Antifungal efficacy of voriconazole, itraconazole and amphotericin b in experimental fusarium solani keratitis

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 2, 2008, Pages 275-279

  Yavas, Güliz Fatma ^a,c   Öztürk, Faruk ^a   Küsbeci, Tuncay ^a   Çetınkaya, Zafer ^a   Ermis, Sitki Samet ^a   Kiraz, Nuri ^b   Inan, Ümit Übeyt ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Amphotericin B; Fusarium solani; Itraconazole; Keratitis; Voriconazole

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; ITRACONAZOLE; SODIUM CHLORIDE; VORICONAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DISEASE COURSE; DRUG SOLUTION; FUNGUS CULTURE; FUSARIUM SOLANI; KERATOMYCOSIS; MICROBIOLOGICAL EXAMINATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 38549140122     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-007-0687-1     Document Type: Article

References (21)

1. Agarwal PK, Roy P, Das A, Banerjee A, Maity PK, Banerjee AR (2001) Efficacy of topical and systemic itraconazole as a broad-spectrum antifungal agent in mycotic corneal ulcer. A preliminary study. Indian J Ophthalmol 49:173-176
2. Bunya VY, Hammersmith KM, Rapuano CJ, Ayres BD, Cohen EJ (2007) Topical and oral voriconazole in the treatment of fungal keratitis. Am J Ophthalmol 143:151-153
3. Clancy CJ, Nguyen MH (1998) In vitro efficacy and fungicidal activity of voriconazole against Aspergillus and Fusarium species. Eur J Clin Microbiol Infect Dis 17:573-575
4. Diekema DJ, Messer SA, Hollis RJ, Jones RN, Pfaller MA (2003) Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. J Clin Microbiol 41:3623-3626
5. Doczi I, Gyetvai T, Kredics L, Nagy E (2004) Involvement of Fusarium spp in fungal keratitis. Clin Microbiol Infect 10:773-776
6. Durand ML, Kim IK, D'Amico DJ, Loewenstein JI, Tobin EH, Kieval SJ, Martin SS, Azar DT, Miller FS, Lujan BJ, Miller JW (2005) Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin. Am J Ophthalmol 140:552-554
7. Giaconi JA, Marangon FB, Miller D, Alfonso EC (2006) Voriconazole and fungal keratitis: A report of two treatment failures. J Ocul Pharmacol Ther 22:437-439
8. Gopinathan U, Garg P, Fernandes M, Sharma S, Athmanathan S, Rao GN (2002) The epidemiological features and laboratory results of fungal keratitis: A 10-year review at a referral eye care center in south India. Cornea 21:555-559
9. Kalavathy CM, Parmar P, Kaliamurthy J, Philip VR, Ramalingam MD, Jesudasan CA, Thomas PA (2005) Comparison of topical itraconazole 1% with topical natamycin 5% for the treatment of filamentous fungal keratitis. Cornea 24:449-452
10. Klont RR, Eggink CA, Rijs AJMM, Wesseling P, Verweij PE (2005) Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole. Clin Infect Dis 40:110-112
11. Leck AK, Thomas PA, Hagan M, Kaliamurthy J, Ackuaku E, John M, Newman MJ, Codjoe FS, Opintan JA, Kalavathy CM, Essuman V, Jesudasan CA, Johnson GJ (2002) Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis. Br J Ophthalmol 86:1211-1215
12. Lin HC, Chu PH, Kuo YH, Shen SC (2005) Clinical experience in managing Fusarium solani keratitis. Int J Clin Pract 59:549-554
13. Marangon FB, Miller D, Giaconi JA, Alfonso EC (2004) In vitro investigation of voriconazole susceptibility for keratitis and endophthalmitis fungal pathogens. Am J Ophthalmol 137:820-825
14. McLeod S (1999) Fungal Keratitis. In: Yanoff M, Duker JS (eds) Ophthalmology. Mosby, UK, pp 5.10.1-5.10.4
15. Pleyer U, Grammer J, Pleyer JH, Kosmidis P, Friess D, Schmidt KH, Thiel HJ (1995) Amphotericin B-bioavailability in the cornea. Studies with local administration of liposome incorporated amphotericin B. Ophthalmologe 92:469-475
16. Polizzi A, Siniscalchi C, Mastromarino A, Sacca SC (2004) Effect of voriconazole on a corneal abscess caused by fusarium. Acta Ophthalmol Scand 82:762-764
17. Reis A, Sundmacher R, Tintelnot K, Agostini H, Jensen HE, Althaus C (2000) Successful treatment of ocular invasive mould infection (fusariosis) with the new antifungal agent voriconazole. Br J Ophthalmol 84:932-933
18. Schreiber W, Olbrisch A, Vorwerk CK, König W, Behrens-Baumann W (2003) Combined topical fluconazole and corticosteroid treatment for experimental candida albicans keratomycosis. Invest Ophthalmol Vis Sci 44:2634-2643
19. Tzatzarakis MN, Tsatsakis AM, Charvalos E, Vakalounakis D (2001) Comparison of in vitro activities of amphotercin, clotrimazole, econazole, miconazole, and nystatin against fusarium oxysporium. J Environ Sci Health 36:331-340
20. Wingard JR, Leather H (2004) A new era of antifungal therapy. Biol Blood Marrow Transplant 10:73-90
21. Yilmaz S, Maden A (2005) Severe fungal keratitis treated with subconjunctival fluconazole. Am J Ophthalmol 140:454-458