Oxygen consumption of keloids and hypertrophic scars

Annals of Plastic Surgery

Volumn 60, Issue 2, 2008, Pages 194-197

  Ichioka, Shigeru ^a   Ando, Taichi ^a   Shibata, Masahiro ^b   Sekiya, Naomi ^a   Nakatsuka, Takashi ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Clark electrode; Hypertrophic scar; Keloid; Oxygen consumption; Wound healing

Indexed keywords

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYPERTROPHIC SCAR; KELOID; MALE; MEASUREMENT; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN ELECTRODE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VALIDITY; WOUND HEALING;

ANIMALS; CICATRIX, HYPERTROPHIC; HUMANS; KELOID; MALE; MICE; MICE, INBRED STRAINS; OXYGEN CONSUMPTION; WOUND HEALING;

EID: 38549168379     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e318053ec1d     Document Type: Article

References (12)

1. Sloan DF, Brown RD, Wells CH, et al. Tissue gases in human hypertrophic burn scars. Plast Reconstr Surg. 1978;61:431-436.
2. Cohen IK, Keiser HR. Collagen synthesis in keloid and hypertrophic scar following intralesional use of triamcinolone. Surg Forum. 1973;24:521-523.
3. Shetlar MR, Dobrkovsky M, Linares H, et al. The hypertrophic scar: glycoprotein and collagen components of burn scars. Proc Soc Exp Biol Med. 1971;138:298-300.
4. Ueda K, Furuya E, Yasuda Y, et al. Keloids have continuous high metabolic activity. Plast Reconstr Surg. 1999;104:694-698.
5. Reno F, Sabbatini M, Lombardi F, et al. In vitro mechanical compression induces apoptosis and regulates cytokines release in hypertrophic scars. Wound Repair Regen. 2003;11:331-336.
6. Ueda K, Yasuda Y, Furuya E, et al. Inadequate blood supply persists in keloids. Scand J Plast Reconstr Surg Hand Surg. 2004;38:267-271.
7. Shai A, Maibach H. Natural course of wound repair versus impaired healing in chronic skin ulcers. In: Shai A, Maibach H, eds. Wound Healing and Ulcers of the Skin. Berlin: Springer; 2005:7-17.
8. Kischer CW, Thies AC, Chvapil M. Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids. Hum Pathol. 1982;13:819-824.
9. Shibata M, Qin K, Ichioka S, et al. Vascular wall energetics in arterioles during nitric oxide-dependent and -independent vasodilation. J Appl Physiol. 2006;100:1793-1798.
10. Shibata M, Ichioka S, Kamiya A. Nitric oxide modulates oxygen consumption by arteriolar walls in rat skeletal muscle. Am J Physiol Heart Circ Physiol. 2005;289:H2673-H2679.
11. Semenza GL. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol Med. 2001;7:345-350.
12. Steinbrech DS, Mehrara BJ, Chau D, et al. Hypoxia upregulates VEGF production in keloid fibroblasts. Ann Plast Surg. 1999;42:514-519; discussion 519.