메뉴 건너뛰기




Volumn 5, Issue 2, 2007, Pages 693-697

Methylenetetrahydrofolate reductase C677T genotypes and clinical outcome following hematopoietic cell transplant

Author keywords

Graft versus host disease; Methotrexate; Polymorphism; Prophylaxis; Transplantation

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY;

EID: 38549089610     PISSN: 13040855     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (21)
  • 1
    • 0022624255 scopus 로고
    • Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia
    • Storb R, Deeg HJ, Whitehead J, et al. Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia. N Engl J Med. 1986;314(12):729-735.
    • (1986) N Engl J Med , vol.314 , Issue.12 , pp. 729-735
    • Storb, R.1    Deeg, H.J.2    Whitehead, J.3
  • 2
    • 0032528186 scopus 로고    scopus 로고
    • Immunosuppressive properties of methotrexate: Apoptosis and clonal deletion of activated peripheral T cells
    • Genestier L, Paillot R, Fournel S, Ferraro C, Miossec P, Revillard JP. Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. J Clin Invest. 1998; 102(2):322-328.
    • (1998) J Clin Invest , vol.102 , Issue.2 , pp. 322-328
    • Genestier, L.1    Paillot, R.2    Fournel, S.3    Ferraro, C.4    Miossec, P.5    Revillard, J.P.6
  • 3
    • 0016206826 scopus 로고
    • Effect of methotrexate on deoxyribonucleotide pools and DNA synthesis in human lymphocytic cells
    • Fridland A. Effect of methotrexate on deoxyribonucleotide pools and DNA synthesis in human lymphocytic cells. Cancer Res. 1974;34(8):1883-1888.
    • (1974) Cancer Res , vol.34 , Issue.8 , pp. 1883-1888
    • Fridland, A.1
  • 4
    • 0034724938 scopus 로고    scopus 로고
    • Effects of methotrexate on nucleotide pools in normal human T cells and the CEM T cell line
    • Budzik GP, Colletti LM, Faltynek CR. Effects of methotrexate on nucleotide pools in normal human T cells and the CEM T cell line. Life Sci. 2000;66(23):2297-2307.
    • (2000) Life Sci , vol.66 , Issue.23 , pp. 2297-2307
    • Budzik, G.P.1    Colletti, L.M.2    Faltynek, C.R.3
  • 5
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • Friso S, Choi SW, Girelli D, et al. A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A. 2002;99(8):5606-5611.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.8 , pp. 5606-5611
    • Friso, S.1    Choi, S.W.2    Girelli, D.3
  • 6
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetra-hydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetra-hydrofolate reductase. Nat Genet. 1995;10(1):111-113.
    • (1995) Nat Genet , vol.10 , Issue.1 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 7
    • 0023785897 scopus 로고
    • The effects of leucovorin (folinic acid) on methotrexate therapy in rheumatoid arthritis patients
    • Jul;
    • Tishler M, Caspi D, Fishel B, Yaron M. The effects of leucovorin (folinic acid) on methotrexate therapy in rheumatoid arthritis patients. Arthritis. Rheum. 1988 Jul;31(7):906-908.
    • (1988) Arthritis. Rheum , vol.31 , Issue.7 , pp. 906-908
    • Tishler, M.1    Caspi, D.2    Fishel, B.3    Yaron, M.4
  • 8
    • 0025887372 scopus 로고
    • Exacerbation of rheumatoid arthritis in patients treated with methotrexate after administration of folinic acid
    • Joyce DA, Will RK, Hoffman DM, Laing B, Blackbourn SJ. Exacerbation of rheumatoid arthritis in patients treated with methotrexate after administration of folinic acid. Ann Rheum Dis. 1991;50(12):913-914.
    • (1991) Ann Rheum Dis , vol.50 , Issue.12 , pp. 913-914
    • Joyce, D.A.1    Will, R.K.2    Hoffman, D.M.3    Laing, B.4    Blackbourn, S.J.5
  • 9
    • 0016860720 scopus 로고
    • Bone-marrow transplantation (second of two parts)
    • Thomas ED, Storb R, Clift RA, et al. Bone-marrow transplantation (second of two parts). N Engl J Med. 1975;292(17):895-902.
    • (1975) N Engl J Med , vol.292 , Issue.17 , pp. 895-902
    • Thomas, E.D.1    Storb, R.2    Clift, R.A.3
  • 10
    • 0016187133 scopus 로고
    • Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors
    • Glucksberg H, Storb R, Fefer A, et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors. Transplantation. 1974; 18(4):295-304.
    • (1974) Transplantation , vol.18 , Issue.4 , pp. 295-304
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3
  • 11
    • 0034606262 scopus 로고    scopus 로고
    • The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine
    • Kowa H, Yasui K, Takeshima T, Urakami K, Sakai F, Nakashima K. The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine. Am J Med Genet. 2000;96(6):762-764.
    • (2000) Am J Med Genet , vol.96 , Issue.6 , pp. 762-764
    • Kowa, H.1    Yasui, K.2    Takeshima, T.3    Urakami, K.4    Sakai, F.5    Nakashima, K.6
  • 12
    • 0035157121 scopus 로고    scopus 로고
    • The C677T mutation in the methylenetetrahydrofolate reductase gene: A genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients
    • van Ede AE, Laan RF, Blom HJ, et al. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients. Arthritis Rheum. 2001;44(11): 2525-2530.
    • (2001) Arthritis Rheum , vol.44 , Issue.11 , pp. 2525-2530
    • van Ede, A.E.1    Laan, R.F.2    Blom, H.J.3
  • 13
    • 0035725225 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in liver cirrhosis: Mechanisms and role in vascular and hepatic fibrosis
    • Garcia-Tevijano ER, Berasain C, Rodriguez JA, et al. Hyperhomocysteinemia in liver cirrhosis: mechanisms and role in vascular and hepatic fibrosis. Hypertension. 2001;38(5):1217-1221.
    • (2001) Hypertension , vol.38 , Issue.5 , pp. 1217-1221
    • Garcia-Tevijano, E.R.1    Berasain, C.2    Rodriguez, J.A.3
  • 14
    • 0036263469 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
    • Urano W, Taniguchi A, Yamanaka H, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics. 2002;12(3):183-190.
    • (2002) Pharmacogenetics , vol.12 , Issue.3 , pp. 183-190
    • Urano, W.1    Taniguchi, A.2    Yamanaka, H.3
  • 15
    • 32844475667 scopus 로고    scopus 로고
    • Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients
    • Winkelmayer WC, Kramar R, Sunder-Plassmann G, Födinger M. Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients. Kidney Int. 2005;68(6):2857-2862.
    • (2005) Kidney Int , vol.68 , Issue.6 , pp. 2857-2862
    • Winkelmayer, W.C.1    Kramar, R.2    Sunder-Plassmann, G.3    Födinger, M.4
  • 16
    • 0346102443 scopus 로고    scopus 로고
    • Kalayoglu-Besisik S, Caliskan Y, Sargin D, Gurses N, Ozbek U. Methylenetetrahydrofolate reductase C677T polymorphism and toxicity in allogeneic hematopoietic cell transplantation. Transplantation. 2003 27;76(12):1775-1777.
    • Kalayoglu-Besisik S, Caliskan Y, Sargin D, Gurses N, Ozbek U. Methylenetetrahydrofolate reductase C677T polymorphism and toxicity in allogeneic hematopoietic cell transplantation. Transplantation. 2003 27;76(12):1775-1777.
  • 17
    • 33846463385 scopus 로고    scopus 로고
    • Polymorphisms of the methylenetetrahydrofolate reductase gene and clinical outcomes in HLA-matched sibling allogeneic hematopoietic stem cell transplantation
    • Kim I, Lee KH, Kim JH, et al. Polymorphisms of the methylenetetrahydrofolate reductase gene and clinical outcomes in HLA-matched sibling allogeneic hematopoietic stem cell transplantation. Ann Hematol. 2007;86(1):41-48.
    • (2007) Ann Hematol , vol.86 , Issue.1 , pp. 41-48
    • Kim, I.1    Lee, K.H.2    Kim, J.H.3
  • 18
    • 33645708454 scopus 로고    scopus 로고
    • Donor methylenetetrahydrofolate reductase genotype is associated with graft-versus-host disease in hematopoietic stem cell transplant patients treated with methotrexate
    • Murphy N, Diviney M, Szer J, et al. Donor methylenetetrahydrofolate reductase genotype is associated with graft-versus-host disease in hematopoietic stem cell transplant patients treated with methotrexate. Bone Marrow Transplant. 2006;37(8):773-779.
    • (2006) Bone Marrow Transplant , vol.37 , Issue.8 , pp. 773-779
    • Murphy, N.1    Diviney, M.2    Szer, J.3
  • 19
    • 33747334957 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemia
    • Robien K, Bigler J, Yasui Y, et al. Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemia. Biol Blood Marrow Transplant. 2006;12(9):973-980.
    • (2006) Biol Blood Marrow Transplant , vol.12 , Issue.9 , pp. 973-980
    • Robien, K.1    Bigler, J.2    Yasui, Y.3
  • 20
    • 9344266353 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase genotype affects risk of relapse after hematopoietic cell transplantation for chronic myelogenous leukemia
    • Robien K, Ulrich CM, Bigler J, et al. Methylenetetrahydrofolate reductase genotype affects risk of relapse after hematopoietic cell transplantation for chronic myelogenous leukemia. Clin Cancer Res. 2004; 10(22):7592-7598.
    • (2004) Clin Cancer Res , vol.10 , Issue.22 , pp. 7592-7598
    • Robien, K.1    Ulrich, C.M.2    Bigler, J.3
  • 21
    • 4644337719 scopus 로고    scopus 로고
    • Impact of thrombophilic gene mutations and graft-versus-host disease on thromboembolic complications after allogeneic hematopoietic stem-cell transplantation
    • Pihusch M, Lohse P, Reitberger J, et al. Impact of thrombophilic gene mutations and graft-versus-host disease on thromboembolic complications after allogeneic hematopoietic stem-cell transplantation. Transplantation. 2004;78(6):911-918.
    • (2004) Transplantation , vol.78 , Issue.6 , pp. 911-918
    • Pihusch, M.1    Lohse, P.2    Reitberger, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.