Role of regulator of G-protein signaling 2 (RGS2) in periodontal ligament cells under mechanical stress

Cell Biochemistry and Function

Volumn 25, Issue 6, 2007, Pages 753-758

  Santos De Araujo, Rui M ^a   Oba, Yasuo ^a   Moriyama, Keiji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

cAMP; Mechanical stress; Periodontal ligament; RGS2

Indexed keywords

2',5' DIDEOXYADENOSINE; CYCLIC AMP; OLIGONUCLEOTIDE; RGS2 PROTEIN; 2',3' DIDEOXYADENOSINE; 2',5'-DIDEOXYADENOSINE; ANTISENSE OLIGONUCLEOTIDE; DRUG DERIVATIVE; RGS PROTEIN; RGS2 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN CELL; MECHANICAL STRESS; NORMAL HUMAN; PERIODONTAL LIGAMENT; PREMOLAR TOOTH; PRIORITY JOURNAL; PROTEIN EXPRESSION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

BLOTTING, WESTERN; CELLS, CULTURED; CYCLIC AMP; DIDEOXYADENOSINE; GENE EXPRESSION REGULATION; HUMANS; OLIGONUCLEOTIDES, ANTISENSE; PERIODONTAL LIGAMENT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RGS PROTEINS; STRESS, MECHANICAL; TIME FACTORS;

EID: 38449119009     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1400     Document Type: Article

References (32)

1. Downes GB, Gautam N. The G protein subunit gene families. Genomics 1999; 62: 544-552.
2. Ishii M, Kurachi Y. Physiological actions of regulators of G-protein signaling (RGS) proteins. Life Sci 2003; 74: 163-171.
3. Song L, Zmijewski JW, Jope RS. RG S2: regulation of expression and nuclear localization. Biochem Biophys Res Commun 2001; 208: 102-106.
4. Backhus LE, DeRisi J, Bisson LF. Functional genomic analysis of a commercial wine strain of Saccharomyces cerevisiae under differing nitrogen conditions. FEMS Yeast Res 2001; 1: 111-125.
5. Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS. Second messengers regulate RGS2 expression which is targeted to the nucleus. Biochim Biophys Acta 2001; 1541: 201-211.
6. Beadling C, Druey KM, Richter G, Kehrl JH, Smith KA. Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes. J Immunol 1999; 162: 2677-2682.
7. Pepperl DJ, Shah-Basu S, VanLeeuwen D, Granneman JG, MacKenzie RG. Regulation of RGS mRNAs by cAMP in PC12 cells. Biochem Biophys Res Commun 1998; 243: 52-55.
8. Versele M, de Winde JH, Thevelein JM. A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2. EMBO J 1998; 18: 5577-5591.
9. Tseng CC, Zhang XY. Role of regulator of G protein signaling in desensitization of the glucose-dependent insulinotropic peptide receptor. Endocrinology 1998; 139: 4470-4475.
10. Sinnarajah S, Dessauer CW, Srikumar D, et al. RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III. Nature 2001; 40: 1051-1055.
11. Salim S, Sinnarajah S, Kehrl JH, Dessauer CW. Identification of RGS2 and type Vadenylyl cyclase interaction sites. J Biol Chem 2003; 278: 5842-5849.
12. Mitchell DL, West JD. Attempted orthodontic movement in the presence of suspected ankylosis. Am J Orthod 1975; 68: 404-411.
13. Araujo RMS, Oba Y, Moriyama K. Identification of genes related to mechanical stress in human periodontal ligament cells using microarray analysis. J Periodontal Res 2007; 42: 15-22.
14. Han X, Amar S. Identification of genes differentially expressed in cultured human periodontal ligament fibroblasts vs. human gingival fibroblasts by DNA microarray analysis. J Dent Res 2002; 81: 399-405.
15. Kagami S, Urushihara M, Kondo S, et al. Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells. Exp Cell Res 2001; 268: 274-283.
16. Alhashimi N, Frithiof L, Brudvik P, Bakhiet M. Orthodontic tooth movement and de novo synthesis of proinflammatory cytokines. Am J Orthod Dentofacial Orthop 2001; 119: 307-312.
17. Lowney JJ, Norton LA, Shafer DM, Rossomando EF. Orthodontic forces increase tumor necrosis factor alpha in the human gingival sulcus. Am J Orthod Dentofacial Orthop 1995; 108: 519-524.
18. Shimizu N, Ozawa Y, Yamaguchi M, Goseki T, Ohzeki K, Abiko Y. Induction of COX-2 expression by mechanical tension force in human periodontal ligament cells. J Periodontol 1998; 69: 670-677.
19. Ohzeki K, Yamaguchi Shimizu N, Abiko Y. Effect of cellular aging on the induction of cyclooxygenase-2 by mechanical stress in human periodontal ligament cells. Mech Ageing Dev 1999; 108: 151-163.
20. Kanzaki H, Chiba M, Shimizu Y, Mitani H. Periodontal ligament cells under mechanical stress induce osteoclastogenesis by receptor activator of nuclear factor kappaB ligand up-regulation via prostaglandin E2 synthesis. J Bone Miner Res 2002; 17: 210-220.
21. Nakagawa M, Kukita T, Nakasima A, Kurisu K. Expression of the type I collagen gene in rat periodontal ligament during tooth movement as revealed by in situ hybridization. Arch Oral Biol 1994; 39: 289-294.
22. Matsuda N, Yokoyama K, Takeshita S, Watanabe M. Role of epidermal growth factor and its receptor in mechanical stress-induced differentiation of human periodontal ligament cells in vitro. Arch Oral Biol 1998; 43: 987-997.
23. Yousefian J, Firouzian F, Shanfeld J, Ngan P, Lanese R, Davidovitch Z. A new experimental model for studying the response of periodontal ligament cells to hydrostatic pressure. Am J Orthod Dentofacial Orthop 1995; 108: 402-409.
24. Somjen D, Binderman I, Berger E, Harell A. Bone remodelling induced by physical stress is prostaglandin E2 mediated. Biochim Biophys Acta 1980; 627: 91-100.
25. Davidovitch Z, Shanfeld JL. Cyclic AMP levels in alveolar bone of orthodontically-treated cats. Arch Oral Biol 1975; 20: 567-574.
26. Davidovitch Z, Montgomery PC, Gustafson GT, Eckerdal O. Cellular localization of cyclic AMP in periodontal tissues during experimental tooth movement in cats. Calcif Tissue Res 1976; 31: 317-329.
27. Davidovitch Z, Montgomery PC, Yost RW, Shanfeld JL. Immuno-histochemical localization of cyclic nucleotides in mineralized tissues: mechanically-stressed osteoblasts in vivo. Anat Rec 1978; 192: 363-373.
28. Miles RR, Sluka JP, Santerre RF, et al. Dynamic regulation of RGS2 in bone: potential new insights into parathyroid hormone signaling mechanisms. Endocrinology 2000; 141: 28-36.
29. Roy AA, Lemberg KE, Chidiac P. Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions. Mol Pharmacol 2003; 64: 587-593.
30. Heximer SP, Watson N, Linder ME, Blumer KJ, Hepler JR. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proc Natl Acad Sci USA 1997; 94: 14389-14393.
31. Heximer SP, Srinivasa SP, Bernstein LP, et al. G protein selectivity is a determinant of RGS2 function. J Biol Chem 1999; 274: 34253-34259.
32. Li Y, Hashim S, Anand-Srivastava MB. Angiotensin 11-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells. Cardiovasc Res 2005; 66: 503-511.