Effect of immunization against ox-LDL with two different antigens on formation and development of atherosclerosis

Lipids in Health and Disease

Volumn 6, Issue , 2007, Pages

  Asgary, Sedigheh ^a   Saberi, Salb Ali ^a   Azampanah, Shirin ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; C REACTIVE PROTEIN; COPPER; GLUCOSE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PHOSPHATE BUFFERED SALINE; TRIACYLGLYCEROL; ANTIGEN; OXIDIZED LOW DENSITY LIPOPROTEIN; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BIOCHEMISTRY; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; CORONARY ARTERY; DRUG BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HYPERCHOLESTEROLEMIA; IMMUNE SYSTEM; IMMUNIZATION; MALE; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; CHEMISTRY; CHOLESTEROL INTAKE; DIET; IMMUNOTHERAPY; METABOLISM; METHODOLOGY; PATHOLOGY; RABBIT; TIME; VACCINATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; ANTIGENS; ATHEROSCLEROSIS; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; COPPER; DIET; HYPERCHOLESTEROLEMIA; IMMUNE SYSTEM; IMMUNOTHERAPY; LIPOPROTEINS, LDL; MALE; OXYGEN; RABBITS; TIME FACTORS; VACCINATION;

EID: 38549134636     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-6-32     Document Type: Article

References (22)

1. Is atherosclerosis an immunologically mediated disease? G Wick A Amberger R Kleindienst Q Xu, Immunol Today 1995 16 27 33 10.1016/0167-5699(95)80067-0 7880386
2. Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. P Libby GK Hansson, Lab Invest 1991 64 5 15 1990208
3. Emerging cross-regulatory roles of immunity and autoimmunity in atherosclerosis. J George D Harats B Gilburd Y Shoenfeld, Immunol Res 1996 15 315 322 8988398
4. Antibodies to oxidized LDL in atherosclerosis development-clinical and animal studies. H Johannes, Clinica chimica Acta 2004 348 1 8 10.1016/j.cccn.2004.05.021
5. Immunomodulation for treatment and prevention of atherosclerosis. Y Sherer Y Shoenfeld, Auto immunity Reviews 2002 1 21 27
6. Immunization of low density lipoprotein receptor deficient (LDL-RD) mice with heart shock protein 65 (HSP-65) promotes early atherosclerosis. A Afek J George B Gilburd L Rauova I Goldberg J Kopolovic, J autoimmunity 2000 14 115 127 10.1006/jaut.1999.0351
7. Cloning monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. W Palinski S Horkko E Miller UP Steinbrecher HC Powell LK Curtiss JL Witztum, J Clin Invest 1996 98 800 814 8698873
8. Low density lipoprotein under-goes oxidative modification in vivo. W Palinski ME Rosenfeld S Yla-Herttuala GC Gurtner SS Socher SW Butler S Parthasarathy TE Carew D Steinberg JL Witztum, proc Natl Acad Sci USA 1989 86 1372 1376 2465552 10.1073/pnas.86.4.1372
9. Rabbi- and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL. S Yla-Herttuaia W Palinski SW Butler S Picard D Steinberg JL Witztum, Arterioscler 1 Thromb 1994 14 32 40
10. Distribution of oxidation specific lipid protein adducts and apolipoprotein B in atherosclerosis lesion of varying severity from WHHL rabbits. ME Rosenfeld W Palinski S Herttuala S Bulter JL Witztum, Arteriosclerosis 1990 10 336 349 1693069
11. Autoantibody against oxidised LDL and, progression of carotid atherosclerosis. JT Salonen S Yla-Herttuala R Yamamoto S Butler H Korpela R Salonen K Nyssonen W Palinski JL Witztum, Lancet 1992 339 883 887 10.1016/0140-6736(92)90926-T 1348295
12. Patients with early-onset peripheral vascular disease have increased levels of auto antibodies against oxidized LDL. C Bergmark R Wu U De faire AK Lefuert SW Edenborg, Arteriovascular thromb Vasc Biol 1995 15 441 445
13. Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon injury in hypercholesterolemic rabbits. J Nilsson F Calara J Regnstrom AH Nilsson S Ameli B Cercek PK Shah, Journal of American college of cardiology 1997 30 7 1886 1891 10.1016/S0735-1097(97)00366-5
14. Separation of plasma lipoproteins by density gradient ultracentrifugation. TG Redgrave DCK Roberts CE West, Anal Biochem 1975 65 42 49 10.1016/0003-2697(75)90488-1 165752
15. The preparation of copper-oxidized LDL for measurement of oxidized LDL antibodies by EIA. M Lopes Virella S Koshinen M Mironova D Horne R Klein C Chasserean C Enockson G Vivella, J Atherosclerosis 2000 152 107 115 10.1016/S0021-9150(99)00456-6
16. Specificity of receptor-mediated recognition of malondialdehyde modified low density lipoproteins. ME Harberland AM Foglemen SP Edwards, Proc Natl Acade Sci 1981 79 1712 1716 10.1073/pnas.79.6.1712
17. Hyperimmunization of apo-E-deficient mice with homologous malondialdehyde low-density lipoprotein suppress:s early atherogenesis. J George A Mek B Gilburd H Levkovitz A Shaish I Goldberg Y Kopolovic G Wick Y Shoenfeld D Harats, Atherosclerosis 1998 138 147 152 10.1016/S0021-9150(98)00015-X 9678780
18. Immunization of low density lipoprotein (LDL) receptor-deficient) rabbits with homologous malondialdehyde modified LDL reduces atherogenesis. W Palinski E Miller JL Witztum, Proc Natl Acad Sci USA 1995 92 821 825 7846059 10.1073/pnas.92.3.821
19. Effect of immunization with homologous LDL, and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits, Arterioscler. S Ameli A Hultgardh-Nilsson J Regnstrom F Calara J Yano B Cercek PK Shah J Nilsson, Thromb Vasco Biol 1996 16 1074 1079 8696949
20. Comparison of C reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. PM Riker N Rifai L Ross JE Buring NR Cook, N Eng J Med 2002 347 1557 1565 10.1056/NEJMoa021993
21. Atheroprotective effect of adjuvants in apolipoprotein E. J Khallou-Laschet, knockout mice Athero 2000 184 330 341 10.1016/j. atherosclerosis.2005.04.021
22. Freunds adjuvant alone is antiatherogenic in apo-E-deficient mice and specific immunization against TNF-X confers no additional benefit. P Hansen M Chew J Zhou A Daugherty N Heegaard P Jensen S Mouritsen E Falk, Athero 2001 158 87 94 10.1016/S0021-9150(01)00418-X