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Volumn 49, Issue 1, 2008, Pages 27-35

The role of TRAIL death receptors in the treatment of hematological malignancies

Author keywords

Apoptosis; Therapy; TRAIL; TRAIL receptors; Transcription

Indexed keywords

ADENOVIRUS VECTOR; ARSENIC TRIOXIDE; BORTEZOMIB; CASPASE 10; CASPASE 8; CHLORAMBUCIL; CISPLATIN; CYTARABINE; DEATH RECEPTOR; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DEPSIPEPTIDE; DOXORUBICIN; ETOPOSIDE; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLAVOPIRIDOL; FLUDARABINE; GAMMA INTERFERON; GEMCITABINE; GLUCOCORTICOID; IMATINIB; LEXATUMUMAB; LONAFARNIB; MAPATUMUMAB; MONOCLONAL ANTIBODY; PEMETREXED; RITUXIMAB; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG;

EID: 38549132880     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190701713655     Document Type: Review
Times cited : (40)

References (66)
  • 1
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A. and Dixit, V. M. (1998) Death receptors: Signaling and modulation. Science, 281, pp. 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 2
    • 28544439923 scopus 로고    scopus 로고
    • On the TRAIL of a new therapy for leukemia
    • Kaufmann, S. H. and Steensma, D. P. (2005) On the TRAIL of a new therapy for leukemia. Leukemia, 19, pp. 2195-2202.
    • (2005) Leukemia , vol.19 , pp. 2195-2202
    • Kaufmann, S.H.1    Steensma, D.P.2
  • 4
    • 3342894130 scopus 로고    scopus 로고
    • Targeting death receptors in cancer with Apo2L/TRAIL
    • Kelley, S. K. and Ashkenazi, A. (2004) Targeting death receptors in cancer with Apo2L/TRAIL. Curr Opin Pharmacol, 4, pp. 333-339.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 333-339
    • Kelley, S.K.1    Ashkenazi, A.2
  • 5
    • 3042822074 scopus 로고    scopus 로고
    • Monoclonal antibodies against TRAIL
    • Liabakk, N. B. and Espevik, T. (2004) Monoclonal antibodies against TRAIL. Vitam Horm, 67, pp. 65-79.
    • (2004) Vitam Horm , vol.67 , pp. 65-79
    • Liabakk, N.B.1    Espevik, T.2
  • 6
    • 0032910169 scopus 로고    scopus 로고
    • Apoptosis control by death and decoy receptors
    • Ashkenazi, A. and Dixit, V. M. (1999) Apoptosis control by death and decoy receptors. Curr Opin Cell Biol, 11, pp. 255-260.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 255-260
    • Ashkenazi, A.1    Dixit, V.M.2
  • 7
    • 1542409979 scopus 로고    scopus 로고
    • Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications
    • Kabore, A. F., Johnston, J. B. and Gibson, S. B. (2004) Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications. Curr Cancer Drug Targets, 4, pp. 147-163.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 147-163
    • Kabore, A.F.1    Johnston, J.B.2    Gibson, S.B.3
  • 8
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
    • Schneider, P., Thome, M., Burns, K., Bodmer, J. L., Hofmann, K. and Kataoka, T. (1997) TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity, 7, pp. 831-836.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thome, M.2    Burns, K.3    Bodmer, J.L.4    Hofmann, K.5    Kataoka, T.6
  • 9
    • 0036792643 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines
    • Shetty, S., Gladden, J. B., Henson, E. S., Hu, X., Villanueva, J. and Haney, N. (2002) Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines. Apoptosis, 7, pp. 413-420.
    • (2002) Apoptosis , vol.7 , pp. 413-420
    • Shetty, S.1    Gladden, J.B.2    Henson, E.S.3    Hu, X.4    Villanueva, J.5    Haney, N.6
  • 10
    • 3042743700 scopus 로고    scopus 로고
    • Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors
    • Aggarwal, B. B., Bhardwaj, U. and Takada, Y. (2004) Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors. Vitam Horm, 67, pp. 453-483.
    • (2004) Vitam Horm , vol.67 , pp. 453-483
    • Aggarwal, B.B.1    Bhardwaj, U.2    Takada, Y.3
  • 11
    • 7544245975 scopus 로고    scopus 로고
    • Emerging non-apoptotic functions of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L
    • Pietro, R Di and Zauli, G. (2004) Emerging non-apoptotic functions of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L. J Cell Physiol, 201, pp. 331-340.
    • (2004) J Cell Physiol , vol.201 , pp. 331-340
    • Pietro, R.1    Di Zauli, G.2
  • 12
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • Kim, K., Fisher, M. J., Xu, S. Q. and el-Deiry, W. S. (2000) Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res, 6, pp. 335-346.
    • (2000) Clin Cancer Res , vol.6 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.Q.3    el-Deiry, W.S.4
  • 13
    • 0037015675 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
    • MacFarlane, M., Harper, N., Snowden, R. T., Dyer, M. J., Barnett, G. A. and Pringle, J. H. (2002) Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene, 21, pp. 6809-6818.
    • (2002) Oncogene , vol.21 , pp. 6809-6818
    • MacFarlane, M.1    Harper, N.2    Snowden, R.T.3    Dyer, M.J.4    Barnett, G.A.5    Pringle, J.H.6
  • 14
    • 34250029013 scopus 로고    scopus 로고
    • Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL
    • Gomez-Benito, M., Martinez-Lorenzo, M. J., Anel, A., Marzo, I. and Naval, J. (2007) Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/ TRAIL. Exp Cell Res, 313, pp. 2378-2388.
    • (2007) Exp Cell Res , vol.313 , pp. 2378-2388
    • Gomez-Benito, M.1    Martinez-Lorenzo, M.J.2    Anel, A.3    Marzo, I.4    Naval, J.5
  • 15
    • 24044439753 scopus 로고    scopus 로고
    • Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily
    • Remacle-Bonnet, M., Garrouste, F., Baillat, G., Andre, F., Marvaldi, J. and Pommier, G. (2005) Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily. Am J Pathol, 167, pp. 761-773.
    • (2005) Am J Pathol , vol.167 , pp. 761-773
    • Remacle-Bonnet, M.1    Garrouste, F.2    Baillat, G.3    Andre, F.4    Marvaldi, J.5    Pommier, G.6
  • 16
    • 14844345670 scopus 로고    scopus 로고
    • Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts
    • Vanoosten, R. L., Moore, J. M., Ludwig, A. T. and Griffith, T. S. (2005) Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Mol Ther, 11, pp. 542-552.
    • (2005) Mol Ther , vol.11 , pp. 542-552
    • Vanoosten, R.L.1    Moore, J.M.2    Ludwig, A.T.3    Griffith, T.S.4
  • 17
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • Delmas, D., Rebe, C., Micheau, O., Athias, A., Gambert, P. and Grazide, S. (2004) Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene, 23, pp. 8979-8986.
    • (2004) Oncogene , vol.23 , pp. 8979-8986
    • Delmas, D.1    Rebe, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6
  • 18
    • 6344246456 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL): A potential candidate for combined treatment of hematological malignancies
    • Secchiero, P., Vaccarezza, M., Gonelli, A. and Zauli, G. (2004) TNF-related apoptosis-inducing ligand (TRAIL): A potential candidate for combined treatment of hematological malignancies. Curr Pharm Des, 10, pp. 3673-3681.
    • (2004) Curr Pharm Des , vol.10 , pp. 3673-3681
    • Secchiero, P.1    Vaccarezza, M.2    Gonelli, A.3    Zauli, G.4
  • 19
    • 33749164762 scopus 로고    scopus 로고
    • Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
    • Merino, D., Lalaoui, N., Morizot, A., Schneider, P., Solary, E. and Micheau, O. (2006) Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol, 26, pp. 7046-7055.
    • (2006) Mol Cell Biol , vol.26 , pp. 7046-7055
    • Merino, D.1    Lalaoui, N.2    Morizot, A.3    Schneider, P.4    Solary, E.5    Micheau, O.6
  • 20
    • 0032522463 scopus 로고    scopus 로고
    • p53-dependent and -independent regulation of the death receptor KILLER/ DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
    • Sheikh, M. S., Burns, T. F., Huang, Y., Wu, G. S., Amundson, S. and Brooks, K. S. (1998) p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res, 58, pp. 1593-1598.
    • (1998) Cancer Res , vol.58 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3    Wu, G.S.4    Amundson, S.5    Brooks, K.S.6
  • 21
    • 0034732258 scopus 로고    scopus 로고
    • Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
    • Takimoto, R. and El-Deiry, W. S. (2000) Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene, 19, pp. 1735-1743.
    • (2000) Oncogene , vol.19 , pp. 1735-1743
    • Takimoto, R.1    El-Deiry, W.S.2
  • 22
    • 0034551746 scopus 로고    scopus 로고
    • Antileukemic drugs increase death receptor 5 levels and enhance apo-2L-induced apoptosis of human acute leukemia cells
    • Wen, J., Ramadevi, N., Nguyen, D., Perkins, C., Worthington, E. and Bhalla, K. (2000) Antileukemic drugs increase death receptor 5 levels and enhance apo-2L-induced apoptosis of human acute leukemia cells. Blood, 96, pp. 3900-3906.
    • (2000) Blood , vol.96 , pp. 3900-3906
    • Wen, J.1    Ramadevi, N.2    Nguyen, D.3    Perkins, C.4    Worthington, E.5    Bhalla, K.6
  • 23
    • 0344441904 scopus 로고    scopus 로고
    • Role of the TRAIL/APO2-L death receptors in chlorambucil- and fludarabine-induced apoptosis in chronic lymphocytic leukemia
    • Johnston, J. B., Kabore, A. F., Strutinsky, J., Hu, X., Paul, J. T. and Kropp, D. M. (2003) Role of the TRAIL/APO2-L death receptors in chlorambucil- and fludarabine-induced apoptosis in chronic lymphocytic leukemia. Oncogene, 22, pp. 8356-8369.
    • (2003) Oncogene , vol.22 , pp. 8356-8369
    • Johnston, J.B.1    Kabore, A.F.2    Strutinsky, J.3    Hu, X.4    Paul, J.T.5    Kropp, D.M.6
  • 24
    • 0035862189 scopus 로고    scopus 로고
    • p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-γ
    • Meng, R. D. and El-Deiry, W. S. (2001) p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-γ. Exp Cell Res, 262, pp. 154-169.
    • (2001) Exp Cell Res , vol.262 , pp. 154-169
    • Meng, R.D.1    El-Deiry, W.S.2
  • 25
    • 0033989422 scopus 로고    scopus 로고
    • Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
    • Gibson, S. B., Oyer, R., Spalding, A. C., Anderson, S. M. and Johnson, G. L. (2000) Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol Cell Biol, 20, pp. 205-212.
    • (2000) Mol Cell Biol , vol.20 , pp. 205-212
    • Gibson, S.B.1    Oyer, R.2    Spalding, A.C.3    Anderson, S.M.4    Johnson, G.L.5
  • 26
    • 0036792643 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines
    • Shetty, S., Gladden, J. B., Henson, E. S., Hu, X., Villanueva, J. and Haney, N. (2002) Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFκB activation in epithelial derived cell lines. Apoptosis, 7, pp. 413-420.
    • (2002) Apoptosis , vol.7 , pp. 413-420
    • Shetty, S.1    Gladden, J.B.2    Henson, E.S.3    Hu, X.4    Villanueva, J.5    Haney, N.6
  • 27
    • 0035798180 scopus 로고    scopus 로고
    • Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene
    • Yoshida, T., Maeda, A., Tani, N. and Sakai, T. (2001) Promoter structure and transcription initiation sites of the human death receptor 5/ TRAIL-R2 gene. FEBS Lett, 507, pp. 381-385.
    • (2001) FEBS Lett , vol.507 , pp. 381-385
    • Yoshida, T.1    Maeda, A.2    Tani, N.3    Sakai, T.4
  • 28
    • 20744433491 scopus 로고    scopus 로고
    • Transcription factor NF-κB differentially regulates death receptor 5 expression involving histone deacetylase 1
    • Shetty, S., Graham, B. A., Brown, J. G., Hu, X., Vegh-Yarema, N. and Harding, G. (2005) Transcription factor NF-κB differentially regulates death receptor 5 expression involving histone deacetylase 1. Mol Cell Biol, 25, pp. 5404-5416.
    • (2005) Mol Cell Biol , vol.25 , pp. 5404-5416
    • Shetty, S.1    Graham, B.A.2    Brown, J.G.3    Hu, X.4    Vegh-Yarema, N.5    Harding, G.6
  • 29
    • 5644258322 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate in human lung cancer cells
    • Zou, W., Liu, X., Yue, P., Zhou, Z., Sporn, M. B. and Lotan, R. (2004) c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate in human lung cancer cells. Cancer Res, 64, pp. 7570-7578.
    • (2004) Cancer Res , vol.64 , pp. 7570-7578
    • Zou, W.1    Liu, X.2    Yue, P.3    Zhou, Z.4    Sporn, M.B.5    Lotan, R.6
  • 30
    • 2342495721 scopus 로고    scopus 로고
    • Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway
    • Wang, Y., Engels, I. H., Knee, D. A., Nasoff, M., Deveraux, Q. L. and Quon, K. C. (2004) Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway. Cancer Cell, 5, pp. 501-512.
    • (2004) Cancer Cell , vol.5 , pp. 501-512
    • Wang, Y.1    Engels, I.H.2    Knee, D.A.3    Nasoff, M.4    Deveraux, Q.L.5    Quon, K.C.6
  • 31
    • 34547112563 scopus 로고    scopus 로고
    • The farnesyltransferase inhibitor Lonafarnib induce CHOP-dependent expression of death receptor 5 leading to induction of apoptosis in human cancer cells
    • Sun, S. Y., Liu, X., Zou, W., Yue, P., Marcus, A. I. and Khuri, F. R. (2007) The farnesyltransferase inhibitor Lonafarnib induce CHOP-dependent expression of death receptor 5 leading to induction of apoptosis in human cancer cells. J Biol Chem, 282, pp. 18800-18809.
    • (2007) J Biol Chem , vol.282 , pp. 18800-18809
    • Sun, S.Y.1    Liu, X.2    Zou, W.3    Yue, P.4    Marcus, A.I.5    Khuri, F.R.6
  • 32
    • 6444242600 scopus 로고    scopus 로고
    • Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells
    • Kim, Y. H., Park, J. W., Lee, J. Y. and Kwon, T. K. (2004) Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells. Carcinogenesis, 25, pp. 1813-1820.
    • (2004) Carcinogenesis , vol.25 , pp. 1813-1820
    • Kim, Y.H.1    Park, J.W.2    Lee, J.Y.3    Kwon, T.K.4
  • 33
    • 34147157918 scopus 로고    scopus 로고
    • Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: Up-regulation of DR5 and inhibition of Yin Yang 1
    • Baritaki, S., Huerta-Yepez, S., Sakai, T., Spandidos, D. A. and Bonavida, B. (2007) Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: Up-regulation of DR5 and inhibition of Yin Yang 1. Mol Cancer Ther, 6, pp. 1387-1399.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1387-1399
    • Baritaki, S.1    Huerta-Yepez, S.2    Sakai, T.3    Spandidos, D.A.4    Bonavida, B.5
  • 34
    • 0037046509 scopus 로고    scopus 로고
    • Evidence that the human death receptor 4 is regulated by activator protein 1
    • Guan, B., Yue, P., Lotan, R. and Sun, S. Y. (2002) Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene, 21, pp. 3121-3129.
    • (2002) Oncogene , vol.21 , pp. 3121-3129
    • Guan, B.1    Yue, P.2    Lotan, R.3    Sun, S.Y.4
  • 35
    • 0035008833 scopus 로고    scopus 로고
    • Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene
    • Guan, B., Yue, P., Clayman, G. L. and Sun, S. Y. (2001) Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J Cell Physiol, 188, pp. 98-105.
    • (2001) J Cell Physiol , vol.188 , pp. 98-105
    • Guan, B.1    Yue, P.2    Clayman, G.L.3    Sun, S.Y.4
  • 36
    • 0034527878 scopus 로고    scopus 로고
    • Immunologically-mediated tumour cell apoptosis: The role of TRAIL in T cell and cytokine-mediated responses to melanoma
    • Nguyen, T., Thomas, W., Zhang, X. D., Gray, C. and Hersey, P. (2000) Immunologically-mediated tumour cell apoptosis: The role of TRAIL in T cell and cytokine-mediated responses to melanoma. Forum (Genova), 10, pp. 243-252.
    • (2000) Forum (Genova) , vol.10 , pp. 243-252
    • Nguyen, T.1    Thomas, W.2    Zhang, X.D.3    Gray, C.4    Hersey, P.5
  • 37
    • 33745854287 scopus 로고    scopus 로고
    • The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology
    • Zauli, G. and Secchiero, P. (2006) The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology. Cytokine Growth Factor Rev, 17, pp. 245-257.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 245-257
    • Zauli, G.1    Secchiero, P.2
  • 38
    • 0036687185 scopus 로고    scopus 로고
    • Characterization of the in vivo function of TNF-α-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice
    • Sedger, L. M., Glaccum, M. B., Schuh, J. C., Kanaly, S. T., Williamson, E. and Kayagaki, N. (2002) Characterization of the in vivo function of TNF-α-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/ Apo2L gene-deficient mice. Eur J Immunol, 32, pp. 2246-2254.
    • (2002) Eur J Immunol , vol.32 , pp. 2246-2254
    • Sedger, L.M.1    Glaccum, M.B.2    Schuh, J.C.3    Kanaly, S.T.4    Williamson, E.5    Kayagaki, N.6
  • 39
    • 27644577006 scopus 로고    scopus 로고
    • Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes
    • Rubio-Moscardo, F., Blesa, D., Mestre, C., Siebert, R., Balasas, T. and Benito, A. (2005) Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes. Blood, 106, pp. 3214-3222.
    • (2005) Blood , vol.106 , pp. 3214-3222
    • Rubio-Moscardo, F.1    Blesa, D.2    Mestre, C.3    Siebert, R.4    Balasas, T.5    Benito, A.6
  • 40
    • 0001130662 scopus 로고    scopus 로고
    • Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
    • Lee, S. H., Shin, M. S., Kim, H. S., Lee, H. K., Park, W. S. and Kim, S. Y. (1999) Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res, 59, pp. 5683-5686.
    • (1999) Cancer Res , vol.59 , pp. 5683-5686
    • Lee, S.H.1    Shin, M.S.2    Kim, H.S.3    Lee, H.K.4    Park, W.S.5    Kim, S.Y.6
  • 41
    • 17744364468 scopus 로고    scopus 로고
    • Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
    • Lee, S. H., Shin, M. S., Kim, H. S., Lee, H. K., Park, W. S. and Kim, S. Y. (2001) Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene, 20, pp. 399-403.
    • (2001) Oncogene , vol.20 , pp. 399-403
    • Lee, S.H.1    Shin, M.S.2    Kim, H.S.3    Lee, H.K.4    Park, W.S.5    Kim, S.Y.6
  • 42
    • 17144392555 scopus 로고    scopus 로고
    • Absence of gene mutation in TRAIL receptor 1 (TRAIL-R1) and TRAIL receptor 2 (TRAIL-R2) in chronic myelogenous leukemia and myelodysplastic syndrome, and analysis of mRNA Expressions of TRAIL and TRAIL-related genes in chronic myelogenous leukemia
    • Liu, L. G., Tanaka, H., Ito, K., Ito, T., Sultana, T. A. and Kyo, T. (2005) Absence of gene mutation in TRAIL receptor 1 (TRAIL-R1) and TRAIL receptor 2 (TRAIL-R2) in chronic myelogenous leukemia and myelodysplastic syndrome, and analysis of mRNA Expressions of TRAIL and TRAIL-related genes in chronic myelogenous leukemia. Acta Haematol, 113, pp. 113-123.
    • (2005) Acta Haematol , vol.113 , pp. 113-123
    • Liu, L.G.1    Tanaka, H.2    Ito, K.3    Ito, T.4    Sultana, T.A.5    Kyo, T.6
  • 43
    • 33644850571 scopus 로고    scopus 로고
    • Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer
    • Wolf, S., Mertens, D., Pscherer, A., Schroeter, P., Winkler, D. and Grone, H. J. (2006) Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer. Int J Cancer, 118, pp. 1831-1835.
    • (2006) Int J Cancer , vol.118 , pp. 1831-1835
    • Wolf, S.1    Mertens, D.2    Pscherer, A.3    Schroeter, P.4    Winkler, D.5    Grone, H.J.6
  • 44
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • Zhang, L. and Fang, B. (2005) Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther, 12, pp. 228-237.
    • (2005) Cancer Gene Ther , vol.12 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 46
    • 0036720390 scopus 로고    scopus 로고
    • Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1
    • Pedersen, I. M., Kitada, S., Leoni, L. M., Zapata, J. M., Karras, J. G. and Tsukada, N. (2002) Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1. Blood, 100, pp. 1795-1801.
    • (2002) Blood , vol.100 , pp. 1795-1801
    • Pedersen, I.M.1    Kitada, S.2    Leoni, L.M.3    Zapata, J.M.4    Karras, J.G.5    Tsukada, N.6
  • 47
    • 0347416908 scopus 로고    scopus 로고
    • Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia
    • Saxena, A., Viswanathan, S., Moshynska, O., Tandon, P., Sankaran, K. and Sheridan, D. P. (2004) Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. Am J Hematol, 75, pp. 22-33.
    • (2004) Am J Hematol , vol.75 , pp. 22-33
    • Saxena, A.1    Viswanathan, S.2    Moshynska, O.3    Tandon, P.4    Sankaran, K.5    Sheridan, D.P.6
  • 48
    • 4544348358 scopus 로고    scopus 로고
    • Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia
    • Johnston, J. B., Paul, J. T., Neufeld, N. J., Haney, N., Kropp, D. M. and Hu, X. (2004) Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia. Leuk Lymphoma, 45, pp. 2017-2027.
    • (2004) Leuk Lymphoma , vol.45 , pp. 2017-2027
    • Johnston, J.B.1    Paul, J.T.2    Neufeld, N.J.3    Haney, N.4    Kropp, D.M.5    Hu, X.6
  • 49
    • 22344456263 scopus 로고    scopus 로고
    • BH3-only proteins in control: Specificity regulates MCL-1 and BAK-mediated apoptosis
    • Gelinas, C. and White, E. (2005) BH3-only proteins in control: specificity regulates MCL-1 and BAK-mediated apoptosis. Genes Dev, 19, pp. 1263-1268.
    • (2005) Genes Dev , vol.19 , pp. 1263-1268
    • Gelinas, C.1    White, E.2
  • 50
    • 9144234147 scopus 로고    scopus 로고
    • TRAIL and its receptors as targets for cancer therapy
    • Yagita, H., Takeda, K., Hayakawa, Y., Smyth, M. J. and Okumura, K. (2004) TRAIL and its receptors as targets for cancer therapy. Cancer Sci, 95, pp. 777-783.
    • (2004) Cancer Sci , vol.95 , pp. 777-783
    • Yagita, H.1    Takeda, K.2    Hayakawa, Y.3    Smyth, M.J.4    Okumura, K.5
  • 51
    • 33847726589 scopus 로고    scopus 로고
    • Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
    • Shrader, M., Pino, M. S., Lashinger, L., Bar-Eli, M., Adam, L. and Dinney, C. P. (2007) Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res, 67, pp. 1430-1435.
    • (2007) Cancer Res , vol.67 , pp. 1430-1435
    • Shrader, M.1    Pino, M.S.2    Lashinger, L.3    Bar-Eli, M.4    Adam, L.5    Dinney, C.P.6
  • 52
    • 0346792725 scopus 로고    scopus 로고
    • TRAIL and apoptosis induction by TNF-family death receptors
    • Wang, S. and El-Deiry, W. S. (2003) TRAIL and apoptosis induction by TNF-family death receptors. Oncogene, 22, pp. 8628-8633.
    • (2003) Oncogene , vol.22 , pp. 8628-8633
    • Wang, S.1    El-Deiry, W.S.2
  • 53
    • 33845191515 scopus 로고    scopus 로고
    • Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites
    • Lee, T. J., Jung, E. M., Lee, J. T., Kim, S., Park, J. W. and Choi, K. S. (2006) Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites. Mol Cancer Ther, 5, pp. 2737-2746.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2737-2746
    • Lee, T.J.1    Jung, E.M.2    Lee, J.T.3    Kim, S.4    Park, J.W.5    Choi, K.S.6
  • 54
    • 0037311226 scopus 로고    scopus 로고
    • Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-α or TNF-related apoptosis-inducing ligand in human cancer cell lines
    • Kim, D. M., Koo, S. Y., Jeon, K., Kim, M. H., Lee, J. and Hong, C. Y. (2003) Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-α or TNF-related apoptosis-inducing ligand in human cancer cell lines. Cancer Res, 63, pp. 621-626.
    • (2003) Cancer Res , vol.63 , pp. 621-626
    • Kim, D.M.1    Koo, S.Y.2    Jeon, K.3    Kim, M.H.4    Lee, J.5    Hong, C.Y.6
  • 55
    • 2342624727 scopus 로고    scopus 로고
    • Arsenic trioxide selectively induces early and extensive apoptosis via the APO2/caspase-8 pathway engaging the mitochondrial pathway in myeloma cells with mutant p53
    • Akay, C. and Gazitt, Y. (2003) Arsenic trioxide selectively induces early and extensive apoptosis via the APO2/caspase-8 pathway engaging the mitochondrial pathway in myeloma cells with mutant p53. Cell Cycle, 2, pp. 358-368.
    • (2003) Cell Cycle , vol.2 , pp. 358-368
    • Akay, C.1    Gazitt, Y.2
  • 56
    • 0037772194 scopus 로고    scopus 로고
    • Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL
    • Liu, Q., Hilsenbeck, S. and Gazitt, Y. (2003) Arsenic trioxide-induced apoptosis in myeloma cells: P53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL. Blood, 101, pp. 4078-4087.
    • (2003) Blood , vol.101 , pp. 4078-4087
    • Liu, Q.1    Hilsenbeck, S.2    Gazitt, Y.3
  • 57
    • 0035126944 scopus 로고    scopus 로고
    • Cotreatment with STI-571 enhances tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
    • Nimmanapalli, R., Porosnicu, M., Nguyen, D., Worthington, E., O'Bryan, E. and Perkins, C. (2001) Cotreatment with STI-571 enhances tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin Cancer Res, 7, pp. 350-357.
    • (2001) Clin Cancer Res , vol.7 , pp. 350-357
    • Nimmanapalli, R.1    Porosnicu, M.2    Nguyen, D.3    Worthington, E.4    O'Bryan, E.5    Perkins, C.6
  • 58
    • 33745810978 scopus 로고    scopus 로고
    • The TRAIL apoptotic pathway mediates proteasome inhibitor induced apoptosis in primary chronic lymphocytic leukemia cells
    • Kabore, A. F., Sun, J., Hu, X., McCrea, K., Johnston, J. B. and Gibson, S. (2006) The TRAIL apoptotic pathway mediates proteasome inhibitor induced apoptosis in primary chronic lymphocytic leukemia cells. Apoptosis, 11, pp. 1175-1193.
    • (2006) Apoptosis , vol.11 , pp. 1175-1193
    • Kabore, A.F.1    Sun, J.2    Hu, X.3    McCrea, K.4    Johnston, J.B.5    Gibson, S.6
  • 60
    • 13444274622 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
    • Insinga, A., Monestiroli, S., Ronzoni, S., Gelmetti, V., Marchesi, F. and Viale, A. (2005) Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat Med, 11, pp. 71-76.
    • (2005) Nat Med , vol.11 , pp. 71-76
    • Insinga, A.1    Monestiroli, S.2    Ronzoni, S.3    Gelmetti, V.4    Marchesi, F.5    Viale, A.6
  • 61
    • 34648831679 scopus 로고    scopus 로고
    • Synergistic induction of tumor cell death by combining cisplatin with an oncolytic adenovirus carrying TRAIL
    • Pan, Q., Liu, B., Liu, J., Cai, R., Wang, Y. and Qian, C. (2007) Synergistic induction of tumor cell death by combining cisplatin with an oncolytic adenovirus carrying TRAIL. Mol Cell Biochem, 304, pp. 315-323.
    • (2007) Mol Cell Biochem , vol.304 , pp. 315-323
    • Pan, Q.1    Liu, B.2    Liu, J.3    Cai, R.4    Wang, Y.5    Qian, C.6
  • 63
    • 37149035841 scopus 로고    scopus 로고
    • A phase 1B safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low grade non-Hodgkin lymphoma
    • Abstract
    • Yee, L., Fanale, M., Dimick, K., Calvert, S., Robbins, C. and Ing, J. (2007) A phase 1B safety and pharmacokinetic (PK) study of recombinant human Apo2L/TRAIL in combination with rituximab in patients with low grade non-Hodgkin lymphoma. p. Abstract 8078.
    • (2007) , pp. 8078
    • Yee, L.1    Fanale, M.2    Dimick, K.3    Calvert, S.4    Robbins, C.5    Ing, J.6
  • 64
    • 24944458177 scopus 로고    scopus 로고
    • Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death
    • Georgakis, G. V., Li, Y., Humphreys, R., Andreeff, M., O'Brien, S. and Younes, M. (2005) Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death. Br J Haematol, 130, pp. 501-510.
    • (2005) Br J Haematol , vol.130 , pp. 501-510
    • Georgakis, G.V.1    Li, Y.2    Humphreys, R.3    Andreeff, M.4    O'Brien, S.5    Younes, M.6
  • 65
    • 38549176747 scopus 로고    scopus 로고
    • A phase 1b study to access the safety of lexatumumab, a human monoclonal antibody that activates TRAIL-R2 in combination with gemitabine, pemetrexed, doxorubicin, or FOLFIRI
    • Abstract
    • Skic, B. I., Wakelee, H. A., Mehren, M. V., Lewis, N., Calvert, A. H. and Plummer, E. R. (2007) A phase 1b study to access the safety of lexatumumab, a human monoclonal antibody that activates TRAIL-R2 in combination with gemitabine, pemetrexed, doxorubicin, or FOLFIRI. p. Abstract 14006.
    • (2007) , pp. 14006
    • Sikic, B.I.1    Wakelee, H.A.2    Mehren, M.V.3    Lewis, N.4    Calvert, A.H.5    Plummer, E.R.6
  • 66
    • 33947246465 scopus 로고    scopus 로고
    • Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma
    • Fanale, M. A. and Younes, A. (2007) Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma. Drugs, 67, pp. 333-350.
    • (2007) Drugs , vol.67 , pp. 333-350
    • Fanale, M.A.1    Younes, A.2


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