The altered autonomic nervous system activity in iron deficiency anemia

Tohoku Journal of Experimental Medicine

Volumn 212, Issue 4, 2007, Pages 397-402

  Yokusoglu, Mehmet ^a   Nevruz, Oral ^a   Baysan, Oben ^a   Uzun, Mehmet ^a   Demirkol, Sait ^a   Avcu, Ferit ^a   Koz, Cem ^a   Çetin, Turker ^a   Hasimi, Adnan ^a   Ural, Ali Ugur ^a   Isik, Ersoy ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Anemia; Autonomic functions; Heart rate variability; Iron deficiency

Indexed keywords

C REACTIVE PROTEIN; CALCIUM; CYANOCOBALAMIN; FOLIC ACID; IRON; POTASSIUM CHANNEL;

ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD RHEOLOGY; BLOOD VISCOSITY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CAROTID BODY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLIC ACID BLOOD LEVEL; HEART DISEASE; HEART RATE VARIABILITY; HOLTER MONITORING; HUMAN; HYPOXIA; IRON BINDING CAPACITY; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; MALE; MITOCHONDRIAL RESPIRATION; POTASSIUM CHANNELOPATHY; PROTEIN BLOOD LEVEL; SYMPATHETIC TONE; VITAMIN BLOOD LEVEL; ADRENERGIC SYSTEM; ELECTROCARDIOGRAPHY; HEART RATE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; ANEMIA, IRON-DEFICIENCY; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; HEART RATE; HUMANS; MALE; SYMPATHETIC NERVOUS SYSTEM;

EID: 38449118677     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.212.397     Document Type: Article

References (36)

1. Akyol, A., Alper, A.T., Cakmak, N., Hasdemir, H., Eksik, A., Oguz, E., Erdinler, I., Ulufer, F.T. & Gurkan, K. (2006) Long-term effects of cardiac resynchronization therapy on heart rate and heart rate variability. Tohoku J. Exp. Med., 209, 337-346.
2. Asahara, K., Ando, Y, Tanaka, Y., Yi, S., Yamashita, T. & Ando M. (1993) Secondary hypoplastic anemia in patients with familial amyloidotic polyneuropathy. Acta Haematol., 90, 130-135.
3. Broberg, C.S., Bax, B.E., Okonko, D.O., Rampling, M.W., Bayne, S., Harries, C., Davidson, S.J., Uebing, A., Khan, A.A., Thein, S., Gibbs, J.S., Burman, J. & Gatzoulis, M.A. (2006) Blood viscosity and its relationship to iron deficiency, symptoms, and exercise capacity in adults with cyanotic congenital heart disease. J. Am. Coll. Cardiol., 48, 356-365.
4. Casolo, G.C., Stroder, P., Signorini, C., Calzolari, F., Zucchini, M., Balli, E., Sulla, A. & Lazzerini, S. (1992) Heart rate variability during the acute phase of myocardial infarction Circulation, 85, 2073-2079.
5. Connes, P., Martin, C., Barthelemy, J.C., Monchanin, G., Atchou, G., Forsuh, A., Massarelli, R., Wouassi, D., Thiriet, P. & Pichot, V. (2006) Nocturnal autonomic nervous system activity impairment in sickle cell trait carriers. Clin Physiol Funct Imaging, 126, 87-91
6. Dundaroz, M.R., Denli, M., Uzun, M., Aydin, H.I., Sarici, S.U., Yokusoglu, M. & Ulgen, S. (2001) Analysis of heart rate variability in children with primary nocturnal enuresis. Int. Urol. Nephrol., 32, 393-397.
7. Franzoni, F., Galetta, F., Di Muro, C., Buti, G., Pentimone, F. & Santoro, G. (2004) Heart rate variability and ventricular late potentials in beta-thalassemia major. Haematologica, 89, 233-234.
8. Freeman, R., Saul, J.P., Roberts, M.S., Berger, R.D., Broadbridge, C. & Cohen, R.J. (1991) Spectral analysis of heart rate in diabetic autonomic neuropathy. A comparison with standard tests of autonomic function. Arch. Neurol., 48, 185-190.
9. Gehi, A., Ix, J., Shlipak, M., Pipkin, S.S. & Whooley, M.A. (2005) Relation of anemia to low heart rate variability in patients with coronary heart disease (from the Heart and Soul study). Am. J. Cardiol., 95, 1474-1477.
10. Hattori, A., Hayano, J., Fujimoto, S., Ando, N., Mizuno, K., Kamei, M., Kobayashi, S., Ishikawa, T. & Togari, H. (2007) Cardiac vagal activation by adrenocorticotropic hormone treatment in infants with West syndrome. Tohoku J. Exp. Med., 211, 133-139.
11. Kitney, R.I., Byrne, S., Edmonds, M.E., Watkins, P.J. & Roberts, V.C. (1982) Heart rate variability in the assessment of autonomic diabetic neuropathy. Automedica., 4, 155-167.
12. Lahiri, S., Roy, A., Baby, S.M., Hoshi, T., Semtnza, G.L. & Prabhakar, N.R. (2006) Oxygen sensing in the body. Prog. Biophys. Mol. Biol., 91, 249-286.
13. Lakhotia, M., Shah, P.K., Gupta, A., Jain, S.S., Agarwal, M. & Dadhich, S. (1996) Clinical assessment of autonomic functions in anemics. J. Assoc. Physicians India, 44, 534-536.
14. Malik, M., Farrell, T., Cripps, T. & Camm, A.J. (1989) Heart rate variability in relation to prognosis after myocardial infarction: selection of optimal processing techniques. Eur. Heart J., 10, 4060-1074.
15. Malpas, S.C. & Purdie, G.L. (1990) Circadian variation of heart rate vasiability. Cardiovasc. Res., 24, 210-213.
16. Muller, R., Steffen, H.M., Brunner, R., Saric, J., Pollok, M., Baldamus, C.A. & Kaufmann, W. (1991) Changes in the alpha adrenergic system and thcrease in blood pressure with recombinant human erythropoietin (rHuEpo) therapy for renal anemia. Clin. Invest. Med., 14, 614-622.
17. Nevruz, O., Yokusoglu, M., Uzun, M., Demirkol, S., Avcu, F., Baysan, O. Koz, C., Cetin, T., Sag, C., Ural, A.U. & Isik, E. (2007) Cardiac autonomic functions are altered in patients with acute leukemia, assessed by heart rate variability. Tohoku J. Exp. Med., 211, 121-126.
18. O'Brien, I.A., O'Hare, P. & Corrall, R.J. (1986) Heart rate variability in healthy subjects: effect of age and the derivation of normal ranges for tests of autonomic function. Br. Heart J., 55, 348-354.
19. Odemuyiwa, O., Malik, M., Farrell, T., Bashir, Y., Poloniecki, J., & Camm, J. (1991) Comparison of predictive characteristics of heart rate variability index and left ventricular ejection fraction for all-cause mortality, arrhythmic events and sudden death after acute myocardial infarction. Am. J. Cardiol., 68, 434-439.
20. Oka, T., Matsukura, M., Okamoto, M., Harada, N., Kitano, T., Miike, T. & Futatsuka, M. (2002) Autoromic nervous functions in fetal type Minamata disease patients: assessment of heart rate variability. Tohoku J. Exp. Med., 198, 215-221.
21. Ponikowski, P., Anker, S.D., Chua, T.P., Szelemej, R., Piepoli, M., Adamopoulos, S., Webb-Peploe, K., Harrington, D., Banasiak, W., Wrabec, K. & Coats, A.J. (1997) Depressed heart rate variability as an independent predictor of death in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am. J. Cardiol., 79, 1645-1650.
22. Reinhart, W.H. (1992) The influence of iron deficiency on erythrocyte deformability. Br. J. Haematol., 80, 550-555.
23. Romero Mestre, J.C., Hernandez, A., Agramonte, O. & Hernandez, P. (1997) Cardiovascular autonomic dysfunction in sickle cell anemia: a possible risk factor for sudden death? Clin. Autom. Res., 7, 121-125.
24. Sampei, M., Murata, K., Dakeishi, M. & Wood, D.C. (2006) Cardiac autonomic hypofunction in preschool children with short nocturnal sleep. Tohoku J. Exp. Med., 208, 235-242.
25. Sands, K.E., Appel, M.L., Lilly, L.S., Schoen, F.J., Mudge, G.H., Jr. & Cohen, R.J. (1989) Power spectrum analysis of heart rate variability in human cardiac transplant recipients. Circulation, 79, 76-82.
26. Saul, J.P., Arai, Y., Berger, R.D., Lilly, L.S., Colucci, W.S. & Cohen, R.J. (1988) Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis. Am. J. Cardiol., 61, 1292-1299.
27. Schultz, H.D. & Sun, S.Y. (2000) Chemoreflex function in heart failure. Heart Fail Rev., 5, 45-56.
28. Sozen, A.B., Demirel, S., Akkaya, V., Kudat, H., Tukek, T., Yeneral, M., Ozcan, M., Guven, O. & Korkut, F. (1998) Autonomic dysfunction in vitamin B12 deficiency: a heart rate variability study. J. Auton Nerv. Syst., 71, 25-27.
29. Task Force of the European Society of Cardiology the North American Society of Pacing Electrophysiology (1996) Heart Rate Variability. Standards of Measurement, Physiological Interpretation, and Clinical Use. Circulation, 93, 1043-1065.
30. Tillmann, W. & Schroter, W. (1980) Deformability of erythrocytes in iron deficiency anemia. Blut, 40, 179-186.
31. Unalacak, M., Aydin, M., Ermis, B., Ozeren, A., Sogut, A., Demirel, F. & Unluoglu, I. (2004) Assessment of cardiac autonomic regulation in children with monosymptomatic nocturnal enuresis by analysis of heart rate variability. Tohoku J. Exp. Med., 204, 63-69.
32. Vaishnav, S., Stevenson, R., Marchant, B., Lagi, K., Ranjadayalan, K. & Timmis, A.D. (1994) Relation between heart rate variability early after acute myodardial infarction and long-term mortality. Am. J. Cardiol., 73, 653-657.
33. Vaya, A., Simo, M., Santaolaria, M., Todoli, J. & Aznar, J. (2005) Red blood cell deformability in iron deficiency anaemia. Clin. Hemorheol. Microcirc., 33, 75-80.
34. Veglio, F., Melchio, R., Rabbia, F., Molino, P., Genova, G.C., Martini, G., Schiavone, D., Piga, A. & Chiandussi, L. (1998) Blood pressure and heart rate in young thalassemia major patients. Am. J. Hypertens., 11, 539-547.
35. Yokusoglu, M., Ozturk, S., Uzun, M., Baysan, O., Demirkol, S., Caliskaner, Z., Dundaroz, R., Sag, C., Karaayvaz, M. & Isik, E. (2007) Heart rate variability in patients with allergic rhinitis. Mil. Med., 172, 98-101.
36. Zhu, H., Jackson, T. & Bunn, H.F. (2002) Detecting and responding to hypoxia. Nephrol. Dial Transplant., 17, Suppl. 1, 3-7.