Formulation and development of floating capsules of celecoxib: In vitro and in vivo evaluation

AAPS PharmSciTech

Volumn 8, Issue 4, 2007, Pages

  Ali, Javed ^a   Arora, Shweta ^a   Ahuja, Alka ^a   Babbar, Anil K ^b   Sharma, Rakesh K ^b   Khar, Roop K ^a  

^a HAMDARD UNIVERSITY   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Celecoxib; Gamma scintigraphy; Gastroretentive systems; Single unit floating capsules

Indexed keywords

CELECOXIB; POLYMER; STANNOUS CHLORIDE; TECHNETIUM 99M; ACRYLIC ACID RESIN; EUDRAGIT RS; MACROGOL DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; SULFONAMIDE; TECHNETIUM; TIN DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG CAPSULE; DRUG FORMULATION; DRUG LABELING; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; GAMMA SCINTIGRAPHY; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LEACHING; MALE; NONHUMAN; PH MEASUREMENT; PROCESS OPTIMIZATION; RADIOACTIVITY; TRANSPORT KINETICS; ANIMAL; CHEMICAL MODEL; CHEMISTRY; DELAYED RELEASE FORMULATION; GASTROINTESTINAL TRANSIT; KINETICS; METABOLISM; METHODOLOGY; MICROCAPSULE; ORAL DRUG ADMINISTRATION; PH; PHARMACEUTICS; RABBIT; SCINTISCANNING; SOLUBILITY; STOMACH;

ACRYLIC RESINS; ADMINISTRATION, ORAL; ANIMALS; CAPSULES; CHEMISTRY, PHARMACEUTICAL; CYCLOOXYGENASE INHIBITORS; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; GASTROINTESTINAL TRANSIT; HYDROGEN-ION CONCENTRATION; KINETICS; MALE; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; POLYMERS; PYRAZOLES; RABBITS; RADIOPHARMACEUTICALS; SOLUBILITY; STOMACH; SULFONAMIDES; TECHNETIUM; TECHNOLOGY, PHARMACEUTICAL; TIN COMPOUNDS;

EID: 38549168492     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0804119     Document Type: Article

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