Statistical optimization of gastric floating system for oral controlled delivery of calcium

AAPS PharmSciTech

Volumn 2, Issue 1, 2001, Pages

  Li, Shoufeng ^a,e   Lin, Senshang ^a,d   Chien, Yie W ^a,c   Daggy, Bruce P ^b   Mirchandani, Haresh L ^b  

^a RUTGERS UNIVERSITY   (United States)

^b SmithKline Beecham Consumer Healthcare   (United States)

^c ST JOHN'S UNIVERSITY   (United States)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Calcium; Gastric floating system; Oral controlled delivery; Response surface methodology (RSM); Statistical optimization

Indexed keywords

CALCIUM CARBONATE; CITRIC ACID; HYDROXYPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; CALCIUM; PHARMACEUTICAL VEHICLES AND ADDITIVES;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; IN VITRO STUDY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; REGRESSION ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ANALYSIS OF VARIANCE; BIOAVAILABILITY; DELAYED RELEASE FORMULATION; DRUG FORMULATION; METABOLISM; METHODOLOGY; ORAL DRUG ADMINISTRATION; REPRODUCIBILITY; STATISTICS;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; BIOLOGICAL AVAILABILITY; CALCIUM; CALCIUM CARBONATE; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; PHARMACEUTIC AIDS; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS;

EID: 23144438961     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt020101     Document Type: Article

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