Changes of hypoxia in primary lesion of nasopharyngeal carcinoma during the treatment course and the clinical value thereof

National Medical Journal of China

Volumn 87, Issue 38, 2007, Pages 2698-2762

  Zheng, Ying Jie ^a   Zhao, Chong ^a   Fab, Wei ^a   Liu, Hui ^a   Cui, Nian Ji ^a   Chen, Fu Jin ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

99Tcm HL91; Hypoxia; Nasopharyngeal neoplasm; Radionuclide imaging; Radiotherapy

Indexed keywords

UPENAZIME TC 99M;

ADULT; AGED; ARTICLE; CALCULATION; CANCER INHIBITION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; QUANTITATIVE ANALYSIS; RADIOACTIVITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR VOLUME;

ADULT; AGED; ANOXIA; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; TREATMENT OUTCOME;

EID: 38549127687     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hui EP, Chan AT, Pezzella F, et al. Coexpression of hypoxia-inducible factors 1 alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res, 2002, 8: 2595-2604.
2. Wakisaka N, wen QH, Yoshizaki T, et al. Association of vascular endothelial growth factor expression with angiogenesis and lymph node metastasis in nasopharyngeal carcinoma. Laryngoscope, 1999, 109: 810-414.
3. Nordsmark M, Overgaard J. A confirmation prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiotherapy and Oncology, 2000, 57: 39-43.
4. Brizel DM, Sibley GS, Prosnitz LR, et al. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys, 1997, 38: 285-289.
5. m-HL91, a putative hypoxic tracer, to detection of tumor hypoxia. J Nucl Med, 1999, 40: 854-861.
6. Tatsumi M, Yutani K, Kusuoka H, et al. Technetium-99m HL91 uptake as a tumour hypoxia marker: relationship to tumour blood flow. Eur J Nucl Med, 1999,26: 91-94.
7. m-BnAO (HL91): a non-nitroraromatic compound for hypoxic cell detection. Int J Radiat Oncol Biol Phys, 1998, 42: 737-740.
8. Chinese source.
9. Chinese source.
10. Murata R, Shibamoto Y, Sasai K, et al. Reoxygenation after single irradiation in rodent tumors of different types snd sizes. Int J Radiat Oncol Biol Phys, 1996, 34: 859-865.
11. Koh WJ, Rasey JS, Evans ML, et al. Imaging of hypoxia in human tumors with (F-18) fluoromisonidazole. Int J Radiat Oncol Biol Phys, 1992, 22:199-212.
12. Nordsmark M, Overgaard M, Overgaasd J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol, 1996, 41:31-39.
13. Eschmann SM, Paulsen F, Reimold M, et al. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med, 2005, 46: 253-260.
14. m-HL91 (4, 9-diaza-3, 3, 10, 10-tetramethyldodecan-2, 11-dione dioxime). Ann Nucl Med, 2003, 17: 131-138.
15. Dietz A, Rudat V, Conradt C, et al. Prognostic value of hemoglobin level for primary radiochemotherapy of head-neck carcinoma. HNO, 2000, 48: 655-664.
16. Chinese source.
17. Chinese source.