A mitochondrial topoisomerase IA essential for late theta structure resolution in African trypanosomes

Molecular Microbiology

Volumn 67, Issue 4, 2008, Pages 820-829

  Scocca, Jane R ^a   Shapiro, Theresa A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; TOPOISOMERASE IA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; GENE SILENCING; IMMUNOLOCALIZATION; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE; TRYPANOSOMA BRUCEI;

ANIMALS; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; DNA, KINETOPLAST; MITOCHONDRIA; PHYLOGENY; RNA INTERFERENCE; TRYPANOSOMA BRUCEI BRUCEI;

PROTOZOA; TRYPANOSOMA BRUCEI;

EID: 38449123072     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2007.06087.x     Document Type: Article

References (37)

1. Abu-Elneel, K., Robinson, D.R., Drew, M.E., Englund, P.T. Shlomai, J. (2001) Intramitochondrial localization of universal minicircle sequence-binding protein, a trypanosomatid protein that binds kinetoplast minicircle replication origins. J Cell Biol 153 : 725 734.
2. Aravind, L., Leipe, D.D. Koonin, E.V. (1998) Toprim - a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins. Nucleic Acids Res 26 : 4205 4213.
3. Bakshi, R.P. Shapiro, T.A. (2004) RNA interference of Trypanosoma brucei topoisomerase IB: both subunits are essential. Mol Biochem Parasitol 136 : 249 255.
4. Bodley, A.L., Chakraborty, A.K., Xie, S., Burri, C. Shapiro, T.A. (2003) An unusual type IB topoisomerase from African trypanosomes. Proc Natl Acad Sci USA 100 : 7539 7544.
5. Borst, P., van der Ploeg, M., van Hoek, J.F., Tas, J. James, J. (1982) On the DNA content and ploidy of trypanosomes. Mol Biochem Parasitol 6 : 13 23.
6. Champoux, J.J. (2001) DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70 : 369 413.
7. Ciccarelli, F.D., Doerks, T., von Mering, C., Creevey, C.J., Snel, B. Bork, P. (2006) Toward automatic reconstruction of a highly resolved tree of life. Science 311 : 1283 1287.
8. Croft, S.L., Barrett, M.P. Urbina, J.A. (2005) Chemotherapy of trypanosomiases and leishmaniasis. Trends Parasitol 21 : 508 512.
9. Das, A., Dasgupta, A., Sengupta, T. Majumder, H.K. (2004) Topoisomerases of kinetoplastid parasites as potential chemotherapeutic targets. Trends Parasitol 20 : 381 387.
10. Drew, M.E. Englund, P.T. (2001) Intramitochondrial location and dynamics of Crithidia fasciculata kinetoplast minicircle replication intermediates. J Cell Biol 153 : 735 744.
11. Duguet, M. (1997) When helicase and topoisomerase meet! J Cell Sci 110 : 1345 1350.
12. Duguet, M., Serre, M.C. Bouthier de La Tour, C. (2006) A universal type IA topoisomerase fold. J Mol Biol 359 : 805 812.
13. El-Sayed, N.M., Myler, P.J., Blandin, G., Berriman, M., Crabtree, J., Aggarwal, G., et al. (2005) Comparative genomics of trypanosomatid parasitic protozoa. Science 309 : 404 409.
14. Goodwin, A., Wang, S.W., Toda, T., Norbury, C. Hickson, I.D. (1999) Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe. Nucleic Acids Res 27 : 4050 4058.
15. Hiasa, H. Marians, K.J. (1994) Topoisomerase III, but not topoisomerase I, can support nascent chain elongation during theta-type DNA replication. J Biol Chem 269 : 32655 32659.
16. Hiasa, H. Marians, K.J. (1996) Two distinct modes of strand unlinking during theta-type DNA replication. J Biol Chem 271 : 21529 21535.
17. Kulikowicz, T. Shapiro, T.A. (2006) Distinct genes encode type II topoisomerases for the nucleus and mitochondrion in the protozoan parasite Trypanosoma brucei. J Biol Chem 281 : 3048 3056.
18. Li, Z., Mondragon, A., Hiasa, H., Marians, K.J. DiGate, R.J. (2000) Identification of a unique domain essential for Escherichia coli DNA topoisomerase III-catalysed decatenation of replication intermediates. Mol Microbiol 35 : 888 895.
19. Liu, B., Liu, Y., Motyka, S.A., Agbo, E.E. Englund, P.T. (2005) Fellowship of the rings: the replication of kinetoplast DNA. Trends Parasitol 21 : 363 369.
20. Liu, B., Molina, H., Kalume, D., Pandey, A., Griffith, J.D. Englund, P.T. (2006) Role of p38 in replication of Trypanosoma brucei kinetoplast DNA. Mol Cell Biol 26 : 5382 5393.
21. Liu, L.F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu Rev Biochem 58 : 351 375.
22. Lukes, J., Guilbride, D.L., Votypka, J., Zikova, A., Benne, R. Englund, P.T. (2002) Kinetoplast DNA network: evolution of an improbable structure. Eukaryot Cell 1 : 495 502.
23. Maniatis, T., Fritsch, E.F. Sambrook, J. (1982) Molecular cloning A laboratory manual. Cold Spring Harbor, NY : Cold Spring Harbor Laboratory.
24. Oberholzer, M., Morand, S., Kunz, S. Seebeck, T. (2006) A vector series for rapid PCR-mediated C-terminal in situ tagging of Trypanosoma brucei genes. Mol Biochem Parasitol 145 : 117 120.
25. Ryan, K.A. Englund, P.T. (1989) Synthesis and processing of kinetoplast DNA minicircles in Trypanosoma equiperdum. Mol Cell Biol 9 : 3212 3217.
26. Ryan, K.A., Shapiro, T., Rauch, C.A., Griffith, J.D. Englund, P.T. (1988) A knotted free minicircle in kinetoplast DNA. Proc Natl Acad Sci USA 85 : 5844 5848.
27. Shapiro, T.A. (1994) Mitochondrial topoisomerase II activity is essential for kinetoplast DNA minicircle segregation. Mol Cell Biol 14 : 3660 3667.
28. Shapiro, T.A. Englund, P.T. (1995) The structure and replication of kinetoplast DNA. Annu Rev Microbiol 49 : 117 143.
29. Shlomai, J. (2004) The structure and replication of kinetoplast DNA. Curr Mol Med 4 : 623 647.
30. Tse-Dinh, Y.C. (1998) Bacterial and archeal type I topoisomerases. Biochim Biophys Acta 1400 : 19 27.
31. Ullu, E., Tschudi, C. Chakraborty, T. (2004) RNA interference in protozoan parasites. Cell Microbiol 6 : 509 519.
32. Wang, J.C. (1996) DNA topoisomerases. Annu Rev Biochem 65 : 635 692.
33. Wang, J.C. (2002) Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol 3 : 430 440.
34. Wang, Y., Lyu, Y.L. Wang, J.C. (2002) Dual localization of human DNA topoisomerase III alpha to mitochondria and nucleus. Proc Natl Acad Sci USA 99 : 12114 12119.
35. Wang, Z. Englund, P.T. (2001) RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA. EMBO J 20 : 4674 4683.
36. Wu, L. Hickson, I.D. (2003) The bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426 : 870 874.
37. Zhu, Q., Pongpech, P. DiGate, R.J. (2001) Type I topoisomerase activity is required for proper chromosomal segregation in Escherichia coli. Proc Natl Acad Sci USA 98 : 9766 9771.