intensive care sedation of adults. CNS Drugs. 2003;17:235-272.
19. Leisure GS, O'Flaherty J, Green L, Jones DR. Propofol and postoperative pancreatitis. Anesthesiology. 1996;84:224-227.
20. Nathwani RA, Pais S, Reynolds TB, Kaplowitz N. Serum alanine aminotransferase in skeletal muscle diseases. Hepatology. 2005;41:380-382.
21. Branca D, Roberti MS, Vincenti E, Scutari G. Uncoupling effect of the general anesthetic 2,6-diisopropylphenol in isolated rat liver mitochondria. Arch Biochem Biophys. 1991;290:517-521.
22. Schenkman KA, Yan SY. Propofol impairment of mitochondrial respiration in isolated perfused guinea pig hearts determined by reflectance spectrometry. Crit Care Med. 2000;28:172-177.
23. Myburgh JA, Upton RA, Grant C, Martinez A. Epinephrine, norepinephrine and dopamine infusions decrease propofol concentrations during continuous propofol infusion in an ovine model. Intensive Care Med. 2001;27:276-282.
24. Zhou W, Fontenot HJ, Wang SN, Kennedy RH. Propofol-induced alterations in myocardial beta-adrenoceptor binding and responsiveness. Anesth Analg. 1999;89:604-608.
25. Haase R, Sauer H, Eichler G. Lactic acidosis following short-term propofol infusion may be an early warning of propofol infusion syndrome. J Neurosurg Anesthesiol. 2005;17:122-123.