-
1
-
-
0029644482
-
investigators: Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
-
International Multicentric Pooled Analysis of Colon Cancer Trials IMPACT
-
International Multicentric Pooled Analysis of Colon Cancer Trials (IMPACT) investigators: Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 345:939-944, 1995.
-
(1995)
Lancet
, vol.345
, pp. 939-944
-
-
-
2
-
-
0032950293
-
Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer
-
International Multicentric Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) investigators
-
International Multicentric Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) investigators: Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. J. Clin. Oncol. 17: 1356-1363, 1999.
-
(1999)
J. Clin. Oncol
, vol.17
, pp. 1356-1363
-
-
-
3
-
-
2542615200
-
Multicenter International Study of Oxaliplatin/5-Fluorouracil/ Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators: Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
Andre T., Boni C., Mounedji-Boudiaf L., Navarro M., Tabernero J., Hickish T., Topham C., Zaninelli M., Clingan P., Bridgewater J., Tabah-Fisch I., de Gramont A.: Multicenter International Study of Oxaliplatin/5-Fluorouracil/ Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators: Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N. Engl. J. Med. 350:2343-2351, 2004.
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 2343-2351
-
-
Andre, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
Navarro, M.4
Tabernero, J.5
Hickish, T.6
Topham, C.7
Zaninelli, M.8
Clingan, P.9
Bridgewater, J.10
Tabah-Fisch, I.11
de Gramont, A.12
-
4
-
-
33646443236
-
Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: Results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06
-
Lembersky B.C., Wieand H.S., Petrelli N.J., O'Connell M.J., Colangelo L.H., Smith R.E., Seay T.E., Giguere J.K., Marshall M.E., Jacobs A.D., Colman L.K., Soran A., Yothers G., Wolmark N.: Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project Protocol C-06. J. Clin. Oncol. 24:2059-2064, 2006.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 2059-2064
-
-
Lembersky, B.C.1
Wieand, H.S.2
Petrelli, N.J.3
O'Connell, M.J.4
Colangelo, L.H.5
Smith, R.E.6
Seay, T.E.7
Giguere, J.K.8
Marshall, M.E.9
Jacobs, A.D.10
Colman, L.K.11
Soran, A.12
Yothers, G.13
Wolmark, N.14
-
5
-
-
21244497388
-
-
rd, Carrato A., Cassidy J., Cervantes A., Fagerberg J., Georgoulias V., Husseini F., Jodrell D., Koralewski P., Kroning H., Maroun J., Marschner N., McKendrick J., Pawlicki M., Rosso R., Schuller J., Seitz J.F., Stabuc B., Tujakowski J., Van Hazel G., Zaluski J., Scheithauer W.: Capecitabine as adjuvant treatment for stage III colon cancer. N. Engl. J. Med. 352:2696-2704, 2005.
-
rd, Carrato A., Cassidy J., Cervantes A., Fagerberg J., Georgoulias V., Husseini F., Jodrell D., Koralewski P., Kroning H., Maroun J., Marschner N., McKendrick J., Pawlicki M., Rosso R., Schuller J., Seitz J.F., Stabuc B., Tujakowski J., Van Hazel G., Zaluski J., Scheithauer W.: Capecitabine as adjuvant treatment for stage III colon cancer. N. Engl. J. Med. 352:2696-2704, 2005.
-
-
-
-
6
-
-
1442265952
-
-
Meta-Analysis Group of the Japanese Society for Cancer of the Colon and Rectum and the Meta-Analysis Group in Cancer. Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. J. Clin. Oncol. 22:484-492, 2004
-
Meta-Analysis Group of the Japanese Society for Cancer of the Colon and Rectum and the Meta-Analysis Group in Cancer. Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. J. Clin. Oncol. 22:484-492, 2004.
-
-
-
-
7
-
-
32544460436
-
The MMP-9 expression determined the efficacy ofpostoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer
-
Ogata Y., Matono K., Sasatomi T., Ishibashi N., Ohkita A., Mizobe T., Ogo S., Ikeda S., Ozasa H., Shirouzu K.: The MMP-9 expression determined the efficacy ofpostoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. Cancer Chemother. Pharmacol. 57:577-583, 2006.
-
(2006)
Cancer Chemother. Pharmacol
, vol.57
, pp. 577-583
-
-
Ogata, Y.1
Matono, K.2
Sasatomi, T.3
Ishibashi, N.4
Ohkita, A.5
Mizobe, T.6
Ogo, S.7
Ikeda, S.8
Ozasa, H.9
Shirouzu, K.10
-
9
-
-
0027194943
-
(CPT-11 Gastrointestinal Cancer Study Group): Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
-
Shimada Y., Yoshino M., Wakui A., Nakao I., Futatsuki K., Sakata Y., Kambe M., Taguchi T., Ogawa N.: (CPT-11 Gastrointestinal Cancer Study Group): Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. J. Clin.Oncol. 11:909-913, 1993.
-
(1993)
J. Clin.Oncol
, vol.11
, pp. 909-913
-
-
Shimada, Y.1
Yoshino, M.2
Wakui, A.3
Nakao, I.4
Futatsuki, K.5
Sakata, Y.6
Kambe, M.7
Taguchi, T.8
Ogawa, N.9
-
10
-
-
0033558004
-
A multicenter, phase II trial of weekly irinotecan (CPT-11) in patients with previously treated colorectal carcinoma
-
Rothenberg M.L., Cox J.V., deVore R.F., Hainsworth J.D., Pazdur R., Rivkin S.E., Macdonald J.S., Geyer C.E. Jr, Sandbach J., Wolf D.L., Mohrland J.S., Elfring G.L., Miller L.L., Von Hoff D.D.: A multicenter, phase II trial of weekly irinotecan (CPT-11) in patients with previously treated colorectal carcinoma. Cancer 85:786-795, 1999.
-
(1999)
Cancer
, vol.85
, pp. 786-795
-
-
Rothenberg, M.L.1
Cox, J.V.2
deVore, R.F.3
Hainsworth, J.D.4
Pazdur, R.5
Rivkin, S.E.6
Macdonald, J.S.7
Geyer Jr, C.E.8
Sandbach, J.9
Wolf, D.L.10
Mohrland, J.S.11
Elfring, G.L.12
Miller, L.L.13
Von Hoff, D.D.14
-
11
-
-
0034727063
-
(Irinotecan Study Group): Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Saltz L.B., Cox J.V., Blanke C., Rosen L.S., Fehrenbacher L., Moore M.J., Maroun J.A., Ackland S.P., Locker P.K., Pirotta N., Elfring G.L., Miller L.L.: (Irinotecan Study Group): Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 343:905-914, 2000.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
Maroun, J.A.7
Ackland, S.P.8
Locker, P.K.9
Pirotta, N.10
Elfring, G.L.11
Miller, L.L.12
-
12
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard J.Y., Cunningham D., Roth A.D., Navarro M., Jemes R.D., Karasek P., Jandik P., Iveson T., Carmichael J., Arakl M., Gruia G., Awad L., Rougier P.: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 355:1041-1047, 2000.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
Jemes, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Arakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
13
-
-
38549153917
-
-
Ychou M., Raoul J., Douillard J., Bugat R., Mineur L., Viret F., Becouarn Y., Bouche O., Jacob J., Gourgou-Bourgade S. for the GI Group of the FNCLCC and the FFCD: A phase III randomized trial of LV5FU2+CPT-11 vs LV5FU2 alone in adjuvant high risk colon cancer (FNCLCC Accord 02/FFCD 9802). J. Clin. Oncol. 23: (Suppl) abstract 3502, 2005.
-
Ychou M., Raoul J., Douillard J., Bugat R., Mineur L., Viret F., Becouarn Y., Bouche O., Jacob J., Gourgou-Bourgade S. for the GI Group of the FNCLCC and the FFCD: A phase III randomized trial of LV5FU2+CPT-11 vs LV5FU2 alone in adjuvant high risk colon cancer (FNCLCC Accord 02/FFCD 9802). J. Clin. Oncol. 23: (Suppl) abstract 3502, 2005.
-
-
-
-
14
-
-
38549110744
-
-
Van Cutsem E, Labianca R, Hossfeld D, Bodoky G, Roth A, Aranda E, Nordlinger B, Assadourian S, Wang K, Cunningham D (PETACC 3): Randomized phase III trial comparing infused irinotecan / 5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients. J. Clin. Oncol. 23: (Suppl) abstract 8, 2005.
-
Van Cutsem E, Labianca R, Hossfeld D, Bodoky G, Roth A, Aranda E, Nordlinger B, Assadourian S, Wang K, Cunningham D (PETACC 3): Randomized phase III trial comparing infused irinotecan / 5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients. J. Clin. Oncol. 23: (Suppl) abstract 8, 2005.
-
-
-
-
15
-
-
0035865363
-
Redefining the target: Chemotherapeutics asantiangiogenics
-
Miller K.D., Sweeney C.J., Sledge G.W. Jr.: Redefining the target: chemotherapeutics asantiangiogenics: J. Clin. Oncol. 19:1195-1206, 2001.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 1195-1206
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge Jr., G.W.3
-
16
-
-
2942615257
-
The antiangiogenic basis of metronomic chemotherapy
-
Kerbel R.S. and Kamen B.A.: The antiangiogenic basis of metronomic chemotherapy. Nat. Rev. Cancer 4:423-436, 2004.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
17
-
-
22844443499
-
Antibody against vascular endothelial growth factor (VEGF) inhibits angiogenic switch and liver metastasis in orthotopic xenograft model with site-dependent expression of VEGF
-
Takahashi Y., Mai M.: Antibody against vascular endothelial growth factor (VEGF) inhibits angiogenic switch and liver metastasis in orthotopic xenograft model with site-dependent expression of VEGF. J. Exp. Clin. Cancer Res. 24:237-243, 2005.
-
(2005)
J. Exp. Clin. Cancer Res
, vol.24
, pp. 237-243
-
-
Takahashi, Y.1
Mai, M.2
-
18
-
-
0032032201
-
Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line
-
Guichard S., Hennebelle I., Bugat R., Canal P.: Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line. Biochem. Pharmacol. 55:667-676, 1998.
-
(1998)
Biochem. Pharmacol
, vol.55
, pp. 667-676
-
-
Guichard, S.1
Hennebelle, I.2
Bugat, R.3
Canal, P.4
-
19
-
-
0033807408
-
Feasibility of a novel weekday-on/weekend-off oral UFT schedule aspostoperative adjuvant chemotherapy for colorectal cancer
-
Sadahiro S., Ohki S., Yamaguchi S., Takahashi T., Otani Y., Tsukikawa S., Yamamura T., Takemiya S., Nagasaki H., Nishiyama K., Fukushima T., Hiki Y., Yamaguchi S., Kumada K., Shimada H., Mitomi T., Makuuchi H.: Feasibility of a novel weekday-on/weekend-off oral UFT schedule aspostoperative adjuvant chemotherapy for colorectal cancer. Cancer Chemother. Pharmacol. 46:180-184, 2000.
-
(2000)
Cancer Chemother. Pharmacol
, vol.46
, pp. 180-184
-
-
Sadahiro, S.1
Ohki, S.2
Yamaguchi, S.3
Takahashi, T.4
Otani, Y.5
Tsukikawa, S.6
Yamamura, T.7
Takemiya, S.8
Nagasaki, H.9
Nishiyama, K.10
Fukushima, T.11
Hiki, Y.12
Yamaguchi, S.13
Kumada, K.14
Shimada, H.15
Mitomi, T.16
Makuuchi, H.17
-
20
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A., Figer A., Seymour M., Homerin M., Hmissi A., Cassidy J., Boni C., Cortes-Funes H., Cervantes A., Freyer G., Papamichael D., Le Bail N., Louvet C., Hendler D., de Braud F., Wilson C., Morvan F., Bonetti A.: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J. Clin. Oncol. 18:2938-2947, 2000.
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 2938-2947
-
-
de Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
Boni, C.7
Cortes-Funes, H.8
Cervantes, A.9
Freyer, G.10
Papamichael, D.11
Le Bail, N.12
Louvet, C.13
Hendler, D.14
de Braud, F.15
Wilson, C.16
Morvan, F.17
Bonetti, A.18
-
21
-
-
9144238357
-
X-ACT Study Group: Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial
-
Scheithauer W., McKendrick J., Begbie S., Borner M., Burns W.I., Burris H.A., Cassidy J., Jodrell D., Koralewski P., Levine E.L., Marschner N., Maroun J., Garcia-Alfonso P., Tujakowski J., Van Hazel G., Wong A., Zaluski J., Twelves C.; X-ACT Study Group: Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial. Ann. Oncol. 14:1735-1743, 2003.
-
(2003)
Ann. Oncol
, vol.14
, pp. 1735-1743
-
-
Scheithauer, W.1
McKendrick, J.2
Begbie, S.3
Borner, M.4
Burns, W.I.5
Burris, H.A.6
Cassidy, J.7
Jodrell, D.8
Koralewski, P.9
Levine, E.L.10
Marschner, N.11
Maroun, J.12
Garcia-Alfonso, P.13
Tujakowski, J.14
Van Hazel, G.15
Wong, A.16
Zaluski, J.17
Twelves, C.18
-
22
-
-
0025141337
-
What is the evidence that tumors are angiogencsis dependent?
-
Folkman J: What is the evidence that tumors are angiogencsis dependent? J. Natl. Cancer Inst. 84:4-6, 1990.
-
(1990)
J. Natl. Cancer Inst
, vol.84
, pp. 4-6
-
-
Folkman, J.1
-
23
-
-
0032795611
-
UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice
-
Yonekura K., Basaki Y., Chikahisa L., Okabe S., Hashimoto A., Miyadera K., Wierzba K., Yamada Y.: UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice. Clin. Cancer Res. 5:2185-2191, 1999.
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 2185-2191
-
-
Yonekura, K.1
Basaki, Y.2
Chikahisa, L.3
Okabe, S.4
Hashimoto, A.5
Miyadera, K.6
Wierzba, K.7
Yamada, Y.8
-
24
-
-
0035204403
-
Phase I trial of weekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer
-
Alonso V., Escudero P., Zorrilla M., Isla M.D., Herrero A., Mayordomo J.I., Martinez-Trufero J., Saenz A., Tres A., Anton A.: Phase I trial of weekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer. Eur. J. Cancer 37:2385-2391, 2001.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 2385-2391
-
-
Alonso, V.1
Escudero, P.2
Zorrilla, M.3
Isla, M.D.4
Herrero, A.5
Mayordomo, J.I.6
Martinez-Trufero, J.7
Saenz, A.8
Tres, A.9
Anton, A.10
-
25
-
-
18844403148
-
Weekly irinotecan plus UFT and leucovorin as first-line chemotherapy of patients with advanced colorectal cancer
-
Mendez M., Alfonso P.G., Pujol E., Gonzalez E., Castanon C., Cerezuela P., Lopez-Mateos Y., Cruz J.J.: Weekly irinotecan plus UFT and leucovorin as first-line chemotherapy of patients with advanced colorectal cancer. Invest. New. Drugs. 23:243-251, 2005.
-
(2005)
Invest. New. Drugs
, vol.23
, pp. 243-251
-
-
Mendez, M.1
Alfonso, P.G.2
Pujol, E.3
Gonzalez, E.4
Castanon, C.5
Cerezuela, P.6
Lopez-Mateos, Y.7
Cruz, J.J.8
-
26
-
-
21044457028
-
Weekly irinotecan (CPT-11) combined with uracil-tegafur (UFT) as first line treatment for metastatic colorectal carcinoma
-
Soc. Clin. Oncol, abstract 1344
-
Alonso V., Escudero P., Grandez R., Alvarez I., de Lobera R.A., Polo E., Corral M., Lara R., Puertolas T., Anton A.: Weekly irinotecan (CPT-11) combined with uracil-tegafur (UFT) as first line treatment for metastatic colorectal carcinoma. Proc. Am. Soc. Clin. Oncol. 22 abstract 1344, 2003.
-
(2003)
Proc. Am
, pp. 22
-
-
Alonso, V.1
Escudero, P.2
Grandez, R.3
Alvarez, I.4
de Lobera, R.A.5
Polo, E.6
Corral, M.7
Lara, R.8
Puertolas, T.9
Anton, A.10
-
27
-
-
33645454711
-
Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: Implications for circulating endothelial and progenitor cells as biomarkers forantiangiogenic therapy
-
Duda D.G., Cohen K.S., di Tomaso E., Au P., Klein R.J., Scadden D.T., Willett C.G., Jain R.K.: Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers forantiangiogenic therapy. J. Clin. Oncol. 24:1449-1453, 2006.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1449-1453
-
-
Duda, D.G.1
Cohen, K.S.2
di Tomaso, E.3
Au, P.4
Klein, R.J.5
Scadden, D.T.6
Willett, C.G.7
Jain, R.K.8
-
28
-
-
27644436870
-
Optimal biologic dose of metronomic chemotherapy regimens is associated with maximumantiangiogenic activity
-
Shaked Y., Emmenegger U., Man S., Cervi D., Bertolini F., Ben-David Y., Kerbel R.S.: Optimal biologic dose of metronomic chemotherapy regimens is associated with maximumantiangiogenic activity. Blood 106:3058-3061, 2005.
-
(2005)
Blood
, vol.106
, pp. 3058-3061
-
-
Shaked, Y.1
Emmenegger, U.2
Man, S.3
Cervi, D.4
Bertolini, F.5
Ben-David, Y.6
Kerbel, R.S.7
-
29
-
-
34547824591
-
Significance of Thymidine Phosphorylase in Metronomic Chemotherapy using CPT-11 and Doxifluridine for Advanced Colorectal Carcinoma
-
Ogata Y., Sasatomi T., Mori S., Matono K., Ishibashi N., Akagi Y., Fukushima T., Murakami H., Ushijima M., Shirouzu K.: Significance of Thymidine Phosphorylase in Metronomic Chemotherapy using CPT-11 and Doxifluridine for Advanced Colorectal Carcinoma. Anticancer Res. 27: 2605-2612, 2007.
-
(2007)
Anticancer Res
, vol.27
, pp. 2605-2612
-
-
Ogata, Y.1
Sasatomi, T.2
Mori, S.3
Matono, K.4
Ishibashi, N.5
Akagi, Y.6
Fukushima, T.7
Murakami, H.8
Ushijima, M.9
Shirouzu, K.10
-
30
-
-
38549144354
-
-
Japanese Society for Cancer of the Colon and Rectum: Multiinstitutional Registry of Large Bowel Cancer in Japan, Cases treated in 1995. (25), Tokyo, 2005.
-
Japanese Society for Cancer of the Colon and Rectum: Multiinstitutional Registry of Large Bowel Cancer in Japan, Cases treated in 1995. (Vol. 25), Tokyo, 2005.
-
-
-
-
31
-
-
28944432471
-
Characteristic differences between patients who have undergone surgical treatment for lung metastasis or hepatic metastasis from colorectal cancer
-
Iwasaki A., Shirakusa T., Yamashita Y., Noritomi T., Maekawa T., Hamada T.: Characteristic differences between patients who have undergone surgical treatment for lung metastasis or hepatic metastasis from colorectal cancer. Thorac. Cardiovasc. Surg. 53:358-364, 2005.
-
(2005)
Thorac. Cardiovasc. Surg
, vol.53
, pp. 358-364
-
-
Iwasaki, A.1
Shirakusa, T.2
Yamashita, Y.3
Noritomi, T.4
Maekawa, T.5
Hamada, T.6
|